o,S for smoe aenr,os ettstnrairnserumo is nomsietgh eI'v YAWSLA reugldtsg .wt.h.i opbbrayl bsuceea I st'wna tghuta it llwe os nreve yellra laneedr ,ti sjut dleeanr geohun ofr eveawthr a.mxe I tujs uofdn isht obo hhorutg NBIC nad sti TTA!CIFSNA 'stI fmro 0021 so thmig be dlo, btu it was gre.at You cna hsecra otughhr het boko nda dinf the rh.pcesta I prttye cuhm stuj wnte uhgrtho lla fo eht rttueoemrnnartis hact.pre h.7sNm.g/two9oi.tbhvi9:lpb0/nwcB//1wKns.n/ko

My iman stGak-al mt:taeayuawe = rjmao torictayxe tir.aentmutsorern owT yestp fo o)rpst1ee rc: rteoba,toimcp sotm fo hchiw are snipcyeratp iG wichh deasl ot rceadesde DMAN erpcetor yctvaiti dan risk fo cti,otieitiyxocx or capsptsotiyn Gq ectesorrp atth ldae to csneriea a,N+ K+, dna adcserdee mgutaetal sacsue iradnaoozitelp and eaecsdnir +M+g aitmeepncsld nda NMDA rocertep tvtcayii dna sirk fo yixotcticoexi,t adn 2 ) trcoiipoon lennhacs dicinguln ANDM nad teakaMPA/inA snnleah,c chwhi lla oalwl ifnopsniecc nitaoc nul,xif but ylno DMNA wsloal Ca++ finxlu (adn ylon ni a elaogvt nnedetedp nnaerm efrta nicufesfit tledozoianprai sah sadldpcei teh hoirintib ++Mg noi in eht nhencl.)a

ABAG and glyecni = irihotiybn iautrmtnto.rseensr ) 1 AG-AAB dan CGABA- = oictoiropn cnnhalse atht dael ot xeulf fo C-l, dna pedites hsit gciusna altipoiadr,ozen eth neornu sltli stysa bolew neigstr eioantptl. AAGAB- iigdnbn tsie for rtabrs,uebiat teosir,ds ,BAGA dan ipoinocxtr = sdenii orep fo .ahcennl A-AAGB nbiidgn ites fo ibiespeonneadzz = otusdei of orpe of elac.nnh ) 2 cyenlGi laecnhn is a eryv lirisma Cl- luexf ah.nnecl )3 GBBA-A is a bmpctatorieo cnhanel ahtt isvettaac Gi gnliaed ot deedcaser MPcA ichwh vstaactei exulff K+ nclehsan dan tnbiisih a+C+ ulnxif clhasnne eiaglnd ot aairtlirnehzyp.opo

ncieoBig eainms = asloehetcniamc oamidenp o(oirnconatid of body ntomvme,e da,rewr itaoominvt, efn),eneitrocrm neienheinpropr sp(el,e weseuaf,nskl an,ttoniet dgneief vahboi,er eeinneiphrp (loswet trtninocnecoa in )S,CN supl esoonrnti spe,le( elswnsauef,k osredi,esnp ai,ntxey uasea)n nda mhsteinai suaa,lro( tt,ontnaei elyl,gra sestui aegdm,a nda aym uflnineec bolod brina )wo.lf v,iulsobOy lal of hsti si in idnoiadt to arcnrgedei outnnsraiermsnois dan ,ltghif trfgih, adn thfgi eseo.rnsp

ATP adn oterh rsepnui = otixcrayte siimnntssa,ro e-daosceerl tiwh eohrt lcso-lmelumael rne.oturrietmatnss dinenoeAs s'nit lsiccsayall nriecdesod a rreaeonmtttisunr becaesu it ntsi' oddeeesr/erlast ni aC++ teneepddn naerm,n tbu ddvriee fomr APT rfoebe naivhg na yeattocrxi ta.noeplit

ylcthoAicnele = jroma tantunirteersmro vloevndi ni nrominranestuioss avi nmuarics nad inictcnio tercrs.peo

Ppitdee nusntmtasertrieor = ncomoylm adreseel sa rieppptdeo elargr rcserpruso tath aer daeeclv by psecfiic zsynmee ttha erew in teh meas etasrrttirenomnu iesvlec upon e.srelea Five ystpe = gurin/tba eisep,dtp diooip pietp,des aptiryuit p,petdsi iopmhchalyta aegnilres omh,nesro adn esoth nto sdsiefcia.l xEapslme = posucerrr atth gesvi rsei to ueastnscb P ahm,ispop(pcu co,xnteore adn TIG dan ledsaere orfm slalm tredmeai SPN C sferib htta rnstatmi naip nad petrrtueame iofinnrao,tm plewoufr opsehnevti,y niitbhdie yb oioipd deppe,s)it ionueknirn ,A neeodetippur ,K adn eiopedneptru ,mamag adn iioopd despptie ndciginul tanpl lalaksdoi (iekl )mneoriph, ctytnehis ipoiod sv,rdeitvaei nda ,nhirpnsode i,snhdnoryp nad snhnaip.kele nI agelner pooiid espepdit rea estnperdass (.ei. aaaleinsg acmhm)s,ien eivdnlvo in xelpmco oehrvibas slxeu(a ctnitoara,t gis/agruimessisvseebv iehr,saov)b and emlicdtapi (hgouth not ftniiive)de ni thiyicsaprc drr.seisod

aOlerl,v rteentsrustaonrmi = tpey eypts: ml-msaeeculoll namteisrstrt nad ueoe,idertpnsp rewhe sleecsam-lmulol maesritnsrtt era eastrf and amteedi apdir ayncitsp inmtosnasrsi (.ie. aodrengn SNS gi/fii/grhlhhftttgf iquck peo)snes,r ehwre as ipsdueoepertn ngl(oa htiw cbiolgoi eainms nad mseo mllas lemceulo trmttseinasr) are orwels nda mdetiae gala,urd dolnorgep sieuinrtrososnnm.a

eSmo iepucrst: hsutw/mr_m/oktphiltrnwntdhrwveoesbteemrade/opn_vterfi/duoapakunpetuii.e:/..s_c, pGgprtno.ee-r/bbleft4fassibr1.20ei//1rgdis//pu5880p--r1lRcaosdccwduciPt3m-10ep4BTf1o-l696Bei:eg6aaAarg/h3hswa2r/0Autea-d3eawni-47osgb6e0tne2rf-3trh, nda 3/-twgoda#aehdbl;esgxg3c1we=U7id9//f-irsn._&5ptdgae-ae2e1b18t/eh20gxl-6bwr=ndtnh-la-b-0416/siepawa5fmfu.f.:-bri/alet

ghoTu onuq.esti

eRllca taht tMmienane reh'sil(ezma gr)du is a NADM eRpcoret iatostnngA thta hepls epernvt cyootitxictex by koglncBi Ca2+ rnyte. sThat' who I erbmmree tis.h

• A) AA-GAB poestrcer elt lC- in
• B) nclGyei is euds in eth aslnip cdro sa an niirybitho maiettersnun;rrot soal ltse Cl- in
• C dna )E etiobMtrcaop agtealtmu ecrsrepot era npirt-Geo dloeupc
• rTreoehe,f hte nloy hingt ahtt duclo tel C2+a in si NDAM erptrceos

NAMD rpsereotc in ihst acse are ingeb used rof gnlo temr nattoetniiop itihwn teh arbin nda tuo fo lal of treeh soicceh lnyo hsti toeerpcr ssue +aC

uoY anc snraew yb coprses fo neto.imliian Cp"mitioeetv netot"irsican eamsk yuo inkht imryuatslot .NT sosCr uto ABGA dan ncyei.lg nI eth otxcer so utag.eltam etbpatorcoiM dlwou mean herste' ncdsoe ssesgerenm olveindv adn teh rcerepot ldwou nto rmtsatni .iacmulc enHec NM.DA

eusd ni nlog mret iottonneaipt uglng,ae(a oey)mr,m May aols paly a lore ni egen titorransnicp ni unrneso

)1 ADMN is a utteGaaml eecrtpro py2t)eusb APAM is a tsebupy fo DMNA htat is iilialytn eitvaadct yb aaetmlugt ea 3ere)ls NAMD tprroeesc era unodf eanr PMAA srerecpot tbu era tno aadveittc by wol seevll fo taamlgetu lresaee due ot a Mg oni b’ck‘onlig het e)lh4cna n Ferutqen otniAc altpioetn g&;t— alomsintuit of MAAP g—t;& saplzoreeid stpo atpciysn eunron ;&—gt ategovl npentdeed Mg lockb fo NDMA crporeet edomrev 5) uxnifl fo aC hhruotg ADMN t&—;g cuseas veen erom APMA petrrsceo to eb nsrieetd tino eht anemebrm NTO:(E PAMA is rnpveioses ot Ca dna g)e ut6mtla)a eseuacB hrtee aer orme spretecor ot dnopsre to it, eht lcle si emor rviepseons to attumagel

all teh rhsoet a evioipmctonetn eiscn they aevh icieitsc(pciyscfefpi )ndal,igs ANMD si eht oynl hei(lotensecnevecn itviteceomp ce)e,prrto has a ilangd itse dan ca , na dna ..eg.mcehn evttpicemio