to snoo-finity ... and beyond!
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Misoprostol is indicated for prevention of NSAID-induced peptic ulcers (FA 2019 pg 393). Omeprazole is better for treatment
so just to clarify - it's the "symptom-free for 3 months" that rules out thrombosis?
It's moreso that at rest there's no changes, but during exercise there is. Like the pathophys of stable angina.
I think it's more because of the 2-month history of PROGRESSIVE angina sx with exertion. This points to a chronic process rather than an acute event.
Meckel diverticulum itself occurs in 2% of the population.
Also it would present much sooner rather than in a 28 year old man.
Meckels is an incidental finding in 98% patients. (only 2% symptomatic)
It is a well known lead point for intussusception
I think you made one slight mistake.
TIBC = total iron binding capacity. It is synonymous with "transferrin saturation". This patient has increased transferrin saturation aka increased TIBC.
The transferrin molecules are saturated -- it is incorrect to say "as transferrin saturation increases, there is less circulating carrier molecules."
It is more correct to say that the amount of free (unbound) transferrin is decreased.
@hello Transferrin saturation and TIBC are not synonymous. Transferrin is calculated using total body iron / TIBC.
While the serum iron level continues to increase, the transferrin level decreases. Thus, the amount of transferrin available to bind iron (TIBC) decreases and the amount of transferrin saturated with iron (i.e., percent transferrin saturation) increases.
I got this correct solely based on the patients demographic. Glue is cheap and easily accessible to underage populations.
Kinda racist of us but that’s how I reasoned my answer too lol @sbryant6
how is it racist if the only thing thats given is his age lol @whossayin
Im pretty sure so is strept pneumoniae
COPD is also exacerbated by Viral infection: Rhinovirus, influenza, parainfluenza; and Bacterial infection: Haemophilus influenzae, Moraxella catarrhalis, Streptococcus.
however, the questions gives a hint that it may be legionella = "weekend retreat" which may be associated with this infection
From FA 2017 pg 139: Legionnaires’ disease—severe pneumonia (often unilateral and lobar A ), fever, GI and CNS symptoms. Common in smokers and in **chronic lung disease.**
I also believe that the other attendees showed signs of pontiac fever, which is another hint they tried to get at.
i did it wrong and chose influenza virus since it is most common infection in COPD but the clue in the Question is that the other attendee didnt get sick since in legionella there is no person to person transmission
but in Uworld s. pneumo is one of the most common bacterial exacerbation of COPD legionella wasn't even mentioned. How do we rule out s. pneumo ?
maybe because in children s.pneumo causes otitis media?
Another hint made in the Q stem is the location being rural Pennsylvania.... Legionnaires disease was first discovered by the outbreak in 1976 at a convention held in Philadelphia, Pennsylvania. Not sure why I know this fact...
Biggest hint towards legionella to me was that they all were at a residence hall... i.e. where there'd be air conditioners and such.
Why not 'give foods according to normal caloric requirement'?
@cry2mucheveryday because feeding to the caloric may be too much or too little for this baby. considering the baby's crying only resolves with food, if you've already reached the limit, are you just not going to feed the baby? that's how i thought of it. "maintain comfort" is the key phrase.
Why is it regurg instead of stenosis?
Vague question requires a lot clinical reasoning.
mitral regurgitation: holosystolic murmur( this cv: midsystolic), enlarged LA, LV
Mitral stenosis: diastolic murmur, enlarged LA, normal LV.
only best explanation I can think of: early stage Mitral regur, that's why the murmur is not holosystolic but midsystolic and LV still adequately handle the situation
@hpsbwz it's regurgitation because the murmur is SYSTOLIC, when the mitral valve is not supposed to make any sound. mitral valve leaks in systole, which causes blood to back up, which causes the left atrium to work harder and eventually hypertrophy.
Mitral stenosis would be a DIASTOLIC sound, which is when the left atrium normally contracts.
Memory T cells live for six months or less in healthy humans (Westera et al., 2013), whereas naive T cells can live for up to nine years
so the bone marrow does not take the role of the thymus?
@sweetmed, does that mean that if someone loses their thymus, they would develop imunodeficiencies appx 9 years later as the naive T cells have died off?
@dr_jan_itor no, because once all of the thymocytes become T-lymphocytes, they are stored in lymphoid organs until they're needed. this is why removal of the thymus in MG does not cause any immune system deficiency.