Translocation may result in failure to transcribe RNA because of disruption of a regulatory element (eg, promoter) within a gene.
The affected gene will not be expressed or will be expressed in a dysregulated manner compared to the normal phenotype
isTh hsa to do ithw nniotr lni.icspg ebRmmree GG.TA shiT mniatuot dnieudc na GA sclreo ewhre ti asw esposupd to be, so meos of thta rinnto ustj eaecmb an neo.x
I erdirntepet uqsece"en rdnosnuguir sitfr wto ensxo fo gen"e - ot mean yeht mtsu eb nltgaik utbao si.onrnt ehreT fo eht arswne hoecisc nd'to ahev mcuh to do hiwt itsonrn.
hatt aym ont be ari t,ithg tbu psehl oarnrw .ndow sAlo ningkow oems amits-aehlasB si due to svntriaa in abnloarm ilicnspg eh.pls AF( 9012 gp 3)4
olsa mreeermb ttha mss-atilaaBeh is due to opnit aiumsttno ni ieclps seist and mprooter cqeseeuns 9(1FA 4p).1g0 fI uoy aretec a atumotni ni a spelci esit ouy lwli ylrues sesm pu teh rretcco mRNA edende to eakm a otnucfnial -gblionB neroti.p thaT si how I dswrenea the iqon.stue
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$279$49As rdcsiedbe in the setquion ,etsm siht tnmotiua csoucr hitiwn an trionn a( neeg gnteems wcihh is ratiberdcns DNA;N[-Atg&]R ubt nto d)s.enatrtal NRA isicnlgp zyem)(ens rbga ANR adn pl“oo ;ti” an irontn is utc out and the xseno on teihre sedi of eth otrnni aer odai,nejd elik i:sth
txnione——1r2eonnxo =&g;t —2e1xxnoeon
iT,aplyylc stih iigsplcn ucsorc at eth evry edesg fo eht ointrn (awht I oedetdn htiw hte —“” cra.hraect) tBu in our aces, a itaomutn tnhiwi het niotrn is acsnuig ARN niglicps ezyemn ot eozgrcnie a ewn set:i hte plciers sctu nwithi the rinton inesda(t of at hte rvey e,edg sa it u).hsodl oS, ew teg hitgsomen tath koslo lkie si:th
e21xn—xtooreni—n
tTsa’h a tllyota efnfdietr mRNA oeulec,ml adn i'ts giogn ot ekam our onβglb-i oteinpr look (nda )hvaebe alwlfyu t.sraneg
$279$49