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Retired NBME 22 Answers

nbme22/Block 3/Question#23 (reveal difficulty score)
A 45-year-old woman comes to the physician ...
25% 🔍 / 📺 / 🌳 / 📖
tags: biostats

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 +8  upvote downvote
submitted by ∗b1ackcoffee(115)
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I hhottgu dgreraign sthi oinuqtse as LHA eneg ousbitrdinit n(e .lbok)c

nveE if ew cddsrai higertyven and jstu ihktn obuat het aslt sceeetnn )uisen,q(to fro yan nge,e hencca fo bnsigil hganiv xtcea emas lleeal is %52

ppouses heter ear 4 slellae orf a neeg ni tp,nears ,aA, B, nda b w(hta I anme to ays si all 4 rae idnrteffe in btoh )pantre.s

owN opseusp eno taeudrgh has Ba t.go noTepye heva aetxc asme llas,lee otehr dtaehrgu msut vahe

%05 cnheac fo a n(gamo a and A form itmtlul) hepomdire by%50 neccah fo B nm(oga b adn B rofm ar)thfe

neocidmb opiabltyrib fro yan egen ouwld be 25.%

lsaPee, tpnoi uot yan aftlu in hte srinne.aog

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cjdinurdreamz  i dues the mase tcexa aroiensng +
skonys  nSufgiefr fomr sscuesc orve hree eucseba I ujst dear ti sa rhtee one lcuso *6"" and sseh syguhmoooz a.a Tshu reh sesrits hsa a 5%2 hcneac of enigb aa oto caeebsu utennp .easruq soMt prboblay hte nwgro oiclg tbu ,hye we otu r.ehe +



 +4  upvote downvote
submitted by ∗bubbles(79)
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anC ensomeo expnila yoprplre owh ew nwko tath tsih ritat wflolso aeinlMdne ecgneits nda is tualosoam eiesevcsr dna utmoeerrhfr ohw hte pnrseat were e?euhrtozygos

I udgeses a olt no sith tsqiunoe nda gto ulcky (:

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niboonsh  uAomaolst tnmoinDa soerdrdis lusyual serntpe sa etsfdce ni ralcrtutus ,esgne heewr as utoaosmAl vseReecsi erodsirsd sluulay erpnste sa nezmey niiecsde.ifec P540 is an enzyme, os we era brpabyol alinged wthi na suatolamo sevceries drioerds. ermhur,foetr teh iqnuteso atesst hrtee saw a uo"szyghoom secerenp of 50"p......4 nI smauaolot ercvsiese mpbelos,or aspenrt aer luayuls o,tezrushgoye naimgne htat 4/1 of rtieh dsdoki lliw eb fftaeecd aa(k hgy,)usozomo 21/ fo eht iskd iwll eb rrsecai,r nad 14/ of tirhe kdis liwl be tuedfnfc.ae +38
nwinkelmann  Is hsti how we louhds tatcka thsi m?poreb:l sitrF ecul tngsait xiefoednn si etiavc mtoaliteeb of Taoixnmef hslduo meak us gneerizoc siht igdrennu rftsi pssa hpticae CPY054 seiomtlm?ba cnOe ew ownk ttah, teh aftc ahtt hte tiotlaeemb si eeesardc etgssgus an meyenz ,eceftd iwchh si spputeord by npas'iett musgoyhozo yeemnz es.leall Tneh sue teh geaenlr rule hatt enyezm ftcseed aer AR hawsree uluctrrast otpeirn dctseef rea DA nnrheetciia e.atrspt Ocen ew kown teh ear,pttn itkhn ttha otms ocnmom osiratsnsimn of AR esomc mofr wot aerrcir tnp.aser oS nsfrofipg sllleae = 5%2 uymzohogos om,lran 50% osuoyheetzgr eic,rrra adn 2%5 mozoyghosu cde,fatfe sthu ssiter has a 5%2 of ahnvgi eth eams ellalse sa nittaep (i..e yogmhsoozu 405CYP 4*26?)D +6
impostersyndromel1000  ew dah teh ecxat meas tgohuht creo,sps so i oot ma gihnop iths is het otcrcer yaw to rphpocaa ig ett earninsgo dnreif +
ajss  khastn for hist lxi,nntaopea I aotltly otogrf utoab RA trenspat are msto yiekll nmsezye ccnsfiidee,ei sith nikd of emka eth uqoniets resiae fi ouy apaocrhp ti that ,ayw nksaht +



 +3  upvote downvote
submitted by ∗dentist(94)
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  • ymzene iefesycdnci = RA

  • mgozsohoyu snrceepe of CP"...Y

E:DQ uoosohyzmg + AR = 25%

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 +1  upvote downvote
submitted by ∗its_raining_jimbos(29)
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eimTxnafo has ot eb tdzibamoele iav rfsit sasp msbemltoai ot an vtaeci eotelbitam .efn(xoiend) hTe anitetp hsa dsearcede octtneoarnsicn fo the odmalibeetz rdtpouc iniicadntg htat eht aetitp’sn iarp of yhrtocecom 4P05 elsleal ater’n ezlitnigamob maixnfeto o.cecryltr eTh uoneistq is siknag thaw the checans rea eht srstei sha teh maes e,eotpygn ihchw wluod eb %25 -&;gt- /21 * 21/ = 14/

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medschul  oHw od we nkwo the reapstn rae not ymoughszoo +8
yotsubato  ceshnCa are eyth era ont sulnse they dah ro era nutsucioes +



 +0  upvote downvote
submitted by 07chess(3)
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nvnhetiikgrO cesrwde .em The onsuteqi emts kass rof a chcena rfo a iterss to egt teh aems s,leeall ton ttha esh si shmuooogyz hitw meh.t So I cdkepi 57% instade of tA2 .%5 eht pto of ,it heyt utp *ID2(64 uthoght htta names tath .tp has 4 icpseo fo slatoellwe( from echa aeprnt leik )heAy LTH. vahe ot eamk eqsoisnut peiimsbslo to nsu.ntrdaed

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 +0  upvote downvote
submitted by g8427(0)
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fI soem neo can elph em naddntesru bc im a ibt oecuns.fd I staerudndn teh ghhotut oescrsp nda I idrzleea atth thsi asw na RA eseisda dan I osla tgo eth 1/4 fe,cfeatd 2/1 crairre adn /14 ucnffeated. tBu I csoeh 0% cb I ifduger fi ti swa na RA eaeidss eht 1 dlchi dyraeal dasedise wsa mosuhozoyg catfedfe /(41 defeaf)c.t hciWh aeld em ot hktni atht teh teorh ietsrs aws eerith a crriear or not ceaefdtf at l.al Am I tusj oerv nintghik isth or ma I ton fulyl anndsgtrindeu aswth niogg o?n

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rush  you have ot tnhik aobut ehca hicdl udinilay,ldiv d'osnet arttme atwh het issbling h.ave The eoqtisun setsat hwat era the osdd fo teh dlchi gtgtine eht d.eesias So salgesdrre fo het ehtor slbinisg it illts is Mmo ()2/1 dad 1/2)( cwhih smeka ti /14 AR +
titanesxvi  tBu how od we onkw htat eht pnartes aer uotyogerszeh fro teh ttominau +
need_answers  ew wkon that teh asnpert eavh ot be shtgreeoyouz aA X aA euasebc on a 2x2 bleat, eht lyno ayw hte traegdhu dcoul be sgyzuoomoh rof na RA is yb gnhiva othb rsentpa eb riarcesr A)a( so eth eqoistun wsa snigak wtha rea eht hcsncae eth steirs sha eth asme llsalee )(aa nad rethe si ynlo a 5%2 fo ghnvia eth same lel.esal +



 +0  upvote downvote
submitted by timekeeper36(0)
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oS I etah ihts instuoqe esuebca uoy c'tan ltle atwh het aneptsr' yespgeotn ear. Thsi yzemen eefcdt n'tis hgionetms atht yuo anc tell nthooyplgliaec os ew 'tnca tusj sesuma eht petrnas rea esoertoh.ugnee

tI ylenohts t'sdeo eevn tmtaer fi ti is matlasouo eseverisc or nto cisne ew lony hvae ot wrroy uoatb ozmuosghoy fof is.spgnr reeH si eht ta.mh

easrntP lseobsip gsetenp:oy

A - ;rNmoal a - mab.noarl

omM: aA dDa: Aa tha(w het tnioeuqs si gaun)ssim

mo:M Aa dDa: aa

Mm:o aa a:Dd aA

oM:m aa Dd:a aa ho(w si ot say isth it'sn libsp)?ose

(mMo AA ro aDd AA is iobplemiss icnse hte gnfsifpro anct' be a)a

oFrm eosht nopegety sesibtposiiil we can cctelaual tebret bibteripoisla.

enciS si't pieblsos rof anerpts to aveh yna of eeths 4 eepotysgn ew stju usames hatt ecah tyibolsiisp is .4/1

o:Mm aA + aDd: Aa >-; grsfnopif aa = 14/ uimpt(lly shti by 1/4 nseic 'rewe sauingsm ulqae ylitsiboisp orf ehtor s)oeneygpt &;gt- 1/16

mM:o aa + a:dD aA &tg;- ofgspfnir aa = 21/ g-&;t 12*4/1/ = 1/8

moM: aA + a:dD aa ;>- onigfsrpf aa = 12/ &;gt- 11/*/24 = 8/1

omM: aa + :Dad aa g;-&t nogfsfirp aa = 1 ;g&-t /41*1 = 14/

nTeh we dad lal hte tioriisbalbpe 1tgeho6r/1 te + /81 + 8/1 + 1/4 = 9/61

I nwko eth sotsenui'q asnwre si 2...%5 os I guess tpu 2%5 on hte te.ts BUT fi uyo nwat ot tcuaayll u,trsnneadd tihs is a trbete tmoiroxapipan. The oynl mlbroep is we 'odnt wnok the enge tiirusdbotni fo hte leaells or I can ievg tbrtee tham P:

rySor tsi' gnol dna nocsufngi

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 +0  upvote downvote
submitted by fukprometric(3)
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eeThr saw a oldurw uoqniest no sh.ti HLA aer aespds ownd to igonsffrp in s.ypteplaho ntareP X has A adn B ,paptehloy atpren Y hsa C and D .aehtloppy eesTh vahe dneiaMenl nt,earhencii i.e. .AR fI teh aetitnp is umzohsooyg ofr yD2Cp6, ahtt samen ttah rtnPea X dan ePrant Y ohbt ahev a oyepltaph hiwt P.Y6c2D i.:e A loapypeth ash ,D26ycp C platehpoy ahs pcDy26

For reh sst,eri etehr is a 5%0 cacnhe mmo saepss ownd her A aho,pylpte adn a 05% ahecnc hte dad psssea dwno shi C l.pypotahe 2/1 x /21 = /41

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