need help with your account or subscription? click here to email us (or see the contact page)
join telegramNEW! discord
jump to exam page:
search for anything ⋅ score predictor (“predict me!”)

You must be logged in to vote!
Retired NBME 22 Answers

nbme22/Block 4/Question#47 (reveal difficulty score)
A 56-year-old woman comes to the physician ...
Maintenance of basement membrane integrity 🔍 / 📺 / 🌳 / 📖
tags:

 Login (or register) to see more


 +14  upvote downvote
submitted by bubbles(79)
The site was recently locked🔒
It can be re-accessed by making a purchase.

Purchase your membership here
unscramble the site ⋅ become a member$279$49

atmBsnee ebammner ternytiig si teh teertdanmin of flul nugl rcyveero olwfgnoil ayunolrmp lsun.it

amuy:mrS

()1 ssol of sanbteme eenbrmma ntygritei is latiiccr ni tnnrdgmeiie het tpoin“ of no t,”reunr nad irobntetusc ot eht aynltbiii ot baeerlhtsis lnrmao lung arcirehettuc tihw pnmortoio of ois;frsbi

2)( sols of lhaeieltpi cll,se heetaonldli sllc,e dan ambesnet neembarm iytingrte in ulsua tiineitsatrl mnponeiau dsstoeiaac twhi ahociitdip maorunlpy frissibo saeld ot esdtoyrde gnul hctearciteur dna eeptulapr isiorfs;b

3)( rsomgaitnrfn wothrg af-cβrot si eseca,snyr utb ton enirtely ifsnt,cufei ot poortem mnteperan of;bisirs

4)( eepstirtns niiyinntta/urjragtern/i is iiacltrc rfo teh pinproogtaa fo bsfiri;os

)(5 iihcpdaiot mynualrop ifibssro is an eaplexm fo a sscreop rltdeea ot het erneseipcst fo na eg“t(nas”)in, icchorn ofia,lnamnmit nad issbfo;ir dna

(6) uniueq clles aer tlicirac aclellur ypesrla ni hte nglourieta fo irsfisb.o

acitnt:io nt..P//isC2s4M1hmwpi/r.agn6cl:l/.pwtwnc42o/mte5ih/bvc

unscramble the site ⋅ become a member$279$49
kernicterusthefrog  volyeL +
endochondral1  yan FA or taomaph ro wludor cranot?relio +
endochondral1  ro saw hits a nado?rm +
taediggity  Teyp II cespuotneym esver sa hte stem clle csrrpr,ouse out/w heots u'eory omer or sels fd:ekuc FA 0022 gp 166 +4

Quoting Dr Sattar, if an injury or cut is too deep so as the regenerative/stem cells are removed/damaged - then healing can only occur by repair. Thus, in this case, the stem cells of the lung aka Type 2 pneumocytes reside in the basement membrane - so, injury to basement membrane would damage type 2 pneumocytes and would NOT allow restoration of normal lung architecture. That's why maintenance of basement membrane integrity is the most important determining factor to distinguish whether tissue will heal by regeneration (restore normal architecture) or repair (fibrosis/scarring). Same concept can be applied to skin (basal cells) and intestines (crypt cells).


You must be logged in to vote!

 +11  upvote downvote
submitted by drdoom(1206)
The site was recently locked🔒
It can be re-accessed by making a purchase.

Purchase your membership here
unscramble the site ⋅ become a member$279$49

You avhe to nhtik tboau ti isht ya:w eht mabnstee mbneream is het gfoafn”lscd“i on ihhcw srtee]trivo[a inglhae usrc.oc So, ey,s mets cslle teyp( II ynpceoset)um odluw be eivoldvn ni ttah ahileng orpssce tbu heyt oundl’tc eetsror hte rnoalm hitrrectucea o“n( ”mnra)atseoilbi wotihtu the eontelks’‘ of hte tsabemne amnemerb lgnliet ehmt hewre to ,og ni ahtw rodinitec ot ro,gw hcwih awy si “u”,p tce. fI eth sabmetne mbeanmer si deot,seydr ouy acn sllti get ein,lhga but it wtn’o eb airnodegz ihaegnl -- ’illt eb dzeisgdaroni il,hegna hwhci deos nto pepraa as lmanro s.tesiu dgoDienris(az neighal is trtbee nath on hignea,l tbu thutiwo a MB, eht eigrtneeagrn ecsll nt’do hvea yna o”rdeni“cit adn fhreeerto actn’ rosrete the mlorna etiureh.cat)rc

unscramble the site ⋅ become a member$279$49
drdoom  by virttor"seae" i mean englaih wihhc rosesert the osireupv n(da lm)anor stsiue ecautrthie.cr rfo tath ot hn,apep ouy ened na icattn snambeet eem!nrmab +2
nwinkelmann  ,Yse sthi a trgae uymarms ot het sotp by bub@slbe nad hte atirecl eh eptso!d Ahroent awy to ikhnt of teh oqnisteu is ,ton htaw suaecs e,rpiar tbu htaw csuase beierrilvser iysrujorbs.ni/if ahTt craitle iledexpan an etrmpeixne ahtt sohwde GTa-etbF asw yescarsen ot tiaiinte ,isrofisb ubt fi BM swa anttci dan eF-TGbat swa mdveore, eth srobfisi itdn'd rsestpi, i.e. tcntai BM si ceevopittr iaatnsg Ta-Get.Fb :s41ww/tnin4s/n5gevma/.c.hlp2o6/r.2Ppclt./hitwC/cmiMb +1


You must be logged in to vote!

 +1  upvote downvote
submitted by shaydawn88(8)
The site was recently locked🔒
It can be re-accessed by making a purchase.

Purchase your membership here
unscramble the site ⋅ become a member$279$49

I odluw ithnk nouloistre enolvsvi eth mtse celsl e(pyt II psceyunm)ote. Is teh ttncai tabeesmn nmeearmb eth swearn bseeuca ti isltmi ?redpas

unscramble the site ⋅ become a member$279$49
aesalmon  I wolud losa ielk ot knwo if enynoa anc rseanw sthi sinqtoeu - I saw it sa a aStrta n"oe ,yda oen ek,we noe onmht" kidn of eoqun.ist Ist pbolryba yrev iepslm ubt I litls tn'do teg it +
bubbles  I tesopd a wen emcmtno ieni:nlapgx temsbnea enmmrbea iytirengt is het entssortg ndnetetrima fo lulf xf reycreov wgloofiln umypnlora tuinls ): +5
drdoom  Yuo veah ot tihkn ubtoa ti hits awy: eth saebnetm emaembnr si hte do”fl“scngaif on chhwi v[aoesrt]reti ahilegn cc.usor ,So yes, stem ellcs etyp( II tsece)uynpom wudol eb ldovienv ni thta lahneig scoreps ubt htye ut’londc soerert hte mal*orn* tthrccauiere n“(o nomaib”i)retlas tuhwiot het se’ltkone‘ of eht eebstnma bmaemrne litngle mhte ehrew ot og, ni thwa eotiincrd to wo,rg hchiw ywa is ”p“,u et.c fI eth mtaseneb emeranbm is et,dysdoer uoy nca itsll egt ,ahgenil tub ti t’won be dozriegna anheilg -- tl’il eb odadge**riszni ,aeginlh hhwic sdoe otn rpapea as monalr us.iest is(odaizenDrg ahinelg is retteb nath no hgeinl,a utb wouihtt a ,BM eht aernetenggir clsle ’ondt ehva nay “ritcieo”nd adn thfeerero c’nta treosre hte oalrmn rct)tiarceh.eu +9
nwinkelmann  ,Yes tsih a agrte muarsmy to teh tpos by sub@bleb adn teh rcileat he !eotpds treAnho ywa to khtni fo eht otnusiqe si tno, htwa scause erapir, ubt wath euscas eirsbleerrvi rysioijifn/s.bur htaT ritelca adplineex an meerpxient thta hedwso eTFb-aGt asw yserecnas to nieittia ifsisro,b but fi BM was atcint nad etbFGa-T wsa mveerd,o eth ssobrifi dtdin' tri,pess e.i. tctian MB si teotecpivr natiasg FGTea-t.b n//ptn.:4ni2/itmhc21tCvmei.awM6co.ps.hwl4bgw5s//rlP/c +


You must be logged in to vote!

 +1  upvote downvote
submitted by ls3076(92)
The site was recently locked🔒
It can be re-accessed by making a purchase.

Purchase your membership here
unscramble the site ⋅ become a member$279$49

can aynoen axnelip ywh ()D ampetliasa is tcrercnio?

unscramble the site ⋅ become a member$279$49
angelaq11  beuseac palseiaamt udwol be a mnnitftrsaoaor of eth aorlmn ucttareirhce of teh stperiyraro pleeiimuht ot eon htat sedo nto noglbe tehr,e in seserpno to ornchic airritno.it isTh mnwoa adh umpaclccoeon enpmounai tath asw eccrlyrot an(d I aerd asy opt)plrym era,dtte so esh drefufes na tauce tharre hatn a noicchr stluni. +
blueberrymuffinbabey  ubcaese lpieamasat in'st woh eth laornm innliaogreeghtnera/e rpsesnoe henapps ni hte e.villoa eth ypet 2 cumpoeetyns ersve as semt rr/rspelelccsuso ot hbot pyet 1 dan 2 mpeeyostcun os het tgiaerereonn si not mli.aetsapa +1


You must be logged in to vote!

Must-See Comments from nbme22

sacredazn on Unrearranged immunoglobulin gene
seagull on Decreased binding of RNA polymerase
seagull on Anticholinergic
mcl on Area labeled ‘D’
liverdietrying on Release of stored thyroid hormone from a ...
kernicterusthefrog on Displacement
keycompany on Negative nitrogen balance
joha961 on Displacement
imgdoc on Area labeled ‘C’ (Abducens nucleus, right)
alwaysanonymous on 25 mL/cm H2O
drdoom on 1 in 600
seagull on Glutamine
yotsubato on Phase variation
bubbles on Acute retroviral infection

search for anything NEW!