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Retired NBME 20 Answers

nbme20/Block 2/Question#41 (reveal difficulty score)
Purified serum antibodies elicited by ...
Proteins X and Y express the same epitopes 🔍 / 📺 / 🌳 / 📖
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 +11  upvote downvote
submitted by usmile1(154)
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If ouy olko at Uowdrl qtoeiusn ID 22919 it has a fdenolrwu nolntaepxai rfo ihs.t fI ythe raehs hte aems sto,peiep it lwli eahv a wwroadnd le oIfp.s yeht rhsae none of eht saem ,etpesopi hte inel lilw be ohilatornz csosar eth hrpga tdaiiin(cgn on nahecg as teh ntaoum fo Y addde sri)cesnea

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eacv  mog !Y!ES kastnh owdrlU I otg ti cotrerc! xcatlye shit qx adeks eht cxtea ispeotpo ihtng! Hhahaa I ovedl it !! +9
pg32  Evne etafr aegrdin het dorlUW a,nxltoepian I am sltil nto eurs ohw the nwrsea ahtt resad, r"ineotP Y esrxseeps lal of eth stioppee dseerxesp by porenti ,X tbu etoprni X dsoe .n.".to si erctrn.ioc saBde no the rph,ga I ondt' see a ywa ew nac luer uto htat erwans eccoih adn it ssudon mero kilyle than tohb X and Y ainhvg teh EATCX ESAM .seetppoi nCa oanney ianl?exp hatW dlwuo eht gphra okol elik fi eth qotued aernws icoehc asw tcr?erco +3
69_nbme_420  fI oyu eamk up na epxmale hwit nb,rsmeu it lrayel le!phs oP“etrin Y rsxespees lla fo the ppoitees pexesdser by X, but npotrei X oeds ton erxepss lla fo pteoeips eeersxsdp yb onreitP ”I. fY we say epotirn Y sha teepsopi 1, 2, dna 3. nThe ePriotn X sha ieoesppt 1 and .3 heTn we acn alecrly ees teh siiloahrntep hte OMNTAU of Y adedd teearvli to X uodnb duolw TON eb in.lera dteSta rnteoah yaw – ew nede na lteanlnoepxiy rmeo tanuom of Y ot ECYTLLOMEP nuindb X and erterohfe rethe odwul not eb a eno ot neo pniotdice in het irmaairplhgS gloic alipsep for het enrasw eoihcc ttah setsat ronet"ip X rxseeesps all fo eht iotpespe xspseered yb nteoipr ,Y tub tnoriep Y deos not xessepr lal fo the pitoespe xsredseep yb tpnireo X...gE fI rnoeitp Y sha esiptpeo 1 nda 2. ndA ipetrno X has espoitep ,1 ,2 adn .3 eeHr ai,gna we heav diseitasf eth eanswr eccisho idonntoc,i nda on taetmr woh hucm ew esranice trieopn Y, oetinrp X liwl tlisl aevh eeoippt 3 obund ni shit .scea +5
69_nbme_420  usJt ot lcaiyfr rfo eht tfsri eincsa:ro We aehv 3 pietoesp no Y, dan 2 pstipoee no X. athT ,smnea sminugas eth ptsepoei rea lal psntere ni ueqal suamt,no fi I add 030 smgar of niptreo Y ot eth otloinsu - nloy 020 msgar lwli nidb torpeni X. NAD NOLY 002 ragsm of ptneroi X nca be dounnub. peoH eht msurben ehpl! +1
fruitkebabs  Fro ybnyoad istll csutk on oPetr"ni Y eseseprsx all of het psoepite dexessepr by tioprne ,X tbu toinrep X does o",nt hgltoauh stih meteatstn yma eb urte, hrtee si tno gunhoe imiafootnrn in the unoqiset to eprvo hsit. We nkwo rfo cfat thta ceasbue eth tuomnA of laledbe X dbuon raceehs 0, ta eht rvey ta,sle ertniop X dna Y pesrxse eth mase eepitosp enics at a ncreita con,cnenotirta Y si lbae ot plymclotee ladiepsc all X morf eth syme.st Tsih tsdeno' lxecedu het spsibltiiyo ahtt eethr aym be rxtae tipeeosp on ,Y but ti es'nodt evopr ti three.i +4


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 +2  upvote downvote
submitted by amarousis(27)
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os owh udolw eht graph oklo fro poeitnr x eeexsrpss all fo the pisetope rspedsxee by oepntir y, ubt iroepnt y eosd otn rxeessp all of hte peotepis peesxsdre by onpirte x?

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drw  tnhe smeo tni-Xa tnnaco tacorlee to Y vnee Y is aeddd at wrteeavh ighh os.de ta shti ,inconoidt het inel anc neerv chuto teh .a-Yxis n o the rntayo,cr fi Y esrsxpe lal tepispoe no eht ,X utb X esod tno seesrxp lla ppseotie on the ,Y atth masen esom Y iseotepp aer ton eesn on X. ta shti ndooinct,i I odtn' okwn wtah wlli eb teh ilen kdooel .lkei +1
medbound57  I hkitn atth hte lin'se wwdrdano lesop loduw be ,psteere nscei Y hsa omer ssite taht het anyiobtd luwod nbdi .ot +

why this is wrong- prtoein y has all epitopes of x and protein x does not have some epitope


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 +1  upvote downvote
submitted by usmleboy(19)
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An ynabtodi can yonl irgczeeno a nleisg oepeit.p Senci ew see eth orme Y ddeda dales to elss X db,nuo then uoy nca esnoar teyh resha het asem bdgniin i,tses dna Y si rirpewonoevg .X

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srmtn  GMO hist is hte anores hy!w tankh !o!y!u +
srmtn  btu eetrh era neaisodbit ttha anc tractnei ithw 01 p..p.lxemtaoespeei ...MIg sryor ogt lots inaga (: +
chj7  roF oeanyn lltis genlildw no h,tis the sroecsp teyh takl uabto in eth sneitqou tmse is yisbplso loyaolclpn u(sth the ssieu fo eumipltl s)epepi.ot +


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submitted by rhizopusmucor(1)
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I nofdu s,hit I hintk it visge nadik fo an xp:aeolaintn If the eeigsronsr of glo 'A/(()A -1) on log- B si rnilea ihwt a oslpe fo -1, hent stih taesiicdn ttha eht gnmstaniao si mtteipvceio dan by inintfdeio het itogans and insaottang atc at teh ESMA getorinocni sstie. So blsaalyic teh erom yuo add ,Y het elss X si nduo,b icwhh mnase teyh veah a mesa lausttucrr otencmnop (eoeptpi) dna stum act no eth mase ste?i 'tnDo owkn fi ihst asekm nee.s.s.

purhidnayutbplssetat//g/ihhstifn1/gp./dmltoh~sdc/cu.jsc.bbem:aoe

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 +0  upvote downvote
submitted by stepwarrior(29)
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thsi qienostu wsa rtute S,B btu het way I ueisitfdj s"ema seeo"ptpi was atth ti aisd i"n hte xoenttc fo -irnmuaset X", e,i.. chhiw soeepitp uwlod ehav bnee oedevldpe in eth txntcoe fo eth indbtaoeis nsepr.te s'It ulyeikln thta -tnaiX bietndoias wdluo bdni to opetipes on Y thta tn'aer on .X tBu uyo dcolu ergua theer ear aehocrlteit pieeptos no Y ahtt oudcl be dobun yb tneohra ioatdbyn atth sendto' xstei in isht nseao.irc

eyrV ndrwa uot dan otko me 5 muitsne ot lyaucatl efguir out on het ts,te eolnshyt a twaes of mtie in ym oop,nini btu trhee uyo .go

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submitted by peachespeaches(2)
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eaBcues it si a htsritag arnwwddo ep,lso oyu can slao llte tath Y adn X rae obnud ni rsimial sywa yb bset.nidioa hWat edtietfeisanfr eht t,wo e,hnt 'snit teipeop bginndi bcp,ailtiya btu eht nocnotnariect. lAl lsee qleau htiw nigdinb s,iets emro Y wiht na cnughgnian ntouma of X lwil adel to lsse X ond,ub ni a :11 rmaenn.

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submitted by ilikecheese(46)
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iHgh X is obnud nwhe olw Y si addd,e dan low X is bundo wenh Y is doa.dS ed YMEAB heyt rea cgopmient rfo eht aems binnigd osio/ttpeepp eud ot htis tpiearhoisnl (eoi=ppet nydbaito gindibn ???t ?i?)?s?e???

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submitted by breis(56)
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uyor sgsue si as odgo sa ........i...m..e................................n........................

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nala_ula  I nteps os lgno on sthi itneqsou adn as.me.. hahhaa +


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submitted by am.cassandre(0)
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nRa osrsca a tosniueq misialr ot shti ni hetonar nqieostu anbk. In hatt n,utosqei reteh asw no enahcg as hte ntcnnroticoae fo het nwe tripoen asw dd,eda wichh etanm taht eht wot renpsoit ddi otn rhsae rsmiila epi.epsot In tshi tunei,soq hte yntidabo is jsut yrigtn ot bidn tis ,otpepei so dadgni mreo ro y saemn lsse binnidg of roentpi x abusece hte aobdinty fsorav the torinspe the e.ams

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This question tests the basis of competitive inhibition. if they express the same epitope, they will bind the same receptors. Adding more X will mean less binding of Y, hence the downward slope.


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