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Retired NBME 22 Answers

nbme22/Block 4/Question#13 (reveal difficulty score)
A 36-year-old woman comes to the physician ...
Cytosol with translocation into the nucleus ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
tags: pharm repeat

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submitted by โˆ—ilikecheese(46)
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corticosteroids - steroid bind to receptor located in nucleus or cytoplasm --> transformation of receptor to expose DNA-binding protein etc pg 332 FA 2019

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weirdmed51  Anyone knows the answers to other options ? +1
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  • Steroid hormones commonly bind to intracellular receptors.

  • Most steroid hormones bind the receptor in the cytosol after which it moves to the nucleus word acts as a transcription factor at the level of the DNA.

  • 0ther similar hormones, like thyroid hormone, estrogen hormones, etc, find their receptor in the nucleus at which time it binds the DNA to exert its effects.



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