NBME 22 Carboxylation of precursor proteins (NBME Answers)

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Retired NBME 22 Answers

nbme22/Block 3/Question#12 (reveal difficulty score)
An 82-year-old woman has been bedridden since ...
Carboxylation of precursor proteins 🔍 / 📺 / 🌳 / 📖
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+6 upvote downvote
submitted by ∗humble_station(85)

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iWrfaarn ihsibnit Vit K eddnetnep itsyenhss of ofsactr p;am& isnoet.rp

Vti K si caneesrys rof eht ttmunaaoir fo itolngct satfocr I,I IIV, ,IX X dna petoirn C &;map S

So a gdru taht nac hntiiib the obirncaxtaylo of opeucrsrr tsrpineo or ni rteoh rsdow binihti teh ttomuarain of eht tngotilc torfasc will edeacers the krsi fo bmiroossht ni tish tepanti.

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Extra note: Thrombomodulin alpha (a recombinant drug) can increase thrombin degradation and Protein C activation, hence can also be used for anticoagulation. (But this question asked about decrease in which of the following)

+3/- apurva(101)

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+2 upvote downvote
submitted by ∗haliburton(224)

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arafinwr intisibh the sntsseyih fo rstoafc I,I VII, ,IX X, C, dan S yb gcnokbil rieuncotd of ioidxdze mavniti K. heT mzeyen pixeoEd cRtesadue si iinebidht yb waiarnrf. ehT reedcdu i(tva)ec mfro of it.v K si a actrcofo ofr tauylgaamgmml- sbaalery.cxo

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link981 So tsracof II, ,VII ,XI nda X are uporrsrce sit?pneor OGTF +2

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+0 upvote downvote
submitted by ∗humble_station(85)

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Wnarrifa bstniihi itV K deneetpnd ssysntehi of oasftrc pm;a& .pretnsoi

itV K is scsyearen rof eth otaatrmuni of tctloing crasfto II, I,VI XI, X and rtoenpi C mp;&a S

oS a dgru tath can biiinth hte xtcoblnoairay fo cerouprsr rpsnotie ro ni ehort rsdwo ntbhiii hte irtomtauna of eht gttclino raofcst liwl rsacdeee het irsk of rsthsmoboi ni hist pta.nite

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ajss this is wyh awrfarin si niegv sa alhyxrospip tefra thsi ytep fo srgeriseu +

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-2 upvote downvote
submitted by ∗sup(31)

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hWy nto IPG2 by yaw fo AS?A ecaEllsyip ievng teroh eanwsr csohice of ortpesni C + :S dnt'eso iarwranf aslo ssupesrp s?hete

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imnotarobotbut toPiern C nad S rae tTmhNAo-ribIot,c os taglouhh arnraifW osde crdaeese ,ethm thye 'duwnolt eeadsrce hte 'ntatpeis kirs rof otssiohrbm +1

epr94 eht esquntoi ksa snrie"u"sospp fo wichh one wlil aseedcer kris of omtsorhsib if yuo ssppeurs C dna S hchiw and oati-thimtcbrno oyu get tcoriomhtb +3

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