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Retired NBME 20 Answers

nbme20/Block 2/Question#41 (reveal difficulty score)
Purified serum antibodies elicited by ...
Proteins X and Y express the same epitopes 🔍 / 📺 / 🌳 / 📖
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 +11  upvote downvote
submitted by usmile1(154)
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fI ouy olko ta Uwrodl entouisq DI 92912 it sah a oneulfwdr lxapniatone rof tsi.h fI eyth seahr hte meas ,peietspo ti lliw vhae a wnodarwd op. flIse tyhe hares onen of hte amse esp,opiet het ilne lliw eb rozinhalot ssraco hte grpha niinctgdia( on gnhaec as hte auotnm fo Y daded sa)rcieesn

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eacv  gom Y!SE! tsknah dlwUro I gto it ccrrot!e ctleayx tsih xq akdse the ectxa pospeito ignh!t aahhHa I oldev ti !! +9
pg32  enEv teafr idergan eht rlUoWd aei,atlnonxp I ma litls ont sure ohw het wensra ahtt ,rsead nteoPr"i Y esspeserx lla of eht ppeeisot dprxsseee by nrtoepi ,X tub treinop X odse n.."to. si teo.ccnrir eBdas no eht pahgr, I tnd'o see a ywa ew acn rlue uot ahtt aswren ichoce adn ti ssduon erom yillke than bhto X adn Y inghva teh AXETC SAME eso.pptie nCa nayoen x?leipna Waht oluwd hte arhpg kloo like fi eth odqteu earswn icceho aws ocre?rtc +3
69_nbme_420  fI ouy kame up an meepxla hiwt u,rebsmn it lreayl pels!h ro“intPe Y sessxerep lla of het ipteospe dpesxsree by X, but retipon X dsoe nto xspseer lal fo sppteoie sdpxeeser by tPronie fY. ”I ew ays roieptn Y sha estpopei 1, 2, and 3. eThn ePtrnoi X sah psoteipe 1 adn .3 hTen ew acn aceylrl ese eth pilhtraoiesn het AOTNUM of Y daded vrieetla ot X ndubo odwlu TON eb narl.ie tadetS hoetrna awy – ew ened na nyaeniotllexp orem anuotm of Y to LMOELCTYEP nbuind X nad treefoehr htree dwlou tno be a oen to neo niectdopi ni the i laarSmrihpg lcoig ippseal rfo eth nearws hceoic that aestts oi"nrtpe X psxsersee all fo the itepopse depsserex by irtneop Y, utb rionept Y sode otn eserpsx all fo het peiospte dxseepers yb npreiot ..EX. g fI ipeornt Y hsa pteposie 1 nda 2. Adn npoerit X sah popeeits 1, 2, adn .3 eeHr aagn,i ew avhe ifidsseat the awsnre oichesc ioctnon,id dna no aemtrt ohw cmuh ew crianese erinpot ,Y teroipn X lwli slilt veah poeepti 3 ondbu in isht .asce +5
69_nbme_420  Just to iflryac orf het rstif cra:ensio We vaeh 3 eeiptops no Y, dna 2 soeteppi no X. thTa ,emsna unmsisga the itsoppee aer lal etprnes in qleau tn,smauo fi I dda 030 sgram fo portnei Y to eth iultoosn - loyn 020 rmsga lilw bidn nrpeoti .X NDA YNLO 200 agsrm of tniorep X nca eb .bunnuod Hepo teh brmunes e!lhp +1
fruitkebabs  For ndbyoya stlil kctus on rnPeto"i Y srspeesex lla fo eht eeisptop erexpssde yb einrotp ,X ubt reonpti X seod o,n"t utlhhoga hsti mtsetnate may be ue,tr rhtee is ton onugeh tfamnriooni ni hte soueqnti to eovpr i.ths eW wkon ofr catf ahtt baecsue eth Aoutnm fo allebde X nubod esechra 0, at eht vyre ,laets roipetn X dna Y xrpeess het maes ptoeeips sienc ta a taicern ecortnt,ncnoia Y si aebl to lleoeytmcp dlpiecsa lla X fomr eth systme. shTi sd'tnoe ecxudel the sboipstyiil atht etreh yam eb etrax tpipoees on ,Y tub it tn'oesd perov ti ireeh.t +4



 +2  upvote downvote
submitted by amarousis(27)
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so owh oluwd hte prhga olok for tripneo x spsxreese lal fo eht peptosei esrepsedx yb oetinrp ,y tbu tenprio y does tno pxerses lla fo hte eoesiptp dspeeexrs by etrnpoi x?

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drw  hent moes a-nXit otnnac oeecrtla to Y veen Y si daded ta etavwehr gihh eods. ta shti dncnioi,ot teh niel anc neerv uchto eht x.si-aY o n hte a,torycrn fi Y xsepser all eipstoep on hte ,X but X osde otn esxsper lal stepoeip no teh Y, atth samne seom Y eiepstpo era not seen no X. at sthi idnoi,octn I t'ond wnok what lliw eb hte inel lkooed ile.k +1
medbound57  I kitnh ahtt the i'nesl owrawddn oplse ludow eb set,pere esnci Y ash moer sstei ttha het biaoytdn wlodu ibnd t.o +

why this is wrong- prtoein y has all epitopes of x and protein x does not have some epitope



 +1  upvote downvote
submitted by usmleboy(19)
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An iotydanb nca lnyo rneioegcz a lnisge ippt.oee eSicn we see eth erom Y adedd selda to sesl X nduo,b hnte ouy anc aornes etyh ehras the easm iindgbn ,estis adn Y si oienvrroegwp X.

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srmtn  OMG htsi is teh nasreo hy!w aknht oyu!!! +
srmtn  but erhet era noatsebiid ahtt can ertatnci wthi 10 piealmp.xetoe.pes. ..MI.g syror ogt tosl angia (: +
chj7  orF oaneyn tsill ginlewld no hs,it het roespcs hety talk btaou ni teh eiquotns tsem is lbpossyi oalnpcolly s(thu eht esisu of tulpelim epie)os.pt +



 +1  upvote downvote
submitted by rhizopusmucor(1)
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I dunof t,ish I tinhk it siegv kinda fo na niea:axlopnt If hte irosrnegse fo lgo A(/()'A 1-) on -gol B si nielar hwit a elspo fo 1-, tnhe tish ncsaiedti ttah the oamitagnsn is vtempitceio and yb nnideiftio teh ongista and oginnatast cat at eth MEAS ioegriontnc etsis. oS ciaaylbls eht omer uoy add ,Y teh sesl X is ou,ndb hiwch anmse tyeh heav a msae rurltctusa ncponmteo )poiteep( adn tmsu tac on eth eams sit?e Dtno' onwk if itsh mseka .s.e.sne

cgcnutalsagyubp/en~o:1/hp/.riceelb.sjistu/.fhhadodmbhd/itp/smtts

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 +0  upvote downvote
submitted by stepwarrior(29)
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itsh unseoqti wsa eurtt S,B ubt teh way I fidjsiuet e"mas ppietoe"s was htta it dsai "in hte xentcto of mrniteaus- ,X" ei,.. hihwc eppoiste wduol ahev been ddoveplee ni hte exttcon of eth ebidisnaot eets.prn 'tIs illkuney htta Xi-nta isotideabn wlduo dbin to oeieptsp on Y ahtt 'nerta no .X tBu yuo colud ruage eerth are heolcariett epspeito no Y taht dlcou eb dunob yb neroaht dbnayoti atht t'osden xstei in ihst aicenr.os

yVre wrnad tuo dna toko em 5 itmneus to lcyatlua grfeui tou no het t,ste hnsetoly a wteas of mtei ni my ,opniion ubt erhet uoy g.o

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 +0  upvote downvote
submitted by peachespeaches(2)
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cBaeuse it si a strtahig nrdwowad ,loeps uyo nac also tell htta Y dan X era dubon in imlrasi aswy by edobsit.ian hatW teitfsienefdar eth ot,w nte,h tisn' teiepop binnidg a,iibaplcyt tbu eht nntic.creotaon lAl seel lquea ihtw niibgdn its,es orem Y hwit na gnughacinn uaomtn of X wlli alde to esls X d,bnuo in a 1:1 nramn.e

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 +0  upvote downvote
submitted by ilikecheese(46)
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igHh X si ubond whne olw Y is daed,d adn olw X si oubdn hwne Y is oddeaS. d ABEMY ehyt aer otegcpnim ofr eth sema gnidbni eeptposoipt/ due to ihst shaniloteipr eieo=p(pt dnaotybi ndiginb ise)?? ??t??????

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 +0  upvote downvote
submitted by breis(56)
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uoyr usges si as gdoo sa ..e..........................n....i..............m.......................

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nala_ula  I tnsep so ngol on stih iuntoseq nda .em.a.s haaahh +



 +0  upvote downvote
submitted by am.cassandre(0)
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nRa sorcas a soietqnu mrasili to shti in hneaotr inoequst bn.ak nI atth is,uotqen reteh swa no gnecah sa the otnacitcnnreo of teh enw entopir wsa ddead, ihhwc ntmae tath hte wot rpienots idd not eahsr liraism set.eoppi nI tshi sue,ntqoi the ntbiyaod is stju gtynir ot nbid ist epoept,i so ignadd orem or y nsmae slse idbnnig fo preiont x cuaeebs hte natoidyb fvsaor teh nptrosei eth emsa.

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This question tests the basis of competitive inhibition. if they express the same epitope, they will bind the same receptors. Adding more X will mean less binding of Y, hence the downward slope.



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