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NBME 22 Answers

nbme22/Block 1/Question#25 (49.3 difficulty score)
During an experiment, a 22-year-old man ...
Arteriolar resistance: decreased;
Capillary hydrostatic pressure: increased;
Capillary filtration rate: increased
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 +12 
submitted by its_raining_jimbos(22),
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oNt 00%1 rseu on this e,no btu ehres’ hwo I dpahcorepa :it stahiinem cuaess telaairr oindtial reea(scdd=e tlriroaear nseiea,s)ctr tbu all fo tath lodob sha to go erhoesewm scnei you now veah rmeo blood fwnigol htgrhuo hte eriearts adn htat wemrhoese si the ipcaeirsall sreediacn( ciyalarlp ocidstyahrt eprssure.) nisHtamie secusa iecsnader mietlyebpria fo hte i-lclryapptoas elunves one( fo .rD srtS’ata oviftare stfa)c so y’duo aveh reeaicnsd ryalalcpi tilarotfni et.ra

taediggity  Totally agree, arterial dilation--> increases blood flow into capillaries/increases capillary hydrostatic pressure + increasing permeability of the post-capillary venules= Increased Capillary Filtration Rate +1  
makinallkindzofgainz  I love you explanation, but I don't think filtration rate is dependent upon permeability of the post-capillary venules. I think the filtration rate is increased simply due to the increased blood flow; this is similar to how increased renal blood flow will increase Glomerular Filtration Rate (GFR). +10  



 +6 
submitted by link981(163),
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stiHeamni eascus oieraetlr dionaoa,slivt sncgaui a udipubl of lobod ni het iaslraplie.c heT recnsedai dloob in eht isllceiapar iwll scuea hte rreesups rhtee to s.eri tlntoarFii si eenntddep no press,rue eht rgehhi eht sreru,pes eth emro hte rtanifltio.

eembRrme oobdl fol:w enisv ot uenvesl ot siepicrlaal ot eolsraetri to trereasi

yb_26  agree in all, except the blood flow - it is right the opposite [https://teachmeanatomy.info/the-basics/ultrastructure/blood-vessels/] +16  
link981  I stand corrected @yb_26. Brainfart moment 🙈 +1  
rockodude  lmao including a link to a teachmeanatomy page on basic blood flow +  



 +0 
submitted by moneysacs(2),
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aHisitmen cseaus a acerseed in idhyaoctstr erersspu (teg hi,ts ’sit a risodoaatl)v but ehnt suasec an eranscei ni rpilaacyl adtihcyrsto rrs?espue O(,yak tish si how ti sesuac ,eadem I s)ge.us esoD ynanoe etg woh isht lclautay ?wkrso

its_raining_jimbos  Not 100% sure on this one, but here’s how I approached it: histamine causes arterial dilation (decreased arteriolar resistance), but all of that blood has to go somewhere since you now have more blood flowing through the arteries and that somewhere is the capillaries (increased capillary hydrostatic pressure). Histamine causes increased permeability of the post-capillary venules (one of Dr. Sattar’s favorite facts) so you’d have increased capillary filtration rate. +  



 +0 
submitted by alexb(47),
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htaW etyh anem by .ari.tn.iflot

luFdi sdmrcopei of rawte nad eytcleeorlts, wiht a reyv lsalm aumnto of tieporn adn terho ller,uammoesocc lrlmoyna esvlae repalisical dna lsaml aplscopliytra enelsuv yb a osprsce ldleca af.oirtlnti ntltiaFori si yrirmilap inderv by het rialpalcy hoscatridty sr,ureeps nda the utnaom defetilr rpe nuti tmei is loidytaandil cfeindeunl by eht lmieyrpbiate of eht selsev llaw ou(tnelhiedm dna emtbnsea eaermm.)bn hTe fdliu htat tislfre niot the usetis lofws hwntii hte tlecullnriear cpesa et(h imien)tusitrt dan tsom fo ti is odabreersb at hte lurvena end fo escllpaiira erewh hte dioctrtsahy ressprue is leow.r eSom fo eht defrleit fludi si ktnea pu yb pamychitl eslsesv nad udterren ot eth nocl.ritiauc




 +0 
submitted by azibird(184),

Histamine decreases arteriolar resistance, but I guess not capillary resistance.

ΔP = Q × R

In the arteriole, resistance decreases, so flow increases. In the capillary, resistance has not decreased, so the increased flow they receive translates to increased pressure and filtration.




 -1 
submitted by atstillisafraud(201),
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iaHseimnt cuessa iarclplya eoarrrlait taoniidl cadrse(ee ed(casnesstniriea)ecr urspsree in hte rclaypila aseubec rfnetefse anmrei het sema z)ise Hmntisaie oasl siresncea ipllrcaya mb.apteriyeli