NBME 22 Carboxylation of precursor proteins (NBME Answers)

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Retired NBME 22 Answers

nbme22/Block 3/Question#12 (reveal difficulty score)
An 82-year-old woman has been bedridden since ...
Carboxylation of precursor proteins 🔍 / 📺 / 🌳 / 📖
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submitted by ∗humble_station(85)

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Wirraanf tiiihbsn Vti K edtnednep hysstiens of sfatocr &;apm nr.iseopt

Vit K si eeyncrsas rfo het anuoaimtrt of iltntcgo orstfac II, V,II ,XI X nad protnei C p;ma& S

So a udrg ahtt cna ihbinti eth otaaylrncxiob fo errrcpous ispernto or in reoth osrwd inthbii het uatotrnima fo het tcgiltno sfratoc liwl eaceresd eth isrk fo hromsistbo in stih taiep.tn

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Extra note: Thrombomodulin alpha (a recombinant drug) can increase thrombin degradation and Protein C activation, hence can also be used for anticoagulation. (But this question asked about decrease in which of the following)

+3/- apurva(101)

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submitted by ∗haliburton(224)

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infraraw tnibhiis eth sieysnsht fo asfrotc ,II ,VII XI, X, C, dna S by lbcgnkio teciorudn of idoizxde nvimati .K heT nzyeme exodEip tueRcsdea is idetnhiib by a.frnrwia eTh udederc evi(t)ca mrfo fo tiv. K si a atrccofo orf aga-mymmlualgt rol.axbcaesy

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link981 oS rsafotc II, IV,I IX, nda X era srreupocr iponer?st GOTF +2

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submitted by ∗humble_station(85)

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Wraairnf sihtinib tiV K pentdeend ytsnsseih fo stfcrao &pa;m ertnpsoi.

itV K si nersyscae for het nittauroma fo giltntco tcfaosr I,I VII, IX, X and nptorei C ap;m& S

So a grdu hatt anc hnbiiit eht xitnoolcrayab of rsrocrupe pornsite or ni thero rswod tbinihi hte taanomrtui of eht lctgonit aoscrft illw eerdcase teh rski fo tmibhoosrs ni ihst epan.tit

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ajss ihts si hwy narwfari is gevin sa hapsplyoxir erfta itsh pety of usrregesi +

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submitted by ∗sup(31)

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yWh nto 2IGP yb ywa fo AS?A iypcaEsell gvien etroh wnsrea hoiscec of ntispreo C + S: es'ndot rfnaiwar aols pussepsr e?hest

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imnotarobotbut oerintP C adn S rea TticmIothoAbNr-, so haglothu nfrraWai sode cadreese ,thme ythe nwulo'dt acseedre eth 'attpiesn kirs for osthomisbr +1

epr94 eht osenituq ask rpesosupisn"" of wchih neo will rdaecsee ikrs of stmsoroihb i f oyu psruseps C dna S chhiw nda aont-irbctmioht uoy etg itbrcomtho +3

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