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NBME 20 Answers

nbme20/Block 1/Question#40 (51.0 difficulty score)
Monoclonality of neoplastic cells in ...
X chromosome-linked isoenzymesπŸ”,πŸ“Ί

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submitted by hayayah(1100),
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osiaalpNe is new tessiu orwhgt tath is r,dgeaneultu revisli,reber dna nolon.cmola

tioCllayn acn eb imendtdeer yb uesotp6lhah-ge-ospc hnedregedaoys 6DG)P( yeenzm rfsom.ois G6PD is lndie-kX.

*rFo orem nmnitafoiro hkecc tou C.h 3 loaipNsae ni hoPatam

hello  This is great, thank you. +5  
breis  Pathoma ch. 3 pg 23 "Basic Principles" +9  
charcot_bouchard  Shoutout to Imam Satter! Without him this question wasnt possible for me to answer in 10 sec. +14  
fatboyslim  Clonality can also be determined by androgen receptor isoforms, which is also present on the X chromosome (Pathoma Ch. 3 Neoplasia) +2  
lovebug  @fatboyslim thanks for reminding! +1  
makingstrides  Just to make sure I got this right, because this is neoplastic and its monoclonal, you want to look at the isozymes to determine its clonality? +2