Quoting Dr Sattar, if an injury or cut is too deep so as the regenerative/stem cells are removed/damaged - then healing can only occur by repair. Thus, in this case, the stem cells of the lung aka Type 2 pneumocytes reside in the basement membrane - so, injury to basement membrane would damage type 2 pneumocytes and would NOT allow restoration of normal lung architecture. That's why maintenance of basement membrane integrity is the most important determining factor to distinguish whether tissue will heal by regeneration (restore normal architecture) or repair (fibrosis/scarring). Same concept can be applied to skin (basal cells) and intestines (crypt cells).
Yuo vhae ot kntih abtou it iths y:wa the tbaneesm mermneab is eth d“caflisnof”g no ichhw a]tsv[tirroee hanilge .cocsru S,o ,esy tmes elcsl eytp( II tc)nmsyoueep uwdlo eb iedlvnvo ni ahtt liahgen ssercop tbu eyht ou’cdnlt stoerer het anrlom cttueicraher “n(o ol)srbiait”eanm toiuthw eht e’nlt‘oeks fo het bsanemte aemmbenr inletlg meht erweh ot go, in waht inodctire to ,rgow whchi yaw si u,“”p e.ct If teh aesbtemn mbeeanrm si drtseeod,y you anc slilt gte gleaihn, but ti ’ntow eb eigarondz eihlnag -- lit’l eb nrgdizidsoae lhnaegi, hchiw dseo otn rappea as rnmalo es.suti idgrieszonDa( elingah is eretbt hatn on aleihgn, tub witothu a ,MB het geerinrngaet lselc ondt’ have any “terdnicoi” and fehteroer cnat’ rtseoer eth lmoanr cr)uatec.iterh
I ouwld ihktn otrneousil vesnovil eht tsme cllse (ypet II p.oescyuet)mn sI the iacntt tensmabe enrmemba the narwes ecbsaue ti sltmii ?erasdp
cna aenony aienxlp hwy )D( aelaitspma si ortec?inrc
submitted by ∗bubbles(79)
It can be re-accessed by making a purchase.
Purchase your membership here
$279$49setaBmen mrnbeema greintiyt is hte ttdrenaemni of lulf ngul cervyeor ofnlolgiw ymupnarol nit.uls
mmaruy:S
1() slso of sbanmtee rbmneaem tntiigery si arclciti in ediintnrmeg hte tni“op of no ”rtue,rn dna tscnbtiuroe ot eth ianyilitb ot seblhsitear mlanor ungl etrrceaituch twih nmpitrooo of f;ssibrio
2() sols of etehialpil cesll, eendhtaioll llcse, nda tnsmaeeb bameernm ertyiting ni alusu ianirtietslt aeinmopun iscaosdaet iwth tiicpdaiho nurymoalp sfribosi dlsea ot rddeseoyt gunl theiaerurctc nad elptepuar rofsibs;i
3)( mnrogasintrf rhtwog cof-taβr si ,acerssyen ubt ton neyrilet tife,icfnus ot pomeort nmeetrpan isrisof;b
(4) tsnrpietse atrn/iaurntnyj/teiiingr si cilictra rfo the iratoogapnp of oiif;sbrs
5() dtcihopiai unyamorpl srsiifob is an exelmap fo a rscopes ltedaer ot eth sersicpenet of na ”nase,)t“g(in cnrocih iali,fnammton nad ;iibfssro nda
6() uuiqne selcl aer cciilrat lclaelur epyarsl in hte eairlougtn of fbso.srii
ti no:acitg/vl6/iC5phpnm/i1/bm.sw//Mecns2wlan:2tc4t4trhio.w..cP
$279$49