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NBME 22 Answers

nbme22/Block 2/Question#16

A 60-year-old man is brought to the emergency ...

Prostate adenocarcinoma

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Almost got tricked by this one because osteosarcoma also causes osteoblastic lesion. Osteosarcoma most commonly metastasizes to lungs though.

impostersyndromel1000  This was in pathoma, he said prostate cancer causes osteoblastic lesions and "the board examiners really want you to know that". also following the potential site of mets helps choose the answer +  

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submitted by lisa(0),

Hints. His age + Multilple blastic lesion pointing out at metastasis. Negative protein electrophoresis ruled out Multiple myeloma

drjungly  All primary bone cancer - mc seen in age b/t 20-40 peak at 25. Prostate adenocarcinoma - mc seen age >50 yr old. Source-FA 2018 +