Question asks about the cause of the enlargement of Lymph nodes .. Lymph node Paracortex enlarges in an extreme cellular immune response (paracortical hyperplasia) against virus infected cells (FA20.Pag 96.) T cells regulate cell- mediate immunity ... CD4 T cells specifically is the DIRECT Cell Immunne response. CD8 T cell is cytotoxic.
Mycobacterium avium complex infections are a common opportunistic infection in patients with advanced AIDS (CD4 count <50).
submitted by โsympathetikey(1600)
CD4+ cells activate B-cells which form follicles and cause enlargement of lymph nodes. Therefore, in an AIDS patient, to enlarge the lymph nodes, the CD4+ dysfunction must be resolved.