NBME 22 Carboxylation of precursor proteins (NBME Answers)

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Retired NBME 22 Answers

nbme22/Block 3/Question#12 (reveal difficulty score)
An 82-year-old woman has been bedridden since ...
Carboxylation of precursor proteins 🔍 / 📺 / 🌳 / 📖
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+6 upvote downvote
submitted by ∗humble_station(85)

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rnifarWa inthibsi tiV K eetnndped stehyinss of tsrfaoc m;&pa rtesnp.oi

Vit K si arscsnyee rof het aonuamttri of nogctlti catfros ,II VII, ,IX X dna pnrioet C ↦ S

So a rgud atth nca nithiib het yoaotinlxbrac of rosrrecpu ipenosrt ro ni ehtor osdwr binihit hte onraatuimt of eth icltogtn corfast will ecdesrae eth rsik of ssmrbthioo in stih .itepatn

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Extra note: Thrombomodulin alpha (a recombinant drug) can increase thrombin degradation and Protein C activation, hence can also be used for anticoagulation. (But this question asked about decrease in which of the following)

+3/- apurva(101)

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+2 upvote downvote
submitted by ∗haliburton(224)

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afnrwrai insbthii the tinsssyeh fo cforsat ,II VI,I ,XI X, C, adn S by kglcbino certnudio of oieixzdd vanmiti K. heT zneyem Eopiedx edtaseRuc is hniiteibd yb faiwrran. heT dduecre ei(vatc) fmor of tiv. K is a otcrocfa ofr gga-mlylmatuam .asleoxbracy

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link981 oS toscraf II, VI,I XI, nad X aer rrueprsco n?espirot TOGF +2

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+0 upvote downvote
submitted by ∗humble_station(85)

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Wafnrair stbiniih tVi K eneedpndt stshsynie of cratfso ma&p; opint.rse

Vit K si rnsyecase for eth unarmitaot of ltitogcn oscatrf II, I,IV XI, X nad pitnreo C mpa;& S

So a udgr thta acn ihiitnb eth oanbcrotiayxl fo rrcourpse spineort or in hrtoe swdro iihtibn eth trioanmuat fo the lntgctio rsoatfc lwil eradesec hte rkis fo stishroobm in isht na.ttipe

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ajss tish is hwy nrfiarwa is nivge as ixsyophalrp ertaf tsih tyep of rssiuegre +

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submitted by ∗sup(31)

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Why ton GI2P by ayw of AAS? iEsleplyca vnegi ohetr reawsn ohccise of oernpits C + S: 'nedsot firraawn aols sssreppu tee?sh

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imnotarobotbut Ptrnioe C nda S rea IhotAmNt,irT-cob os hlugthao iaWfrarn esod deesearc h,etm ythe loudtn'w saceerde het tptsne'ai ksir ofr mroiotsbhs +1

epr94 eht iotsuneq ask rssinou""epsp of which noe iwll saeceedr ikrs fo bssrmtihoo if ouy uespsrps C dna S ihhwc and ohni-taticbormt ouy egt bitthmcroo +3

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