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Retired NBME 22 Answers

nbme22/Block 1/Question#35 (reveal difficulty score)
A 35-year-old man is brought to the hospital ...
Alteration of the thermostatic set point ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
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 +20  upvote downvote
submitted by โˆ—keycompany(351)
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onattrliAe fo hte tihtertscamo tes tniop si a htplamciohya osrpsec dmdtieae by aspiadnosntgrl and is nendpnitdee fo eht pcmeihyatst uroevsn tysems.

B, ,C ,D nda E lal eqieurr pyttmscheai enrsev to tclliei a osrn.eeps

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pg32  Can nyaone exlpina eht icensammh nibhed gheiirnvs dna eth eactsthipym svoerun ytesms? +4
mdmikek89  aohltysHuapm lreasy htrough eth toaonucim soeurvn sse.ymt ouY tcu hte era,yl you acn ynol caheng hte omcrsattethi ste ,nptoi btu eht ydob ct'na e.ctra +1
umpalumpa  ,yGus I thnik tath orf hte hvgsnerii tlntaeriave teh niopt is TON htat pestiatymhc nesrve ctlnroo hvsniergi lcuta(ya,l I enhatv' unfod trsiealc on bdpume ttah ysas atth sniihvreg si lcenrolotd yb smtcyephi.)at THe asitese way ot hknti is htat itsh tp has a ssymiect oncieitfn aka( e-ytSiImcSRss omalftryiman pneserso er).ydmsno nI ,SIRS pt nac ehav l&35;Tt C or g3;&8t ,C TUB ti si eomr cnmoom to vhae frvee nhta emhirpato.yh iernsndCgio ti,sh you can yisael ot-uuerl hte rnviesigh rtvtleni.eaa +1

Even brown fat needs SNS == release of NE == binds to beta 3 receptor on fat == uncoupling of ox phos!

+6/- apurva(101)


 +4  upvote downvote
submitted by โˆ—qfever(67)
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utomhyaalpHs ignolntclro rmtapteuree ste itopn si elifybr nnomedeit ni aaPthmo 8012 netdioi egpa 31, Ctherpa 2 III nadalCir igsns of itfiolamamnn D. evrFe

noyeegsP ;tg-& hrepcaagmo easelre L-I1 nda FTN t&-;g nceiaresd eelygcyonoacxs yiitavtc ni sophlmyhatua elruvsracapi clles >- siancreed ohaysutplahm GPE2 ;-t&g sidare tepreatruem tse noipt

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 +0  upvote downvote
submitted by gribear(0)
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aCn eoemsno lxpneia why hewn ouy sctnaret teh nslaip droc uriepros ot teh levle fo ttcyihmaspe tlfoowu -- nda oyu etg a smesityc nnteiocfi -- het esopnser is atnaeiotrl fo het chorettimats ets ?pniot

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its_raining_jimbos  oS I cheos ttah one busacee ste tonpi si elclnoortd by hte lhouyahmtsap (E2GP nad I-L1 dieeatm evefr ni the pm)thlasuohya adn het srte fo eht swrean ocshiec vvidlneo eimotghns blowe the evlel taht has nbee eredns.tcta Not 0%10 sure fi htaโ€™ts ractauec htugho. +5
noselex  rgdAee wthi _i@sansinmjgbr_oiit -- eerFv is didmatee yb nraeiltg est ioptn in pshhaatuy.mlo All eth reoth oc,ihcse as rfa as I cna el,tl velnovi pyciheasttm ervens dna ethri stfecef at garett rsagon. +2

You might not be able to change the temperature because you have no sympathetic outflow, but the actual "resetting" of the thermostatic set point is mediated via the hypothalamus and prostaglandins

+2/- spow(50)


 -1  upvote downvote
submitted by โˆ—j000(17)
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i otg thsi usnqteio n,orwg tbu i itnhk wtah hsti utqiseon si yralle niagsk is tawh aesphpn in a yssmietc cntifo:ine hhiwc is efver

in cesiytms inetnioc,f eth mtos osibvou sgni to kool rfo is a er,fev ont ilyeesrcsna ,vshrnigei wsiag,ent heta pctroduino yb bwnro ,taf te.c

nad hwo sdeo efver cc?oru elki onesemo arelady o:detnemni nopsgyee -g-;&t gpamarcseoh lesrenaig L1I dan FTN which esncriase OXC tiiycvat in oluhashapymt aalcprurevis llesc, ncisreea norcudipto fo GE2P in oahaltymhsup dna teres the eprtetamuer ets inot.p

i inthk the weloh seprha "mlpceote strneoaitnc of eht pnlias rodc pseruori to eth lleev fo mthtseya"..pci. si a atoinsrtdi.c ti sutj sllet you taht eemtolnevdp fo a erfve has nntgoih to do htwi ti

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j000  npvldeeeotm fo a vrefe in icsyetsm onintecif has itnohgn to od iwth steaipthmyc svoreun ,flwo os vnee 'its ,riujnde erfve wdluo llsti .cucro I tkihn htis eituoqns is tjsu giakns how osed erevf cucro in ntnlimmtcfoaeinnoiaif/ unttisioa. +1
b1ackcoffee  S,o ohw od oyu inxplae eht taualc vrfee by tusj ihngcgan the tos?ehtrat?m Fvree fetc'f'e IS undre ctpSmyaieht cnlorot, sjtu eth naghcgni teh petaermteru kel(i mtaseo)trht si iaeedmtd by etyoikcns dna maylshpao.uht +2
j000  oh i ese wtha ouy anm,e ellw i ni'ddt wnok h,tta so sathkn rof agriylncfi hta.t evrwho,e esbda no yuor paexnaoln,it it ldwuo tsill teg us to teh igthr ewarsn hiwch si to"aantelri of moaecttrtsih tes oi,tp"n not eth erevf tefefc si.lfte +1

So, how do you explain the actual fever by just changing the thermostat?? Fever 'effect' IS under Sympathetic control, just the changing the temperature (like thermostat) is mediated by cytokines and hypothalamus

+1/- b1ackcoffee(115)


 -1  upvote downvote
submitted by โˆ—mdmikek89(6)
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ykOa bsyo dna lrigs ihts nouqeist is iesear ahnt uyo tkh.in

mlyasaputHoh yrslae iav hte tchetpmsayi nvoseru semyst ot ltrcoon eht doyb nweh a wne tse ipotn as enbe aecedrh ni tlse ...eyr.seauefv..acs cfbe.ti..ino..ny

fI eth otnicoencn etnebew teh hpayhsoumtal nda sliapn rcod nyima(l teh psaytcmiteh olwfot)u is ,tuc het msthaula ontanc eryla teh byod coreitan of a fvree, utb the thapolsyuham lsteif acn llsit ancheg eth ste otpni.

Bmoo

Wintih the ,airnb eth tuonimaoc uvnoser tessym si uladteger yb eth hamaphylosut. otAonmuci nisntcouf ceulidn ooclnrt fo onsa,iepritr arcciad gairlteuno te(h acrciad coonrtl ecet)n,r taroovsmo ctaiyivt ht(e otrmvooas )nr,etec nda anrceit erlfex itacson hcsu as g,ciohngu is,negezn gllonsaiww dan tiimg.vno

BE- uccro sa a tserlu fo a gehcna ni ste ito.np

A phnspae to aesuc the BE- ehwn a wen ste iontp si ee.rhdca

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 -1  upvote downvote
submitted by โˆ—isaacyo94(13)
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In mctsysei tnfi,oecni 'dwlotnu ouy egt custaonue ILDANTvOsaIo e(..i tubvitedirsi k)hc?so shTi wsa ym norgnseai ofr ogihoncs B) ni tihs wcyka o.entusiq

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neilfespiritu  Saem +1



 -3  upvote downvote
submitted by โˆ—gh889(154)
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rmFo hHkeuyrodooSnakne no reidtd:

tWha hte uisnqoet si gignett ta is hte yiheasmtptc aichn swa ad.eprs It asw a beerltri ayw of wirgnod .ti

ourY trneoari ushyomhtalap is roesbelnips orf golcnio tafueesr adn si nuerd pctapsahimyarte lt.noroc A noiesl lwudo sauce rh.ayephtiemr

Yruo oroepstri oatlahyumsph is rpeeiosbsnl rof ahginte wnhe eour'y odlc nda ot enaertge hte ereFv enserosp dna si ruend yipcmastthe .otlncro A eoinls lduow sceau ymohtai.prhe

In hist uqentsoi ti is pmyils snkagi a nreosp tsge kcs,i spoylhmuahta saw a,depsr htaw spa.phen

nwr:Aes myhtoaapsuhl ilwl itlls be elab ot eeeltav tes bdoy trtrpueeeam to tlbeat ftnnocie.i

:inHt IF thye iegv a tuqsnoei mlsriia ot isht tub odrderew to diucenl a silone fo eth tsptyamheci fsibre or of the tysomlaphhau, you odluw in utrn OTN eb aleb ot gatereen a eerfv sneoespr ot ice.itnfon ehT huapmyalthso wodul eb rlteneyi ernud aaratetyspcmihp nortolc

Tihs dasd mreo txectno to eht tcfa het Q saetts htta eth mhaiestscpyt was seapdr

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oslerweberrendu  ,So htis sysa mtctyisahep loas draspe adn uopaylshamth losa rdsa.pe Tnhe twha was rowgn twhi hsti iinclcla ?c?aes +1
adong  i nkith eth msteticayph yestsm is tylcuaal aidieprm b/c i'ts tuc eeofbr it acn wf."l.ot."uaot estal its' teh yonl ayw sthi askme esnse +4
suckitnbme  I gaere. I nkhti the eousitqn esmt is giasny hte catmsthypies rwee isnoedle. oNt taht yhte erew pre.das +4



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