NBME 22 Carboxylation of precursor proteins (NBME Answers)

Retired NBME 22 Answers

nbme22/Block 3/Question#12 (reveal difficulty score)
An 82-year-old woman has been bedridden since ...
Carboxylation of precursor proteins 🔍 / 📺 / 🌳 / 📖
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+6 upvote downvote
submitted by ∗humble_station(85)

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ranirWaf niihstib tVi K ndedteepn hstysnsie fo oaftrsc &;pam psoe.tirn

iVt K si snaceeysr fro teh moauntitar of ctitglno srtfaoc ,II ,IVI XI, X and ipnteor C m;&pa S

So a drgu htat acn nhtiibi eht ooxriaybtacnl fo eucoprsrr peiosrtn ro ni roeth dsrwo hinibit eht attrmouain fo hte itntgolc tfcasor wlil reeaecsd eht iskr fo rsimsohotb ni this .patetni

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Extra note: Thrombomodulin alpha (a recombinant drug) can increase thrombin degradation and Protein C activation, hence can also be used for anticoagulation. (But this question asked about decrease in which of the following)

+3/- apurva(101)

+2 upvote downvote
submitted by ∗haliburton(224)

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wriarnaf hsiibtni the sitnsehys of aotcfrs I,I I,IV ,XI ,X C, dan S yb giblkcno cedirontu of didixeoz anivtmi K. heT yzeemn oepxdiE auRtdcese si dniiehbit by win.frara ehT rceedud vai)e(ct rfom fo v.ti K si a tarococf for amty-lluggamma c.raelbysxao

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link981 So atsfroc I,I ,IVI X,I nda X rea rsucorrep neirtp?so FOTG +2

+0 upvote downvote
submitted by ∗humble_station(85)

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nWaairfr hnibiist itV K ndnpeeted setsyhsin fo rafsoct p;ma& oes.ipntr

tVi K is aesecnsry rfo the ruittanmoa of cgintolt tcarsfo ,II IVI, ,IX X nda nrieopt C m≈ S

oS a rdgu tath cna itihbin teh iaxacntoyrblo fo uerrorcsp reinpsot ro in orthe dwros ibhiitn teh otuaamtirn fo eth ncgoitlt tcasrfo lilw eecerads eht risk of mrbsihotos in this a.pttine

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ajss htsi si ywh narwrifa is nigev sa raoypplxhsi ftaer sthi ytpe fo riesresgu +

-2 upvote downvote
submitted by ∗sup(31)

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yWh not IG2P by awy fo A?AS pecillsaEy egnvi htreo ransew scoecih of etrinops C + S: 'oentsd rirfaanw osla sssppure e?tehs

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imnotarobotbut irtnPoe C dna S era hNoiA,tIrto-cTmb os aolhthgu rfWarain edso ceedesar them, tyhe 'wnlodut eseecadr the apei'ntts irsk ofr osbitmorsh +1

epr94 the qtuiosen aks "sseroipuspn" of hhciw eno wlil eeecdars rski of irsmobthso fi you sspsepur C and S hichw nda cboanomti-hritt you etg oihobtmtrc +3

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