oS, orf meos eaonsr, unreetoasrttnsirm si eomhgsnti 'evI WLASAY gdtgurles tw..h.i robbyalp usecbae I ntsa'w uttgah ti ewll os nvere lelayr nedlear ,it sujt raledne guoneh rfo retvwahe ea.xm I juts ndfou stih oob ohturhg NICB adn tis A!TSFNACIT sI't frmo 2100 so gihmt be ol,d ubt ti asw .ratge uoY nca schare hroghut teh ookb adn fdin hte prshatc.e I rptyte cmhu sutj wten ghhrotu lal fo eht arntrtsnomruetie tacherp. gto0c/./visb7tln...o:kww/npBhsKw9ob/hm19Ni/n

yM mnai swa:Gttukalaemaae-yt = ajorm cxyoreitat eneo.rtrrttaunmsi Two sepyt of teo:rr) psc1e mto,croabptei stom of which era taepcrnisyp Gi hwcih salde ot rdeesdeca ANMD coreertp ctiiavyt dan iksr of tytcx,xeiiiiooct ro npsosaitcytp qG oercrepts atht edla ot asnecire Na,+ ,+K nda srddaeeec tmtgaueal uscaes poditnaielzaro nda eraeidcns +M+g lmtpnidascee dan NDAM rerpceot iyvtacit dan ksir of x,eccoiitxiytot and 2) oornioptci lceshnna inidulcng NMAD and MAatkniA/Pea nescnha,l cihwh lal ollwa ficsoncinpe tnioca ixnlf,u utb nlyo DNAM llsaow +aC+ lxunfi dn(a yoln ni a oetalgv tnndpeede raemnn raetf tncuiisffe apleztinoiodra has iddapsecl teh htriiniob +Mg+ oni in hte alchenn.)

ABGA adn ygnicle = tiryobinhi srrirtontsnaeetm.u )1 BGA-AA adn GAAC-B = irnoicopto lnnhaces ttah lade to eulxf fo -l,C nda dsietpe thsi uasgcin nalidteopoiarz, hte onnrue tslli atyss lebwo nsegirt etopnti.la -BAAAG inbding esit ofr urbaseria,btt orss,deti A,GAB nda tpoorxiicn = disein reop fo hne.ncla -AAGAB dniibng tsei fo psnzizabdeoeeni = uidtsoe fo proe fo hn.lanec )2 nyGceil encnhal si a very iasmlri C-l xuefl el.acnhn 3) GABAB- is a tcaoirmpeotb annlche taht taivetsac Gi aidlgen to erscdaede PMAc ihwhc cvstietaa ufefxl +K cnhaesln dan ithsbini ++aC ulxnfi scnlaneh legaind ot zepaaoolrnh.typiri

ocBinieg iesamn = hcameoltiencsa mpendaio artino(dniooc of dyob nomev,met erar,wd vimno,titoa tnfecire)ner,mo ennpihniroreep plese(, as,eukewflns ntinoteta, gfinede ,baeiorvh nirneepiehp lowts(e taoncnncoteir ni NS),C spul ensitnoro p,lee(s flknauewss,e ,sespindero ,yanxeit un)seaa nad msienitah osa,ral(u ,aetntitno ,yrlgael eutsis amedga, nda may enlceunfi oldob rainb )fo.lw yliosbuOv, lal fo shti si ni idaditon to cerenridga ionrstaisurnmsneo nad litg,hf rh,itgf nda hgfti poessen.r

ATP dan rheto pisernu = craoytexit osar,itinssmn eed-oerlsca wiht etroh loselecm-amull .ttreenosurrsantim ninesodAe t'sin ylassiallcc odeecsridn a tmsrroerunantite ecsaebu ti st'in /rtseeddoslaree ni Ca++ etdeepnnd ,emnanr but eeirvdd form ATP froeeb ihgvna an cayextorit t.patiloen

eilthAnclcyeo = jorma eurtsannrtmrieot onedvivl in esnrmsonaiuiornst iva ircnsuma adn oincticin trreeoc.ps

detepiP ttuesesoritnnrrma = mocylnmo eareelds as pirpdeeotp gelrra ursopcesrr htat ear ldveeca by efspciic ysnmzee htat rwee ni hte seam iatterrenronumts vlciese pnou lea.rsee veFi yetsp = gti/uabrn epd,tipse diopio peted,psi ritpyaitu es,dppti hhtyaplmoaci enleargis s,rmoohen and otehs nto dsces.lafii pxlaesmE = rsureproc ttha svgei ersi to esctuasbn P ciua,(hmpospp c,orontxee nda GIT and dlereeas mrof slalm riatmede PNS C erfsib htat isatrtnm npai and etrmpueerat ofinn,rtiamo relpwfou tosie,yevphn tbiiedihn by pdiooi tsei)e,ppd ninerkunoi A, dtupneeipeor ,K nda idptenrpeeuo m,agma dna ipdooi sedtpiep ilunidcng antpl iollskaad kli(e erm)npohi, hcttinyes diopoi vdeai,seitvr and deinrhnspo, sypn,dronih nad .nkeaihpsenl nI arelgen opdiio etepdisp rea needasrpsst ie.(. genasalia ,hmn)emcsai vdloenvi in epoclxm ishraeovb esaulx( ,ottacrnati issvsriaeveisb/egugsm ovaibr,e)sh nad imtdealcpi hhot(gu nto diev)initfe in pschyiitrac oi.redsdrs

lOl,vaer eanmruserrittston = ypet et:yps lma-umlllseeco rsasntmttrei and pup,enerieotds hweer llmuesol-eclsam tristsnmreta era seafrt adn itaedme piadr satcnipy isatirsnnmso ..(ie nganeord SNS ifgfltg/igh/frtihht icuqk ersnp)oe,s ehewr sa peuentdesopir la(ong hwit glcbiooi esimna nad osme mllsa emollecu )iarmetrnstst rae rwlose nad eamdtei dg,arlau lepordogn rae.tmnuoisisrnnso

omeS :eupsrcit .ardte.kcah:_o/wmeofodrtnerunteaw/re//ehs_pm.uuipe/rhuvptbtv_dopsiltkneiitmsnw, oteotcg08iofs/ebaad-5AAec66Tnr2rrp0rdtu:th1sue40r6/ecg--ea6nuod0R3r0rBmipb-/rasfeP2-9ap/ai-l1/131wBadi-ili4sptfwbsh3e-eg/wh3rf7pbe/.G1segn2.g4lca8t, and fs/baggxc6tbed9/m0n2;tUen3:ehbprte--plta-.1tdn1e/85f4g#.2ww50gibse-ddlgialh16wbehr=-la=awef3e1ir/-iu/-.&7_fs/a-daxao

gohuT es.uioqnt

Relalc atth taemnMien (rmielze'sah r)udg is a NMAD cRopetre tsgoninatA atht pshel etvrpen eiocxtcytitxo yb giocBlnk 2aC+ tnyre. T'hast woh I rmbreeme .tsih

• A) BAAG-A serrtpoec etl l-C in
• B) liGycne is edus ni teh apnsil cord sa an yihbriiotn sonatertetmrrn;iu slao slet l-C in
• C nda E) pottacobeMir tguametla ceoetsprr rea -inoGpert opculed
• ,hTrforeee the noly hingt that oucdl tel aC2+ ni si DNAM rcepotesr

DMAN epsrcerot in hits acse era ngbie ueds rof nlgo emtr onotpeinatti iwtihn het nibra nda tuo fo all of ereht hicseco lyno ihst rptceroe suse C+a

You anc rawens yb ecrossp fo ii.eonltniam etiimoe"ptCv tae"iconstrni maske you ktihn msyatoltrui TN. Cssro otu AAGB adn .licnyeg nI the cxrote so u.gttaamle rocoeptMiatb uwlod nema sehetr' cosedn sreemsengs levndvio nad teh ecprtero wluod otn asinrttm ilacm.uc eHenc DMNA.

sude ni gnlo emtr painitteotno gnuga,e(al rmy),emo aMy laos lpya a orle ni eegn iorpnsrtantic ni usrenon

)1 DMAN si a mlttauGea optecerr )p2 bueyts APAM is a byeupts of DNMA ahtt is tnliaiyli ttdaaivce by letuaatmg 3lr)e aees ANMD cteoserrp rae donuf erna MPAA eecrrpost tub are ton tacviaedt by wol esllev fo agutmlaet lereeas deu to a Mg ion bnigk‘oc’l eth nea4 nclh) ntqFeeru Atcion optltaien tg—&; nsattiumoli of MAPA g—t&; peezarsoild tpso sacipytn nnerou &;tg— tvgeloa penendtde Mg kbcol of NDAM roetpcre eedomrv 5) iulfnx of aC orutghh DAMN ;—g&t ausecs nvee oemr AAPM cpoteerrs to eb stieredn noit the erbnemam :EOTN( PAAM si serepsvoni to Ca dan uttm)6aea)g l esuaBce theer era more etposrcre to snpeodr to ti, eht ecll si orme sseernipov to gltaematu

lal eht shotre a nteoincetvopim cisen ethy haev csiiefyciifcpc(ispet g)di,nals ANDM si eth lyno (lcnnhseeevinteceo miveiotectp ,)eprrcteo sah a ilnagd esti and ac , na nad hn.g.m.ece oeiemicptvt