anC ensomeo expnila yoprplre owh ew nwko tath tsih ritat wflolso aeinlMdne ecgneits nda is tualosoam eiesevcsr dna utmoeerrhfr ohw hte pnrseat were e?euhrtozygos
I udgeses a olt no sith tsqiunoe nda gto ulcky (:
ymzene iefesycdnci = RA
mgozsohoyu snrceepe of CP"...Y
E:DQ uoosohyzmg + AR = 25%
eimTxnafo has ot eb tdzibamoele iav rfsit sasp msbemltoai ot an vtaeci eotelbitam .efn(xoiend) hTe anitetp hsa dsearcede octtneoarnsicn fo the odmalibeetz rdtpouc iniicadntg htat eht aetitp’sn iarp of yhrtocecom 4P05 elsleal ater’n ezlitnigamob maixnfeto o.cecryltr eTh uoneistq is siknag thaw the checans rea eht srstei sha teh maes e,eotpygn ihchw wluod eb %25 -&;gt- /21 * 21/ = 14/
nvnhetiikgrO cesrwde .em The onsuteqi emts kass rof a chcena rfo a iterss to egt teh aems s,leeall ton ttha esh si shmuooogyz hitw meh.t So I cdkepi 57% instade of tA2 .%5 eht pto of ,it heyt utp *ID2(64 uthoght htta names tath .tp has 4 icpseo fo slatoellwe( from echa aeprnt leik )heAy LTH. vahe ot eamk eqsoisnut peiimsbslo to nsu.ntrdaed
fI soem neo can elph em naddntesru bc im a ibt oecuns.fd I staerudndn teh ghhotut oescrsp nda I idrzleea atth thsi asw na RA eseisda dan I osla tgo eth 1/4 fe,cfeatd 2/1 crairre adn /14 ucnffeated. tBu I csoeh 0% cb I ifduger fi ti swa na RA eaeidss eht 1 dlchi dyraeal dasedise wsa mosuhozoyg catfedfe /(41 defeaf)c.t hciWh aeld em ot hktni atht teh teorh ietsrs aws eerith a crriear or not ceaefdtf at l.al Am I tusj oerv nintghik isth or ma I ton fulyl anndsgtrindeu aswth niogg o?n
oS I etah ihts instuoqe esuebca uoy c'tan ltle atwh het aneptsr' yespgeotn ear. Thsi yzemen eefcdt n'tis hgionetms atht yuo anc tell nthooyplgliaec os ew 'tnca tusj sesuma eht petrnas rea esoertoh.ugnee
tI ylenohts t'sdeo eevn tmtaer fi ti is matlasouo eseverisc or nto cisne ew lony hvae ot wrroy uoatb ozmuosghoy fof is.spgnr reeH si eht ta.mh
easrntP lseobsip gsetenp:oy
A - ;rNmoal a - mab.noarl
omM: aA dDa: Aa tha(w het tnioeuqs si gaun)ssim
mo:M Aa dDa: aa
Mm:o aa a:Dd aA
oM:m aa Dd:a aa ho(w si ot say isth it'sn libsp)?ose
(mMo AA ro aDd AA is iobplemiss icnse hte gnfsifpro anct' be a)a
oFrm eosht nopegety sesibtposiiil we can cctelaual tebret bibteripoisla.
enciS si't pieblsos rof anerpts to aveh yna of eeths 4 eepotysgn ew stju usames hatt ecah tyibolsiisp is .4/1
o:Mm aA + aDd: Aa >-; grsfnopif aa = 14/ uimpt(lly shti by 1/4 nseic 'rewe sauingsm ulqae ylitsiboisp orf ehtor s)oeneygpt &;gt- 1/16
mM:o aa + a:dD aA &tg;- ofgspfnir aa = 21/ g-&;t 12*4/1/ = 1/8
moM: aA + a:dD aa ;>- onigfsrpf aa = 12/ &;gt- 11/*/24 = 8/1
omM: aa + :Dad aa g;-&t nogfsfirp aa = 1 ;g&-t /41*1 = 14/
nTeh we dad lal hte tioriisbalbpe 1tgeho6r/1 te + /81 + 8/1 + 1/4 = 9/61
I nwko eth sotsenui'q asnwre si 2...%5 os I guess tpu 2%5 on hte te.ts BUT fi uyo nwat ot tcuaayll u,trsnneadd tihs is a trbete tmoiroxapipan. The oynl mlbroep is we 'odnt wnok the enge tiirusdbotni fo hte leaells or I can ievg tbrtee tham P:
rySor tsi' gnol dna nocsufngi
eeThr saw a oldurw uoqniest no sh.ti HLA aer aespds ownd to igonsffrp in s.ypteplaho ntareP X has A adn B ,paptehloy atpren Y hsa C and D .aehtloppy eesTh vahe dneiaMenl nt,earhencii i.e. .AR fI teh aetitnp is umzohsooyg ofr yD2Cp6, ahtt samen ttah rtnPea X dan ePrant Y ohbt ahev a oyepltaph hiwt P.Y6c2D i.:e A loapypeth ash ,D26ycp C platehpoy ahs pcDy26
For reh sst,eri etehr is a 5%0 cacnhe mmo saepss ownd her A aho,pylpte adn a 05% ahecnc hte dad psssea dwno shi C l.pypotahe 2/1 x /21 = /41
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$279$49I hhottgu dgreraign sthi oinuqtse as LHA eneg ousbitrdinit n(e .lbok)c
nveE if ew cddsrai higertyven and jstu ihktn obuat het aslt sceeetnn )uisen,q(to fro yan nge,e hencca fo bnsigil hganiv xtcea emas lleeal is %52
ppouses heter ear 4 slellae orf a neeg ni tp,nears ,aA, B, nda b w(hta I anme to ays si all 4 rae idnrteffe in btoh )pantre.s
owN opseusp eno taeudrgh has Ba t.go noTepye heva aetxc asme llas,lee otehr dtaehrgu msut vahe
%05 cnheac fo a n(gamo a and A form itmtlul) hepomdire by%50 neccah fo B nm(oga b adn B rofm ar)thfe
neocidmb opiabltyrib fro yan egen ouwld be 25.%
lsaPee, tpnoi uot yan aftlu in hte srinne.aog
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