NBME 22 Adenylyl cyclase (NBME Answers)

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Retired NBME 22 Answers

nbme22/Block 2/Question#22 (reveal difficulty score)
A 35-year-old man comes to the physician ...
Adenylyl cyclase 🔍 / 📺 / 🌳 / 📖
tags: endo repeat

+12 upvote downvote
submitted by ∗osgoodschlatter10(41)

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hTe eetprroc in ueotsnqi is a G pitoern rptcereo no teh tyitupira ms.sa sihT dwluo be the GRHH .prercteo ehT HG roeeprct illw eb repnset aonwermdst os taht HG aeeesrld fmro eth triyuatpi can nibd to it h(etes rae TSKTAJ/A cHeorrRs)GptH.e eotepsrrc rea ¬Gs rto.rpesec Teesh cprroeets ear dounb at eht aniuaubst-phl to GPD ni teh neicivta taset. hWen HGHR bisnd yhte aidtvctea nhwe GPT ctthseaa to het -psiuahubtaln nisatd.e ndA hebryte ootosrepm nayeld alesccy ttiiP.GcyveTaas is rseonelpbsi to elcaev thsi TGP orfm eth hlaap stuubin to hctwsi of eth ee.rcoept foeehrTr a kalc fo eaGsTP ctaytvii wlil enrdre eh sG peorcetr ni a oepdnrolg on ttase  Ieascerdn ityvacit of Andyel sy.elacC

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osler_weber_rendu lBialrtni lentaiapoxn +1

skonys Is it ssle otbau GRHH aginvh a PI3 ernycosda esngmresa ro GH ugnsi /ATTASKJ dna orem htta we rewe supsdope to zneorigec tath sGa si a Gs celudop eceprrto adn Gs ksrow throhgu ydAyelln .alyeCcs PTG bnsdi to Gs dna tmsu eb spseoehtyohdplra by a aesGPT ot eb taacvi.nied esBeacu eth tmuro llsce clak siht ci,onfnut Gs atssy eoorspydtphahl dan edllAyyn aCyselc icosnuetn to eb cvtatdi?ea Im just decnfsou no fi igwnkno the aycsnredo nrsgamese sysmtse vnee ttrema ro if mayerlacgo is ownrht ni sa a adistrcrto rmfo het noiortfamni p.oedidrv +1

weirdmed51 GH no’esdt vhea PI3 ,rsmeenesg ti ahs cAMP +

weirdmed51 HRHG * (osr)ry +

This is really helpful in explaining why the question is NOT asking about growth hormone receptor

+/- qfever(67)

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+8 upvote downvote
submitted by ∗hayayah(1212)

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owhrGt omrheno igaselner eorhonm csat iva Go-lcedpu co.rpsrete G dploecu cepoetsrr eden GTP to oebecm dtetavaic nad PGsTea ot eocmeb vciadtnit.ea

oN se-GTPa -gt&;- cyocirlanlh ctveia rogwht neomrho engaielsr moorneh coerterp -&g-t; nttsanco tiiovancat of nlyladye yaelcsc / MPAc aawyhtp nda laeeers fo grohwt nmooe.hr

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mcl Tish firegu si ufeusl d3..9usdf7f0a5c6d/7trh8ee4/3b70sdgsmaau/0i6.2up-07/12gi041ag1sic1n8e5o5:l2-se-60-2to-baF/82.z1-6neice/mppr4ea23w0f +1

mcl 33.afie.e0651o22-n[-a-14:e]5f0sio02m6/sehi6207/p--1/mz7s7/87b4d.i/kblg94r28i.)a1w/8ft0dudgstr1l3eac(Fg-ec2nc0unau60edsppa5 +

meningitis owH idd oyu nkkwo ti was HGRH adn tno GH er?spe +4

meningitis nrm;deevin I stuj aerd ownd .bolew nhTka uyo +19

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+0 upvote downvote
submitted by goldenwakosu(7)

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Wyh is eht earwns ldeaylny ae?lyscc I oodlke in AF nad I asw taht GH sesu teh A/KJ2TSTA thapywa dna htta -G1FI euss hte AMP aeinsK tyh.aapw tNo rues hwo dnlyleya laeyccs yalps onti s.hti

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pug_sheen I itkhn etyh aer kingtal obatu the HHRG eorcptre on mattprososoh, ihcwh works ohhrgtu eht cAPM hay.atpw +

staygoodpupper I nd’ot onkw hwo ti tarseel ot 1/GFG-IH ni apcuiltra,r btu teh esnoutqi sida ehtre was a tiamtuno in the pahla unutbsi fo G,s whihc svceiaatt leydayln eylcas.c +3

kash1f I rgaee eth ttnipea odes ehav gm,Aoyelacr utb ni hte ntioueqs it lektad bouat owh the tptnaei dha a aomiuttn thta vrdteenep the eTsaPG ctiviyta of aGs. So Gs wuldo be irvveaoect >-- scseex edlylnay ccelysa +31

hyperfukus guh i wsa so tcxdeie oto bc i gthhuot i mbeeremedr akj ttas alpiecfi +3

skonys nseDt'o HGRH tac othrguh an PI3 ascyneor mearnsge?s +

xmen teh rtoum eercsest GH. GH cta via a AATJTSK/ tw. BtuhaayP the HG esirocent is mtseldatui aiv a RHGH otrhugh a sG. hTis sG ni itsh 'srumot elcsl si audtmte dna is yentmeaprln t.cifa os APMc will c.ienrsae +1

weirdmed51 ysonsk@ GHHR kowsr vai AMPc +

kcyanide101 nHGR si P3I --- emrbemeR AGTO A?GH HGHR is MCAP ebmmeerr TAFL APMhC +

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