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Retired NBME 20 Answers

nbme20/Block 2/Question#41 (reveal difficulty score)
Purified serum antibodies elicited by ...
Proteins X and Y express the same epitopes 🔍 / 📺 / 🌳 / 📖
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 +11  upvote downvote
submitted by ∗usmile1(154)
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fI yuo kloo ta lUdorw nqseouit DI 21992 ti ahs a odrwfeunl plinxaetnao rof ihts. f I tehy arseh eth aesm p,eeotisp it iwll aevh a wnorwdda lspeof .I teyh arhes none of teh seam optpesei, eht lien ilwl eb toizaohlnr rosasc het hapgr iadntignc(i no agnehc as eth nmoatu fo Y aeddd neiessac)r

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eacv  ogm S!!EY knstha drolUw I ogt it ccr!etor atxcley htis qx aedsk eht excta eppitoso !inthg hHahaa I veldo ti !! +9
pg32  vneE erfat neargid eht lUWodr ioaa,ptnlenx I am ltils ont seur who hte awnres that ,esdar t"erPnio Y eessxpser all of eht epopteis dxsrspeee by eritonp ,X ubt etrnpoi X sedo no."t.. is irtccneo.r Bdase on eht rahgp, I t'dno ees a ayw we nac rleu tou tath snwaer eoichc dna ti sundso rmoe lkiyle hnta obht X nad Y nghiva eht TCEXA ESAM ip.eespto Can eyonan axn?plie Wath would eth ghpra loko leki if eht tqeduo nwasre oceich wsa rcoct?er +3
69_nbme_420  fI uyo amke up an emalpex thiw bun,rmse it llaery eshp!l ntor“ePi Y expsessre lla fo hte etosippe esrpsedex by ,X btu otpinre X soed ton srpsxee lal fo pispeeto esexsdpre by ieonrPt f I”.Y we asy ptrioen Y ahs ieppesto 1, 2, and 3. Tenh rinPteo X ahs tpopisee 1 nad .3 eTnh ew anc earclyl ees the linitharsope hte AONTUM fo Y daedd eeilvrat ot X obudn uoldw OTN be i.erlna tdtSae rntoaeh ywa – we dnee na oaeieylntxpnl rmoe muotna of Y ot PLYMLOECET indbun X and efoeretrh rtehe dluow ont be a oen ot oen idetnocpi ni teh mSailhiaprr g olicg epasipl fro the srwnae ecoihc htta atests "irnptoe X spseersex lla fo eth pipeotes xeepsedsr by orpetin ,Y but eripont Y dose not erspxes all of teh peotipse eesxerpds by nretoip .Xg.E . If eiprton Y hsa epptosei 1 dna .2 nAd prtneoi X ash soeppeit ,1 2, and .3 rHee ,aiang ew veah eiastfdsi het anresw scoheic noi,tdinco dan no eramtt ohw uhmc ew aecrseni enrpoit Y, ptorine X liwl ltisl eavh etpoepi 3 odbun ni htsi .asce +5
69_nbme_420  stuJ to criafyl rof hte fstir ne:irasoc We veha 3 pepiotes on ,Y and 2 oeipetsp on X. tTah nsm,ae isnguams eht eetsppio are lal rnsepet ni ueqal sunmta,o fi I add 003 mgars of ptenrio Y to the otuonlsi - lyno 020 amrsg llwi bndi prteion X. NDA OYNL 020 rmsag fo opnietr X cna be nunu.odb opeH the msnbrue ep!hl +1
fruitkebabs  roF dbyynao sillt cukts no ort"Pien Y sxesresep lla of teh pestpieo exsdpsere by teinopr X, but proneit X osde no"t, toualhgh itsh eetstmnta aym be ,eurt rteeh si otn ugonhe afoiornmtin ni eth inesqtuo to vreop shit. eW nkwo fro fatc htta bseueac eth nAmuot of eeldbla X undbo recesah 0, ta the rvye tae,sl tpenrio X adn Y sprsxee eht asem potpesei cesin ta a nrticea neit,rnncacoto Y si labe ot tyceeploml dlcepasi lla X fmor eth .mtesys Thsi et'nsod exdcuel het lypiostibis ahtt teerh amy be eaxtr psitopee no Y, utb it one'dts preov it hieer.t +4


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 +2  upvote downvote
submitted by ∗amarousis(27)
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os who owudl the gahrp okol for tireopn x ssrxeseep all fo het tpsoepei xedspesre yb neiortp y, tbu itrpnoe y eods ton srexpes lla of hte iptesepo rexedessp by ointerp x?

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drw  nhet meos aX-int onncta eoclarte ot Y even Y si dadde ta rhavetew ihhg sd.eo ta htis ,dinnoitco eth nlie acn rvene uocht het s-xYi.a n o eth rrc,ntaoy if Y peresxs lal soteppei on het ,X tbu X esod tno sesrxpe all ispeepot on teh Y, ttha neams meos Y itospeep ear otn nese no X. ta ihst cd,noniiot I 'dotn nkwo htaw lwil be eth lein edookl iel.k +1
medbound57  I ihntk atht eth 'elsni rddwnowa lpsoe wdluo be pt,erese inces Y hsa remo setsi atht eth bidtyaon owudl ndbi .to +

why this is wrong- prtoein y has all epitopes of x and protein x does not have some epitope

+1/- prudvi96(0)

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 +1  upvote downvote
submitted by ∗usmleboy(19)
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nA itbnyado nac noly reecnogzi a esglin otpeip.e icnSe ew ese eht mero Y eaddd adsel to sels X o,bdnu ehnt uyo cna sonear yteh hesar hte seam idnnbig tes,is dan Y si nrwovrgioeep .X

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srmtn  MOG hsit is het asnoer !hwy htkna y!!u!o +
srmtn  but eethr era osaiibdten ttha can ttnaicre htiw 01 eml.isept.xo.epaep M..I.g yrsor tgo lots naagi :( +
chj7  oFr yaonne lslit dilelgwn no hs,it eht spsroce they takl butoa ni teh itquenos tsme is ipbsolsy yaolllnpco (thus teh uiess fo mlutleip etis.)ppeo +


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 +1  upvote downvote
submitted by rhizopusmucor(1)
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I ufndo hi,st I hktni it eisgv kiand of an txp:lionaane fI hte enrsiregso of ogl A)'((/A )-1 no glo- B si rilean thiw a lespo fo 1-, htne stih csteanidi ttah the stnaamgino is ocevtpiemit dna yb nofntiiied eht tsgonia nad ntgtioansa cat at eth MSEA ornnotigeic isste. So asiacyllb eht orem uyo dad Y, eth less X is ou,dbn chihw ansem htye vhea a mesa autrutcrls otcomepnn )p(toepei nda stum cta on hte aems ?iste nDt'o wonk fi hsti kmeas sen..e.s

ilres/njs/hf.pigpabte/b/dou.hcsc:/pitcsnteh1asmobthu.g~/taddylmu

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 +0  upvote downvote
submitted by ∗stepwarrior(29)
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this qeioutns saw euttr S,B tbu eth awy I fteiusdij maes" spioeept" wsa that it iasd ni" teh oxntcte of sniremtu-a X", .e,i. hcwih epiestpo wdluo aevh been dvoeeplde in eth exottcn fo het ibstidenoa eepn.srt Is't iyeullkn thta -nitaX tbdasinieo dlwou dbin to ppeoiest no Y hatt enta'r on .X Btu you odclu gurea rthee aer hieotecralt spioeetp no Y htat clodu be dunbo by onaehrt ibyadnot hatt nsetdo' estix ni hsit iarc.neos

ryeV adnwr uto and took me 5 smientu to acyatllu reiugf uto on hte t,ste thlnysoe a ewats fo meti in ym ,npinooi but htere ouy g.o

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 +0  upvote downvote
submitted by ∗peachespeaches(2)
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Beacseu ti si a tgrtahsi oawwrdnd s,eplo uoy can aslo tlle taht Y and X rea dnubo ni rimisal ayws yb enbad.istio tWah aeerdntfesiift the ow,t nt,eh t'nsi peeipto bnindgi icytaip,bla tub eht te.citrnanonoc llA seel ualqe ihtw nibgnid et,sis remo Y wtih an hinaungcgn otmuna of X lwil aeld ot slse X buon,d ni a 11: mn.nrea

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 +0  upvote downvote
submitted by ∗ilikecheese(46)
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ihgH X si dbonu when wlo Y is dda,ed nad lwo X is nodub when Y is dddS.eo a EBAYM eyth era nmtpoceig for the asme innbgdi eptepiopso/t eud ot hist irihlstpneao t(iepoe=p tbiaynod idibnng s????? ?i??t?e)?

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submitted by ∗breis(56)
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uyro usesg si sa oogd sa ..e....i....................................m..................n.........

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nala_ula  I tpnse os logn on tihs qesotuin adn .se..ma hahhaa +


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submitted by am.cassandre(0)
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Rna crsaso a nteusioq lraimis to sith ni hrenaot teuinsoq nkb.a nI ttha stouiqne, ereth wsa on gcahne as eth concninetaotr fo het new poterin aws dded,a whcih aentm thta hte otw operitsn ddi ont ehsar lsaiimr .poisetep nI stih o,stiqenu eth btiyndao is usjt itgryn to dinb tis ,eioptpe os gndiad more ro y manes ssle ginibdn of pneirto x eeubasc hte yabnoidt sfvoar the onpsreti eht .mesa

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This question tests the basis of competitive inhibition. if they express the same epitope, they will bind the same receptors. Adding more X will mean less binding of Y, hence the downward slope.

+5/- latdorsi(4)

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