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Retired NBME 23 Answers

nbme23/Block 2/Question#32 (reveal difficulty score)
A 2-year-old girl is brought to the physician ...
N-methyl-d-aspartate (NMDA) 🔍 / 📺 / 🌳 / 📖
tags: pharm neuro repeat

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 +19  upvote downvote
submitted by nwinkelmann(366)
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oS, rof smeo osrnae, mnurnoreteatrsist is soenitghm 'vIe LAWAYS gerudtslg w.ti.h. abbplyro bucesae I ast'nw uthtga it wlel so vnere yeallr deelnar ,it sujt eenlrad ungoeh for werevath xea.m I just udfno sith obo tohughr NBIC dna its TF!IATNCAS ts'I omfr 0012 os gthmi eb do,l utb ti aws ea.rtg Yuo cna areshc hhugrto hte ookb dan ifdn eht shctrpea. I typetr much tsuj twne torughh all of the nrnmrsuettiaetor et.arhpc nB/os.0/htt/m.oingh/7i.bsvp/ww1.NkKcbwol:9n9

yM nmai tst eeyaa:-ukaatlamGw = jraom exrtocytia tnneturi.sorermat woT tsype of oc strp)e1:er mrptteacb,oio ostm fo hiwhc are eyppatcrins iG ichhw edsla ot ceeseadrd DMAN eecroprt ytvitiac nda rksi of iott,iectoixxicy or ossynpitctap qG ercetsrpo ahtt elad to ciesrean a,N+ +,K and asdeecred tamtlauge ssueac aroeilzonipdta nad isnecdear +gM+ taecipdlmesn dan DANM rreepotc ivicytta and rski of iyett,oxticioxc nda 2 ) onotipiroc ahseclnn lniicugdn MADN adn eata/nAAMiPk lnnah,ecs iwhhc all alowl cfnposincei naotic uilfnx, tbu ylon ANDM alsowl ++Ca fuilnx dan( nlyo ni a aovetgl tdednpene nenarm faret fefsuicnit naloitdiprzeao sah siplcdaed teh nrihtibio +gM+ oin ni eht n.c)nahel

AGBA and gnyecli = thiinioryb nnsmearosr.iurtett 1) -BAGAA nad GAB-CA = cipiroonot lnneasch ttha lead ot lxfeu fo ,-Cl nad idtsepe stih auisngc pnoedaiitalz,or teh eounrn tllis tssay owlbe gsterni ottlp.aeni -BAAGA iibndgn tise rfo bb,siturtaear ssti,edor B,GAA nda pnixrotico = insied oper fo hlaecnn. BAGAA- niibgnd iest of nzeapnesioedbiz = idsoute of rope fo h.lncnae )2 cynGeil ealnnhc is a ryev ilsaimr Cl- xeulf elnanc.h 3) -AGABB is a oeicbrtptamo cnlanhe ttha ievttcsaa Gi aigdenl to ddcsereae AMcP hchiw vtaieacst uelffx +K neanshlc nad intishib a+C+ ulxnfi nlhansec ilagned ot hzraoiapi.tolryenp

gocieBin niames = cneceitsamahlo mdopniae oadi(oitcornn of dbyo vtoemen,m raewr,d oin,itavtom rnoniet,)feecrm pnoinhreepnire (l,seep ,feskeawlusn tnenta,iot gindeef ih,earbvo pnepinihere le(swot occoiartnnten in ,CNS) pslu toionnres se(ple, nskslaeufe,w oidse,rnesp axytie,n aenasu) nda hismtinea ls(uara,o aot,netitn alr,lgey suiset adga,me nda yma lienfncue bodlo irabn wl.)of Osoyblu,iv lla fo sthi is in atiioddn ot drniegeacr satounormisnserni nad ti,gfhl ,fhgtri nda hgfit sorespen.

TAP and hrteo suniepr = xrtiecotay rassimno,ints c-desaeeorl twih ertoh loulesmamcell- msrrnsaetriueo.ntt nsdioneeA in'st aliyclsalcs ercnseiddo a namrtrtoensuetir aseeubc ti ns'it etsoresaedelrd/ in ++aC etnepdden mnren,a tbu didvree fmor ATP bforee hgianv na ocyxarteti pontale.it

ceehlinAltoyc = maojr etteiontasmrunrr onivlevd in ernunotsirosmains avi cimrnuas dan cotcninii esreo.rcpt

Pdepite tesrutnrroenaitsm = mmnylooc lsaderee as ippeedptor gralre urpsreocsr atth rea veeacdl yb ccseiipf zsenemy taht rwee in the esam aretonsumnreittr lseevci npuo ee.lsrae eiFv yespt = agubt/inr idpestp,e oiiopd deei,tspp ryupitita t,espdip omchtailapyh gisneelar noomr,esh and stheo ont ssicld.feai mseaElxp = uorcesrrp ahtt sgive rsei to csanbutes P mhpsupapc,oi( or,exoecnt nad GTI nad eeslraed from lsmla eraidemt NSP C esfibr htta ittarnms apni dan epmeutreatr fnntiioarmo, lropuwfe shionvyete,p bhinteiid yb poiodi pse)pid,te enriknuoni ,A eenroetiudpp K, dan pdneretipuoe a,gamm adn odoiip espdptie gnndicilu npatl lkoidsala il(ek noemhipr), yiechtsnt opoidi eiiat,evrsdv adn droinhp,nse ydnohinpsr, dan hepe.ianlksn nI lrngaee pdoioi eestpipd aer etpsansdsre (e.i. eniaalgsa ),micnsahem ilvovden in opxmcle rbishoeva ueal(sx rttanacoi,t gmisssb/geesaisivvreu h),ivboresa adn lidpcieamt hghto(u nto eiiv)dntfei in iyscpitcrah os.rreisdd

alvO,erl asutrrnrsmtnotiee = pyet esy:tp elmcsolllam-ue etamssttrinr dan seiputnreep,do wehre lal-emllecumsso nirstttmares rea tsfera adn iameted iaprd tpycsani rnosnmitasis .i.e( ronednag SSN ghtggfifiit/lf/hrth ukiqc sseo,n)per erhwe sa euntporespeid nlga(o htwi ibgoiolc aeimsn dna omes lalms clouelme esmsittar)ntr era selrow nad eietdam udrg,ala ploerndgo timns.esrinsanorou

eomS u:pcirset mat.lc_wassonkopure/.uvs/i/nhohdumwt/:rb_epeiirm/p.edrdtnftekt_raehteviwentopu, eAo13:ap/42r9ou/6tnpcs1swpiicf8/aa-c1uB.3intrl-Gwrg/la/dr1g--50gehe80gsaBcf24sre1lAt2eaegTp/uhm6re6berf-sanPtfesebe/wr763a.r-3dop-b0tddiRi-b0o04iht, and rhd/b-b..xd-w-atU/8ln0i=bsolcrux2b=hbea2apee.-wn-_5fhf4ana:1pgg0&d3663s/i/aeiw/eldlg1tr;-wa-e7feit9#1atg1std5e-e/fmg

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sweetmed  This is a.znmgia kathn you +
sweetmed  sTih is mai.agnz nhkta uoy +
paulkarr  ..ahoW. +
brotherimodu  trohS eidov oeenmso otsdep rfom N2-1EMB :swnreas bu.a.ocuyHwp/Dt2hcmus:hQtotww/-?vz4ewwot/=v +6
dorischang  Dt'ndi ifsnih ienrdag isht, utb it kloos eemwsao +3
kcyanide101  If yuo aannw rtiew a tetx boko tjsu yas ..o..lols :) +

  • effect of glutamate antagonist on pt with acute cerebral infarction = targets NMDA receptor

  • decreases calcium entry into neurons = decreased excitotoxicity = promotes recovery from acute cerebral infarction.


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 +19  upvote downvote
submitted by sympathetikey(1600)
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uhTgo qnueiso.t

clReal htta aeeMtmnni eilz(amrh'se dr)gu si a DMAN pReotcer nontgtisAa atth phsel etvnper otciextxiycot yb onkligBc a+C2 ytnre. Tsat'h how I erebmemr sth.i

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veryhungrycaterpillar  tso.n/1/rinc/9jstwht0r:soo0who..wt3rce9//egun/tpe rGat tltlei rdae, dan isth si het apepr ythe tpeytr hcmu baesd hits seuqiotn o.n +
veryhungrycaterpillar  dLenik het rgwon rape.p ntMea ot inkl ihst :neo Mt../7whmw0r/cw/vlh/ib8o/.e6l/s6ni.Patp5mtnscC2gnpc:i +

a picture for better understanding https://2e.mindsmachine.com/asf04.02.html

^ link is dead :( (they published a 3/e) but here is the re-route to the new site if anyone wants to dig in https://learninglink.oup.com/access/watson3e-student-resources

+/- drdoom(1206)

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 +4  upvote downvote
submitted by spow(50)
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  • )A -GAAAB reeopcrst etl -lC in
  • B) lcneyGi si edus ni eht naipsl cdro as an byhiioinrt ua;enrtrrtieotmns osla eslt C-l ni
  • C dan E) Mrtcioeobpat tlutamaeg crteeopsr ear eiprtnG-o cluedop
  • eer,erohTf the lyno gnhit ttah oucld elt C2a+ ni is MDNA rtsepcroe
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thotcandy  oaidngcrc to hsit, H53T si an ino ncnehal mniayl( Na nda K, tub smeo C)a os ttah aws dkain fyef moi +


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 +3  upvote downvote
submitted by lfsuarez(160)
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AMDN opcsrrete ni tshi asce rea begin sued rof gnol etrm ttnaoteipino ihtwin teh bianr adn tuo of lla fo ereht choesic olyn hsti crroepet essu a+C

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 +1  upvote downvote
submitted by chasingdreams101(4)
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I kdipce DAMN esacueb s’it rtoytia,umsl tub si eerht yan eeerpd esrona rof hs?it

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tea-cats-biscuits  Teh Q si yacaultl knsagi whcih fo eth ceepotrrs ues C+a n,ios dna of eth ihseocc ivegn loyn NAMD potecrers do so. +32


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 +1  upvote downvote
submitted by adong(144)
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ouY cna rswnea by srcpsoe of noaiti.imeln Cvtpemit"oie nt"ntioacseir smaek oyu nithk timasltruoy NT. sCsor otu BAAG nad ncyeig.l In eht ortcxe so agat.eltmu paitcboMoret odlwu aemn hers'te enscod esseemgsnr ndviolve dna het rrepoect dowlu nto nasrtitm mcc.ailu cnHee NDMA.

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 +1  upvote downvote
submitted by an1(114)
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usde in logn emrt ntpnoiietoat gglae(un,a )myomer, yMa losa aylp a elor in ngee oicantpsrrint in unnrose

)1 DNMA is a atGmuatle ecpreort sp)b2tye u PAMA is a tbesuyp fo NDMA htat si tyiliilan iavacdtet yb eugtamlta 3 )eerasle NMAD eoprstcre rae dunof earn PAMA etscreorp ubt are tno adevtitac by wlo slvlee fo maltuagte aeleesr ude to a gM oin obgickn‘l’ het c)nena lh4 eFtrequn tcnioA naittelpo ;t—&g utiatonlims fo APMA g&t—; eldaripszeo tpos apnsicty ounenr t—;g& oatvgle neetenddp Mg cklbo of MNDA tereorpc edrvmeo 5) nilufx fo Ca torhhug MDNA ;—> usceas eevn eorm MAAP eestorrpc ot be edintrse tino the mnrebeam (NOT:E PAMA is esoernpvis to Ca dan l)6tamg)taeu ceBesua etehr aer orme roetcsepr to edsnopr to t,i the clel si oerm vepsiosenr to eulgatmta

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 +0  upvote downvote
submitted by zpatel(36)
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lla eht rhseot a epotvientnimco cesin etyh ahev feyiiipfpciccseis(ct dg,asn)il MDAN si eth nlyo ochteeeennlec(nivs pteeviotmci ec,)rproet ash a ngliad iset and ca , na nda .g.e.cnemh iemivptoetc

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hello  eht unosiqte assy vtpociteemi t,oiairtnnsec i knhit hsti si reeifftnd form eietvitpmco .ngiidbn +


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