Translocation may result in failure to transcribe RNA because of disruption of a regulatory element (eg, promoter) within a gene.
The affected gene will not be expressed or will be expressed in a dysregulated manner compared to the normal phenotype
sThi ash ot od wiht otrnni ngicl.ips Rmmereeb TG.AG iThs tountmia nddcuie na GA coselr reewh it aws uesdsppo ot be, os esom of taht notnri tsju eamcbe na x.one
I teepnrterdi s"nuqeece oundsrgnriu isftr wot sxone of "eneg - to mena htey tsmu eb ilatkgn otbua .stroinn heeTr of the wnesar eohcsic 'todn haev chmu to od wtih rinon.ts
htta may ton eb ira ti,thg btu hleps rornwa d.nwo lsAo ikgwnno emos -tlimsshBaeaa is ude ot savnrtia ni rbnoamla npiilgcs lph.es F(A 9120 pg )34
laos beermmer ttah -eslasahBimat si deu ot tinpo mnstiuota in cpiesl tesis nad trpmreoo ueneqsecs F91A( 0)g4.1p fI uoy tcreae a utmnotai ni a plesic iest ouy wlli suyelr msse up eht orctecr ANmR dneede ot eakm a nnultocfai o-nBbigl nr.opeti That si owh I aerdsnwe eht i.uonsqet
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$279$49sA edercsibd in hte sqtunieo ,etms tsih atonmiut osuccr wthiin an nrtion (a ngee gtemens cwhih si nadsecribrt tAgNAND&-;R[] ubt otn trel)sntd.aa RNA csnpgiil y(ns)emez bgar NRA dna ol“po t”i; na tinonr si ctu out dna het xeson no tiehre dsie fo het tnnior aer ijed,oadn ilek i:sht
xnxo1oe2—nt—eoirnn ;g=&t o1exn—e2oxn
yTa,pclyil hsit gslciinp orcscu ta eht very seegd of eth onritn a(twh I dodteen thiw eht “—” trraehc)ca. tuB in uor a,cse a mttniauo niiwth eth ointnr is nasuicg ANR igiplncs nyemez ot cinrzegoe a wne set:i the selripc scut nihwit hte intron dnstaei( of ta eth eyvr dgee, as it u.sohl)d oS, we etg niehgtmos ttah okols elki tish:
nnn2e1xeirx—oo—t
htsTa’ a ttoyall eiftrednf NRAm lleou,ecm nda st'i ignog to akem oru gnbilβo- pioenrt oolk n(ad eahb)ve wafuyll n.sgaret
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