sA ebdersicd ni the stoueniq smet, siht atniuomt rccosu wntiih na oninrt (a gene tmgseen hwhic is stcnbdirera ]NRt[;AN-gAD& tub ont ats.tnlder)a RAN lcsgipni ezms)(yne rgba ARN dan ol“po ”i;t an tnnori is uct uot adn the esnox no hriete seid fo eht irnton ear jadidoe,n ilek stih:

—enoonix2rtnx—eon1 tg=;& x—o2e1nnoxe

aiyyclTpl, siht ilncpgis oscruc at eht ervy egdes fo hte ointnr w(hat I dnedeot ihwt hte ”“— atar.)hcrce tBu in uro cea,s a aunitmto thnwii the nrnoti is gnucsai ARN ligpinsc ymznee ot ciezeorgn a wen i:ets teh slicerp utcs witihn eht itnorn naesidt( of ta eth eyrv ,eedg as it u.sd)loh S,o we teg emnoistgh thta oslko keil it:sh

n—oxneioxn2t—1er

s’aTth a otallyt itefdnrfe NRmA emol,cule dan 'sti inogg ot kmea ruo -βbliong ntpoier kool d(an v)heeab uawyfll ars.engt

shiT has to do wtih onintr ingpc.sli emRermbe TG.AG isTh anuimtot icudend na GA lercos hweer ti swa opusepds to e,b so emso of htat nnirto ujts eemabc na .enxo

I ieprttndeer eceuqnes" rduninusrog siftr wto seoxn of gen"e - ot amne etyh tusm be knlagit tuboa .iontnsr Terhe of teh naersw shceoic on'td hvae cmhu to do iwth rosntn.i

• esmiessn toaiutmn ldwou heva ot eb in hte xeon to cseua ncegah ni nmiao dca.i
• idnltlaaeyoyonp is ta eth ned fo het RmNA
• niitiibhno of cpileitoran si NAD

ttah yam not eb ria hgi,tt tbu elsph raowrn onwd. oAsl ngonwki omse lts-aeBsaaihm si ude to sntaariv in araombnl piscigln .phels (FA 1029 gp )43

olas brmemree taht Ba-elstaimsha is deu to tniop oasmutitn ni lpecsi eists dan treormpo qcueesnse (AF19 10p.)g4 fI oyu eatcer a natioutm ni a clispe tise uyo llwi yrsleu sems up the rrtccoe ANmR eendde ot kame a cfauinntol oglnBbi- .npoerit htaT is woh I nawedres teh ut.snoiqe