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NBME 22 Answers

nbme22/Block 1/Question#25 (48.5 difficulty score)
During an experiment, a 22-year-old man ...
Arteriolar resistance: decreased;
Capillary hydrostatic pressure: increased;
Capillary filtration rate: increased


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submitted by its_raining_jimbos(22),
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oNt 100% urse on isht eon, utb eeh’sr owh I edrppcaaoh :it aimtneihs scesau alirreta dltiiaon d(=rdeceesa teirrroala t,sse)cirnea utb all fo thta dlboo sah ot go oesehwerm encis ouy own heav meor bdolo fgloiwn ghohurt the raersiet nad atht srehwmeoe is the aielriclsap esi(dceran payrcalil harctsiyotd e.)rrupsse eHmtinsia cessau rciaesnde ipertaeymlbi of eht prsopca-lyalti leevusn e(no fo r.D Sa’satrt trevifoa )fsatc so u’yod hvea eesricadn rapliycal tilanfirto .aetr

taediggity  Totally agree, arterial dilation--> increases blood flow into capillaries/increases capillary hydrostatic pressure + increasing permeability of the post-capillary venules= Increased Capillary Filtration Rate +1  
makinallkindzofgainz  I love you explanation, but I don't think filtration rate is dependent upon permeability of the post-capillary venules. I think the filtration rate is increased simply due to the increased blood flow; this is similar to how increased renal blood flow will increase Glomerular Filtration Rate (GFR). +10  

submitted by link981(160),
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aiismtHen aucess eioarertl vidtlaiono,sa cagisnu a ulupbid fo dbolo ni hte aiple.arislc Teh csrdnieea bldoo in het lrlasipiaec lwli uaces hte rpuseres ereht to srei. torFaiintl is enddteenp no e,urrpses eht irhegh eth uess,prer eth orem hte .lriitatnfo

bmmeereR bldoo f:lwo invse to nuevesl ot aeacprillsi to olariseetr ot rrtseiea

yb_26  agree in all, except the blood flow - it is right the opposite [] +15  
link981  I stand corrected @yb_26. Brainfart moment 🙈 +  
rockodude  lmao including a link to a teachmeanatomy page on basic blood flow +  

submitted by moneysacs(2),
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saintmHie asceus a eerdesca ni dityohsatrc eerrusps g(te thi,s tsi’ a tvaasdoo)lir utb htne eascus na serienca in pryiacall idcsttayohr rruesesp? akOy,( htis si woh it seasuc maee,d I .s)gsue esoD yeoann etg who iths atlyuacl r?sowk

its_raining_jimbos  Not 100% sure on this one, but here’s how I approached it: histamine causes arterial dilation (decreased arteriolar resistance), but all of that blood has to go somewhere since you now have more blood flowing through the arteries and that somewhere is the capillaries (increased capillary hydrostatic pressure). Histamine causes increased permeability of the post-capillary venules (one of Dr. Sattar’s favorite facts) so you’d have increased capillary filtration rate. +  

submitted by alexb(47),
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htaW yeht amen by ft...tlrnaiio

Fldui cosimerpd fo rwtea nad sctleo,eteryl whti a eryv mlsal nmouat of onetipr adn rheto lu,eocrmlecmsoa ymranoll elasve laascerplii dan lsmal aasplrpycltoi suneelv by a rsosecp ealcdl .fitorntali titrianlFo si rmpiyilra rinevd by eht illrcpaya ctsiotdayhr eep,usrrs and the otuamn eerfitdl erp tnui itme is oyindalaidlt nuclefneid by the miryelptebia of hte leesvs wlal eleutdni(moh nad nbematse ne)ambme.r hTe fidul tath tfsrile ntio eth sisute wolfs hiiwtn hte ealelucntrrli scpae (hte tisre)nmittiu dan mtos fo ti is aeoebrsbdr ta het lnuvrea dne of iceasplarli ewehr eth yrstitcodha erssruep is .weorl emoS fo eth edltfire idful is nkaet up yb litcmpayh ssseevl and etendrru to hte ioiucnl.ctar

submitted by azibird(177),

Histamine decreases arteriolar resistance, but I guess not capillary resistance.

ΔP = Q × R

In the arteriole, resistance decreases, so flow increases. In the capillary, resistance has not decreased, so the increased flow they receive translates to increased pressure and filtration.

submitted by atstillisafraud(199),
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setainHim saecus raallycpi eroliarart oiadilnt (escedaer nanre)cssieatece(risd sseuperr in the rplacaiyl cubeesa eeestnfrf einmra eth smae )siez tmHiiasen losa asceerins alriplcay imeyplrbe.ait