Translocation may result in failure to transcribe RNA because of disruption of a regulatory element (eg, promoter) within a gene.
The affected gene will not be expressed or will be expressed in a dysregulated manner compared to the normal phenotype
shTi hsa ot do whit onrnti pigs.lnci Rbmeeemr .GGTA shTi tnuaimto ddeuinc an AG rlscoe wrhee ti saw psdsepuo to be, os smoe of ahtt rtonin usjt ceabem na neox.
I rtenerpedti eeseuc"qn ronsungduri ifrts two nxose of gee"n - to eanm hety utms be niltakg uaobt t.osrinn eheTr fo het waresn cecisoh tdn'o eahv hcum ot do iwht i.ontnrs
hatt aym ton eb ari t,thgi utb leshp wrroan odnw. soAl ingkwon seom atlssahmaBei- is ued ot irvsanta ni amarlbno ncigilps ls.phe F(A 9120 pg 3)4
laso rbrmeeem that ela-Bstsmaaih is edu ot nipot niastmuto ni cileps istse dna roertomp sneseecqu 9(A1F 04gp).1 fI you caeter a tmtoanui ni a pscile eits oyu wlil suyerl emss up het crcrteo mARN deende ot meka a tlnifnuoca n-liogbB inropet. thTa is hwo I dneewsar eth us.tqnieo
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$279$49sA serbdiecd ni eht iuoetnsq em,ts htsi nituaotm crsuoc iwtnhi an tnirno a( egen ntemgse iwhch is betcdirnsra R]-A&[tA;NDgN tbu tno at.ardl)sten ANR lgipsnci es()nmeyz garb RAN dna olp“o ”t;i na nortin si uct otu adn teh oesnx on terehi sedi fo teh nnotir era neoida,dj ikel :hits
2x1enteonnni—x—roo =&;gt on—2eoxe1xn
,pylylcaiT htis islcngip succro at het revy eegsd of het nontri wa(th I dtdeoen hwit teh “”— eh)crrtaca. Btu ni ruo sc,ea a mutonita wtiihn teh toinrn is angcsui ANR ingplics zeynem to onirczege a nwe si:et teh islcrep tsuc ntihwi het ntnroi esdtina( fo at teh yver ed,eg as ti )hosd.ul S,o we get egoihmtns that lsoko keli h:its
2—eitre—n1noonxx
’tsahT a oaltlty efidetnfr ARNm lumeco,le dan i'ts ggion ot meka oru blgiβn-o inretpo lkoo (nda hbveae) ywalulf esganr.t
$279$49