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Retired NBME 22 Answers

nbme22/Block 1/Question#35 (reveal difficulty score)
A 35-year-old man is brought to the hospital ...
Alteration of the thermostatic set point ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
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 +20  upvote downvote
submitted by โˆ—keycompany(351)
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Aeariontlt of the atemrioschtt set ipont is a yhhmilptoaca eossprc dmeideat by dslspagntnaior adn is edditnpneen of het iemshypttca oeunrsv tmsyse.

,B ,C ,D dan E all reurqei aeispytmtch neervs ot cliteil a sn.eopres

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pg32  anC nayeon pixelna hte cmhmenasi hdnibe inegrisvh adn eht tetsiymcahp nsoruev sse?tym +4
mdmikek89  upHhsmylotaa arslye ohuhtrg eth oocmniaut uvnreos et.sysm ouY cut eth a,rley yuo cna yonl achnge hte ctmeaorhitts est ot,inp btu het dboy t'acn .crate +1
umpalumpa  suG,y I tkinh ahtt rfo hte hvisniger aarvlnteite teh iopnt si OTN hatt hietpmtscya venres nrocolt risnvhgie alatyc,(ul I hnav'et odufn rlsaetci on pumbed ahtt asys atth vigreinhs si tocellrdno by is)tmpet.ycah eHT etaiess ayw to tknih si ttah ihts pt hsa a smiseyct itcoenifn (aak RsycisSSI-etm mntoiyamlfar sesreonp .odsyem)rn nI ISS,R tp anc veah 3;t5&Tl C ro t8;3g& ,C UBT ti si rmoe mmocon ot heav efrve anth piathyhemo.r dniegsnoriC si,th you anc aylsie -uleutor hte eiinvsrgh irelavntate. +1

Even brown fat needs SNS == release of NE == binds to beta 3 receptor on fat == uncoupling of ox phos!

+6/- apurva(101)

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 +4  upvote downvote
submitted by โˆ—qfever(67)
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pmsoHaayhlut onlioltngrc atuerrtpeme tes tnpio is eybfril dtneoinme in mtaPoah 0812 oeiindt epag 3,1 etprahC 2 III iCanrlda ngiss fo nonlmmafitia D. eFerv

goeenyPs ;&-tg maaohcpgre eslraee I1L- dna FTN -t&g; siedcaner cnsxecgoyyaoel cyittvia ni tlsahuamphoy arpraeicvusl eslcl -;g&t sceidnrea yolhutshaamp G2PE ;-t&g idares upteeetamrr est niotp

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 +0  upvote downvote
submitted by gribear(0)
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Cna ooesemn ieaxpnl why henw uyo ttncesra eht nliasp dorc rpiosure to eth eellv of itseaytcpmh fltowuo -- and oyu etg a stiysemc oteicninf -- eth poesersn is lntertaaoi fo teh hatcrsttoeim tse ?ntpio

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its_raining_jimbos  oS I ecsoh that one csebeau est tnoip si nlteoclodr yb the lupoahthmysa P2(EG dna I-1L eaietmd erfve ni the opmyth)haslua adn het rets of teh reanws hiceocs eolvivdn sotgmnhei olewb teh vllee hatt ahs bene dettsanc.re toN %100 ures if atโ€™tsh ertaacuc ogh.tuh +5
noselex  Adegre ihtw @triimb_so_nasjinig -- rveeF si ieaemtdd by lrigneta set tinpo ni poulha.yamhst All eth throe ehsiocc, sa fra as I anc lte,l inlvvoe thtmapeysic erensv dan itreh ftsfcee at ettrga g.srnao +2

You might not be able to change the temperature because you have no sympathetic outflow, but the actual "resetting" of the thermostatic set point is mediated via the hypothalamus and prostaglandins

+2/- spow(50)

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 -1  upvote downvote
submitted by โˆ—j000(17)
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i got htis itesqnou o,rgnw tbu i tkhni hwta htis situeoqn si laerly iankgs si wath phsnpea in a tycsiesm eftcii:non icwhh is eevrf

ni tsciseym fineto,nci hte tmso svbuioo gisn ot kloo rfo si a f,vere tno sserynilcea eiihsng,rv gwetanis, ehta tupdcniroo yb wonbr fta, tc.e

nad how osed efrve ?rcuco klei eoosnem elayrad onetem:nid yngsopee -;g&-t poaamcrsgeh neirgslae 1LI dna NTF hchiw srnesieca CXO iicyvtat in ploumshyahat avprislucear lesl,c eesrnaic otudrcpino of P2EG in ayphshmtauol adn eerst eht ettuermrpea tes pno.ti

i tnhik eth whelo ersaph eeclpt"om nerotanisct of eth iaplsn orcd rriupeos to the lelev fo ptshaim.cte.y." si a a.condtsitir it sutj lslet you taht etveemplnod fo a erfve ash otnnghi ot do tihw ti

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j000  edmlptvneoe of a vrfee in etmyssic tcinnfoie has tiognhn to od hitw tapsetyihcm nsvuore ol,wf os vnee ist' j,unride efrev lwoud listl .cuocr I ktihn ihst iunteoqs is utsj kaisng hwo esod freve courc in ioilffnimtnmotnna/aeic anoti.iust +1
b1ackcoffee  ,oS hwo do oyu iaxpnel eth tlcaua revef by usjt anighncg eth tosmter?hta? erFev fefc''te SI drnue tcatmSehiyp tcroln,o sutj eth hggnanci het rteeumtrepa kle(i ttrteohmsa) is mediadte by eotnsciyk and .yhtlsaumopha +2
j000  oh i see hwta oyu ,mnae wlle i i'dtdn wonk that, os nstkha orf fgarilcnyi htt.a erh,wevo dbase on your aniopn,lxtea ti lwuod siltl etg su to eht tghri renwas hchiw si "nariaotetl of ttitmecsraho ste n"pt,io otn het refev fefetc .flseit +1

So, how do you explain the actual fever by just changing the thermostat?? Fever 'effect' IS under Sympathetic control, just the changing the temperature (like thermostat) is mediated by cytokines and hypothalamus

+1/- b1ackcoffee(115)

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 -1  upvote downvote
submitted by โˆ—mdmikek89(6)
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Oaky soyb nad rlisg tsih uiqonest is iraese ntha ouy nki.ht

pysmoutaHalh slreya aiv het ihytatcsemp souernv sstmey ot lncootr eth dbyo hnew a enw tse ntpio as enbe rahceed in selt .c.ssa..uereev..ayf c..enitf.byino..

fI eht etncnocnio netewbe het smaahutyhplo dan sailnp rdco anmy(il teh ietpshytcam owtlfuo) si t,cu eht astlamuh ntonca ayerl eht odby ecaotrin of a vr,efe but the umaahpltshyo efstil can illts neachg eth ets to.pni

omoB

tinihW the ,brnia the noiotamcu sovruen semyts is gletedaru yb eth usltahpamohy. tiouAcomn ctfnnisou cdeulin lnortco fo otnrepirais, arcadic ntilgueaor h(te cadiacr colontr cr)t,een romoasvto vaitityc the( savootrmo cnt,ere) nda atirenc lreefx aoctisn ucsh sa ngiuh,ogc sz,ineneg sllioawwgn dan intigv.mo

-BE urcco sa a etlusr of a hcgaen in ste nip.to

A pnsepah ot ceusa het EB- henw a wen tse tinpo is e.drceah

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 -1  upvote downvote
submitted by โˆ—isaacyo94(13)
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nI istcmesy efiioctn,n dtnlwuo' yuo egt acsoteunu sLTDIoOAavIN e(..i sdeitubrivit h?kco)s ihsT asw ym risangnoe rfo ncoghiso B) ni siht akcwy io.etnuqs

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neilfespiritu  meSa +1


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 -3  upvote downvote
submitted by โˆ—gh889(154)
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Fomr oekeHankyhuorSond no dt:ired

ahWt teh eqtisonu si tgetgin ta is het caiephtstym nhaic swa dprea.s It was a bretleir ywa fo rinodgw i.t

ruYo nrteoiar humoaslhptay si epsinlbrose orf ocgloin seaeuftr adn si uenrd artsacmyteihpap rlntc.oo A lesoni uowld csaeu rhaetmhrp.iey

Your ptriesoro uphothlmaysa si pbrlieessno rfo neatigh whne ryo'ue lcod dna to gnereeat het eerFv posersne dan si rdnue ptstieamyhc rtlncoo. A loiesn odluw ecsau .atiomehryph

In hsti oneusqti it si mpsyil ginaks a rnoesp gets icsk, amhlyhpoatsu was adspr,e whta pes.pnha

ews:Anr hyatuaplohms llwi ltisl eb aebl ot vteeael est byod puretremeta to lbetta f.onncitie

Hnit: FI ehty gvie a eoutiqns rimlisa to stih but eerrddow to nueicdl a nsiloe fo the asyhicmtpte erfbsi or fo hte hhoasmlytpua, uyo duowl in urnt NOT eb aleb ot ateegnre a eervf nposseer ot cniniofet. Teh tlyapmsuhhoa duolw eb eelyitrn deurn parmtpicayatesh nrtoclo

hsTi adsd mreo toxcent to teh tfca hte Q aettss ahtt the siecpthystma wsa arpdes

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oslerweberrendu  So, hsit ysas hyeaitscmpt olsa aspdre adn otphluyamahs lsoa srep.da hTne tawh saw wgrno wthi siht ililancc cea?s? +1
adong  i hiktn eht tsmyacpethi tsymes is lyalcuta ipemirad cb/ tis' uct febeor ti cna .lfwo.".oatu"t aslte st'i hte ylon ywa itsh ekmsa sesen +4
suckitnbme  I e.rgae I ktinh eth toqieusn mtes si sagyin eth htsyatspcime ewer eldsi.one oNt ttha yhet erwe ped.ras +4


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