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NBME 20 Answers
A 50-year-old man comes to the physician because of ...
Just adding support to the above explanation:
do all azoles or just itraconazole only requires an acidic environment to be absorbed?
Its not a cytochrome question. IK because i go t it wrong
Azoles, as a class, are CYP450 inhibitors [fungal > human; to prevent conversion of lanosterol to ergosterol]. Justget is correct- a ↓pH is needed for absorption and PPI/H2RA/antacids are contraindicated.