Stent thrombosis vs re-stenosis. Stent thrombosis is an acute occlusion of a coronary artery stent, which often results in acute coronary syndrome. Can be prevented by dual antiplatelet therapy or drug-eluting stents. Re-stenosis is the gradual narrowing of the stent lumen due to neointimal proliferation, resulting in anginal symptoms.
Stent Restenosis occurs from scar tissue grows over stent causing “neointimal hyperplasia” and narrowing, ischemia symptoms return Tx: prevent by using drig eluting stents eg. Sirolimus. Thrombosis Post stenosis is Acute, stent serves as nidus for thrombus formation usually 2/2 missing mediation. Tx: prevent by using dual antiplatelet treatment [aspirin+clopidogrel/ticagrelor]. After 1 year, endothelization of stent occurs and there is a lower risk of thrombus, Tx lowered to just aspirin.