effect of glutamate antagonist on pt with acute cerebral infarction = targets NMDA receptor
decreases calcium entry into neurons = decreased excitotoxicity = promotes recovery from acute cerebral infarction.
huogT ieostu.nq
Rlleca ahtt nnMiaeemt melhzai'e(sr )udgr is a DANM ecpotrRe asAtitgnno atht splhe tprneve tixieocctyxot yb gokBcinl a2+C tnyer. haTts' hwo I eeembmrr t.sih
a picture for better understanding https://2e.mindsmachine.com/asf04.02.html
^ link is dead :( (they published a 3/e) but here is the re-route to the new site if anyone wants to dig in https://learninglink.oup.com/access/watson3e-student-resources
ADNM roepetscr in hits csea are bengi eusd rof ogln emrt aopitntieton ihtiwn hte nraib and otu fo lal fo hrete cesohic only ihst rperotec seus +Ca
I ckidpe NDMA aucesbe t’si luits,trmyao tub si rtehe yna erpeed aesnor rof hsi?t
uoY nac aewnsr by oepscsr of laomi.niteni "eetitiCopvm titsane"onicr ksame uyo hitnk tryistlouma N.T sorsC tou AGBA nda geyn.cil In teh ctreox os muetatla.g atoborcpeMit udwlo enam eh'rste scneod esngsmeser dlnevivo nad eth cortpere uwlod nto srtmntai lc.mauic ncHee .NMDA
desu in gonl emrt tietotoapinn ,eagalung( emy,orm) yaM lsoa yapl a relo in gnee tcironpatirsn in rosnnue
1) MNAD si a aumateGlt cpreorte )2tspbuey AAMP si a pestyub fo DNAM htta is litiiyanl avdeattci yb gaueltatm e3 salre)e ANMD crpterseo aer nofdu aenr PAAM oceetrprs but ear tno aettcvdia yb low slelev of gmaulaett seerela deu to a gM ino lcgbnik‘’o hte nn4a)hecl tqnereuF ctoAin lteotpani t—&g; ulnisitaomt of AMPA g—;t& rdelpszoeia sotp acpniyts enurno &tg—; tgoavle edtpenned gM ckblo of DMAN potrecre redevom 5) ixlnfu of Ca uohghtr NDAM ;t—&g eussca eevn emor AMPA prrtesoce to be tdesrien iotn eht nbmmreea OE:TN( APAM si ssepenivor ot Ca nad tm)l)ae6u gta esucaeB hreet era eorm rpsrceoet to nerspdo ot ti, eht lcle si remo invsepesro to etmutlgaa
lla teh hostre a oeonmiventtpci nscie yeth vaeh ci(cfifctieispypcise sil,gdn)a MAND si eth loyn tenc(enohivclesnee tcioetmvpei pe,)cerrto hsa a anldgi iest nda ac , na nda e.g.nech.m ettomciivep
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leytoAhncelic = omjra autsetmnrirteorn nedvvlio ni ntoimousinrenasrs vai niarcsum and inocntici rtposcer.e
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