The best I can understand, they're describing endometrial hyperplasia, a result of excess estrogen, a steroid hormone that translocates to the nucleus and binds its transcription factor.
meningitisMy thought as well but the answer says: "Binding of ligand to Nuclear transcription factor" and I thought to myself: "Estrogen Receptors aren't transcription factors.. they are receptors with Transcription Factor function that bind to the ER Element and recruit more Transcription Factors". Can anyone explain what I am missing? Am overthinking things?+
criovolyYou are overthinking it, Steroid hormones receptor is found intracellular in the cytoplasm then they are translocated to the nucleus where they regulate gene transcription. HOPE THIS HELPS +6
eve1000Could this be due to the PTEN gene being linked to endometrial hyperplasia?+
feochromocytomaThe question stem says it's glandular hyperplasia "without" atypia
It's just due to increased levels of estrogen causing the hyperplasia +4
faus305This is a bunch of scientific mumbo jumbo+1
chaosawaits^^ I read your name as "ugly chromocytoma" and if that was intentional, buena onda+1
submitted by โbeeip(141)
The best I can understand, they're describing endometrial hyperplasia, a result of excess estrogen, a steroid hormone that translocates to the nucleus and binds its transcription factor.