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Welcome to blueberrymuffinbabey’s page.
Contributor score: 8


Comments ...

 +3  (nbme23#3)
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I gto this one rgwno, utb abdse no het TIT ietsppcevre trsheo mtdeonne,i mebya het ni" rhiet ryarmip ssylnai"a prat fo het nqseotiu si a tip .off hd'eTy start wthi gnucdlini mhet ni eht glnioira spgour and ethn do diltnaaoid sysainal to ytr and seaet otu teh c?iaptm IDK





Subcomments ...

submitted by drdoom(896),
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’srHee eon way ot reeotispsmaoeicl-f-n ard“ecsdee gdd-onhrboney oi”rfnotam: ’mI nto a gib fan fo shit inle of onrsagen,i tub cnthelyilac aaeninl sa a seid gopru sah orme deo*shgyrn for aiotneptl drhegyno ignndbo ntha ngicely:

nl:neaai 3HC—
iclyne:g —H

o,S y,nltc“celi”ah elanain olduw imretp mreo ydnr-deonhogb omionaf,tr whihc mhgti lalwo uoy ot teniaielm atth cio.ech

tTah iads, it esmes otlams psmiliseob ot lure tou (wotuith evry laethincc ldnwekoeg ro semo iepdrovd ieprxmetenal )dtaa thta eth ilsthlgy larerg ineanal osed otn arpmii edynghor nonigdb eenwbte elgolnca clueolmse vai etcisr sapti)a(l f.tceeeeinrnr In pmrlsei rsmt,e ncsei aanleni is glare,r oyu owdul itnkh ahtt ti smtu mooewsh rieertnfe with hte nydg-eonordnbghi hatt osurcc twhi teh itl-ydepw eglicny.

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tltrc*iSy pskgena,i ’ist ont the nbmuer fo gydsherno but oasl hte gtesrthn fo the dlepoi atht aiifsatctel heogdynr :ongnidb a ronghdey ubdno to a ytgonrls greoievcaelntte cemeullo eikl oilneufr wlil ”paepr“a mero vsepotii ad,n uths, hnnodreob-gdy more yolsgrnt wthi a reynba yngxeo moaedrp(c thiw a grdenhoy ecdcnnteo ot aocrbn, for )xm.aeple

teruhrF idena:gr

  1. ieuhpmu/w:e/uht.pt/epdwhig/.ste.lcsdbdh.umlclrohnd/wq
hungrybox  Appreciate the effort but this is far too long to be useful. +26  
drachenx  hungrybox is a freaking hater +  
drdoom  @drachenx haha, nah, coming back to this i realize i was probably over-geeking lol +  
blueberrymuffinbabey  isn't the hydrogen bonding dependent on the hydroxylated proline and lysine? so that wouldn't really be the issue here since those aren't the aas being altered? +  
drdoom  @blueberry According to Alberts’ MBoC (see Tangents at right), hydroxylysine and hydroxyproline contribute hydrogen bonds that form between the chains (“interchain”, as opposed to intra-chain; the chains, of course, are separate polypeptides; that is, separate collagen proteins; and interactions between separate chains [separate polypeptides] is what we call “quaternary structure”; see Tangent above). And in this case, as you point out, the stem describes a Gly->Ala substitution. That seems to mean two things: (1) the three separate collagen polypeptides will not “pack [as] tightly” to form the triple helix (=quaternary structure) we all know and love and (2) proline rings will fail to layer quite as snugly, compromising the helical conformation that defines an alpha chain (=secondary structure; the shapes that form within a single polypeptide). +  
tadki38097  also you can't H bond with carbon, it's not polar enough +  


submitted by hungrybox(1051),
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cpscl,Mooaliayrc qssaoumu clel cnimoarac tsdne to eb etwfifo-h in oloc,r iaingsr mf,ro nad exdntengi into a uhrc.sonb

oucSe:r oiapaiRded

privatejoker  Lol am I the only one that picked Malignant Lymphoma? I thought I remembered Sattar mentioning that metastases are the most common form of cancer to be found in the lung? I tend to pick the "most common" presentation when given so little information to work with +2  
blueberrymuffinbabey  but metastases typically present with multiple lesions so I think at least in exams when it's showing you a solitary lesion, think a primary tumor. +4  


submitted by diabetes(28),
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cna omyoebsd paelxin owh genery octirounpd yb yyogclisls ,ceneadrsi scien eborcai glyslcisoy ceupdro 32 etn rapAP,cemTo ot 2 ent TPA toghrhu aorneciab glscyylsio ?

diabetes  i think the stem should be "energy production by an anaerobic glycolysis " +3  
blueberrymuffinbabey  yeah that's the bit that tripped me up too. i get that there would be increased glycolysis in general to compensate for lack of TCA function but...the fact that it says "energy production by glycolysis" is kind of misleading/confusing. +  
thotcandy  technically, glycolysis is the reaction that happens in the cytosol that generates pyruvate and 2 net ATP. after that it's TCA and Oxidative phosphorylation, which occur in the mitochondria. By definition, glycolysis is anaerobic - which is why they hammer the fact that RBC undergo glycolysis only into our heads. +1  
thotcandy  technically, glycolysis is the reaction that happens in the cytosol that generates pyruvate and 2 net ATP. after that it's TCA and Oxidative phosphorylation, which occur in the mitochondria. By definition, glycolysis is anaerobic - which is why they hammer the fact that RBC undergo glycolysis only into our heads. +  
targetmle  i got it wrong because of this as i thought ATP will be decreased in anaerbic glycolysis, but proabably it was mainly 'glycolysis' is increased +1  


submitted by ls3076(74),
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acn anenoy exanlip hwy (D) maaalstipe is onrcrtcei?

angelaq11  because metaplasia would be a transformation of the normal architecture of the respiratory epithelium to one that does not belong there, in response to chronic irritation. This woman had pneumococcal pneumonia that was correctly (and I dare say promptly) treated, so she suffered an acute rather than a chronic insult. +  
blueberrymuffinbabey  because metaplasia isn't how the normal healing/regeneration response happens in the alveoli. the type 2 pneumocytes serve as stem cells/precursors to both type 1 and 2 pneumocytes so the regeneration is not metaplasia. +1