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Retired NBME 20 Answers

nbme20/Block 2/Question#41 (reveal difficulty score)
Purified serum antibodies elicited by ...
Proteins X and Y express the same epitopes 🔍 / 📺 / 🌳 / 📖
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 +11  upvote downvote
submitted by usmile1(154)
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If uyo kool ta wUolrd etuiqson ID 12299 it hsa a rudownlef tnxpaealoni rof sith. If ehyt eashr eht esam opspeti,e it lwli vhae a nwdrodaw .pf eIsol ehty rheas none of eth mesa eposep,it eth eiln liwl eb rnaohtizol sarcso the rhpga atgdin(cini no nhaegc as eth namout fo Y ddeda s)eeinsrac

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eacv  gom !!ESY ansthk dowrUl I otg ti !roerctc atxleyc sith xq sdake het cexta tesppioo g!htin aHaahh I dvleo it !! +9
pg32  eEnv farte gndaeir eth oWdUrl exnotnila,pa I am tisll otn eusr woh teh earsnw atth ,sdrae Pioetn"r Y exseesspr lal of teh epsopeit esxpesrde by rtpenoi X, tub erotpni X sdeo n"..to. is ncoicrter. eaBds no eth ,pgahr I dnto' ese a wya we anc rlue otu ahtt nearsw hioecc dna ti udosns reom yllkie tanh ohtb X nda Y ivhgna het TXAEC EMAS ptose.pie naC eoynan eani?lxp thWa lwuod the pgrah lkoo ilke fi the uedotq wansre ohecci was rtcoc?re +3
69_nbme_420  fI ouy amek pu an pmaeexl ihwt ue,mnsbr ti yearll lh!pse “nPetroi Y sesperesx all fo the ppoestie rxspdeees yb X, but piertno X deso tno epxsser lal of iosetppe edseresxp by oniretP IfY ”. ew yas oeptinr Y hsa eotpseip 1, ,2 nad 3. henT oitenrP X sha opptisee 1 nad .3 eThn ew cna cllreya ese hte pnasiiheortl het NOMUAT fo Y edadd reltviae ot X bdoun oulwd TON be raei.ln eattdS entraho wya – we ndee an ylaexltneinpo orem utnoam of Y ot ELOMCYTELP ibdnnu X dan heteeofrr three lwdou ton be a eno ot one tiepniodc ni hte lrahpiigSma r ciogl spilape orf teh earwsn cihceo htta stesat rten"pio X ssrexseep lla fo het ieopspte srsdeepxe by ternpoi ,Y but preniot Y dose otn sxeersp lla fo eth sepeotpi prexessed yb ritenpo .X..Eg If epnirto Y ash teieopsp 1 dan 2. dnA etiprno X hsa poistepe ,1 2, and .3 Hree nag,ia ew aevh dsisfatei teh srnwea cocshie ,oidncniot dan on atmret how cuhm we ecesnari oineptr Y, roipnte X lilw istll heav poeipte 3 onubd ni siht .seac +5
69_nbme_420  tusJ to ylfarci rof hte itfrs oraesic:n eW aveh 3 speeipot on ,Y nad 2 otppeesi no X. Taht sna,em nsgimsua eth pitpeeos era lal ersnetp ni eaqul ostnuma, if I dad 030 gsrma fo erptnoi Y to eht lntsoiuo - yonl 200 smgar lliw ndbi poitenr X. ADN NYOL 020 grsma fo rotneip X anc be .uboundn poeH hte nmseubr hle!p +1
fruitkebabs  roF ynodbya stlli ktsuc no rPeito"n Y serxsspee lla fo het tpioepse sdperexse yb pnreoit X, ubt erniopt X edso not," holtuhag stih nttatseme yam eb ,rteu terhe is otn unoehg irmanoinotf in hte ntoieqsu to prvoe hsi.t We wkno fro tfac ahtt aseecbu het numtoA of edblela X bnodu ershcae ,0 at the yvre ,eltas opretin X dna Y seexspr the emas esotpeip seinc ta a icreant ortnocnin,acet Y is abel ot etlpmolcye eiaspcld lla X orfm het myte.ss iTsh td'onse leucedx eth ltisoiiybsp htta trehe may eb traex toseipep on Y, utb it ned'tso poevr it .rhieet +4


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 +2  upvote downvote
submitted by amarousis(27)
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so owh wdulo teh gahrp ookl orf rionpet x psrxsseee lal fo het iptpeeos xseederps yb eonprti y, tub toerpin y does ont esxespr lal of eth eesotppi drespexes by eotirpn ?x

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drw  enth eosm Xni-at atoncn raloeect to Y vene Y si dddea at awhtreve hhgi eod.s at hsit tni,oncoid teh neli acn neevr otchu the ai-sY.x on hte rtaonr,cy fi Y sepserx lla pseeiopt on hte X, tub X soed not xpseres lal tspeioep on teh ,Y tath smaen meso Y ieppoets are not sene on .X at tihs dniotoic,n I 'ndto wonk atwh lwli be the niel dekool elik. +1
medbound57  I ikthn ttha eht nsile' wadnwodr posle lowdu eb ete,serp iesnc Y sah omer siets ttha hte btdianoy douwl dbni .ot +

why this is wrong- prtoein y has all epitopes of x and protein x does not have some epitope


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 +1  upvote downvote
submitted by usmleboy(19)
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nA nibatyod nac noly nrzceiego a ilsegn tpeo.pei cinSe we see eth orme Y eaddd asdel to lsse X u,bodn ethn uoy cna eranos hety eahsr het msae gdbiinn ietss, nad Y is eirowgrepvno X.

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srmtn  MGO sthi si het aroesn h!wy tnhka y!!uo! +
srmtn  btu erhte rae dtioasiebn atht anc teciartn wthi 10 oaielms.pte.pxe.pe .M.g.I ryrso tog ltso gaain :( +
chj7  orF neyona sltli wdellnig no isth, hte eopsrsc ythe tkal uabto ni the qonuties smet si psbyliso pncoayloll sthu( eht esuis fo lpeuimlt )eoepipst. +


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submitted by rhizopusmucor(1)
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I dofnu sti,h I tkhin it svgie inakd fo an n:opanieltxa fI hte gnsreersoi of olg A(/)'(A -1) no lo-g B is nlarie itwh a leops of ,1- tehn htsi tasideinc hatt eht notagsinam si tepcemvoiti dan by otnndiifei teh sintaog dna atigtnnsoa tac at teh ASEM iiogentrcon sties. So lcabylais teh eomr uoy dda ,Y het sels X si ,nudob whhic mneas ehty aveh a easm trsturualc mpocneton epp)(toie dna mtus cat on het msae est?i noD't ownk fi siht sakem s.e.es.n

lucdetbdt~mb1sss.hiemba//pou/.nysthoeiapg:/frtcg.nsiaj/luhhdtcp/

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 +0  upvote downvote
submitted by stepwarrior(29)
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hsit uioqnest aws erttu B,S btu hte yaw I estdjfiiu sam"e toeie"pps aws hatt it dais i"n the otntcex of etr-nasumi ,X" ,e.i. whhci pepietso uowdl eavh nbee pevldeedo ni eht noxettc fo eht bienaidots rtesp.en ts'I lnukyiel ttah nXtai- aindobeist luwdo bdin to epetpiso no Y thta rta'en no X. Btu yuo uldoc auger htere rae etrthecioal epetspio no Y htat loduc eb nbudo by enrhtoa datnobyi ttha odt'nse itsxe ni iths cnrsi.oae

Vrey wndra uto nad took em 5 mstineu to cyaaltlu eifgru out no hte ets,t eohnylst a atwes fo etmi in my ponnio,i tbu eethr you .og

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submitted by peachespeaches(2)
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cuesBea it is a tihrgsat wanodwdr pl,soe uoy can aslo eltl taht Y nad X are bonud in amrisli wsay by enas.dotiib htWa dtesfeiaritefn het t,ow nt,eh tni's itpoepe iidnbgn ca,ypbailit utb the cianncn.rootet llA eesl qleua hitw bdgnini sits,e moer Y iwth na nnighngcau notaum fo X liwl leda ot ssel X o,budn in a 11: nanm.er

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submitted by ilikecheese(46)
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igHh X si obund hwen wol Y is edadd, nad wlo X is nbuod hwne Y is Soedd. da YMAEB tyeh aer oecntipgm fro the meas igbdnni totsiepep/op ued to thsi tonisailpreh (o=tpiepe atoniydb dibngin eti????)s??????

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submitted by breis(56)
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ryuo gsues si sa oodg sa ................................................n.........m.....i...e....

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nala_ula  I snetp os ongl no isth qitnuoes adn sa.e..m haahah +


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submitted by am.cassandre(0)
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nRa sacors a qitseuon mrilasi to thsi ni etnarho iunsoqet .bkan In that tqsno,eui heret was no ehcgna sa teh croaoecttnnin of hte enw eiontrp aws ddeda, chwhi metan hatt hte owt estonrpi ddi tno ashre irmslai sipt.epeo In sthi i,ntouseq teh dtyanboi is jsut rinytg ot bdni its eptoe,pi so igddan emro or y nseam lses gnnibid fo rinoetp x eabescu hte botyanid ovrsaf eht peisront the m.aes

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This question tests the basis of competitive inhibition. if they express the same epitope, they will bind the same receptors. Adding more X will mean less binding of Y, hence the downward slope.


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