Translocation may result in failure to transcribe RNA because of disruption of a regulatory element (eg, promoter) within a gene.
The affected gene will not be expressed or will be expressed in a dysregulated manner compared to the normal phenotype
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$279$49sA csrebddei ni hte ieusonqt mets, itsh tuntaoim csocru ihtwin na nrnoit (a gene tegnsme chihw is scritrndbae D&-]gANAtNR;[ utb ton aratln).dtse NRA piiclngs sey)nmze( rgba NRA adn “polo ;t”i na nrtino si uct uto adn hte xenos no erithe isde of eth rnnoti era ,enjaddio iekl :isth
—i2—oxn1eoxenntron t&;g= —on1n2oeexx
p,Tlaycily hsti lnsciigp ouccrs at the rvey eegsd of the ntrino ahwt( I denetod tihw eth “—” ahrrec.)tca But ni ruo aces, a oumtiant ihtniw hte rntoni is scuaign ARN sncigilp zenyme to iogeezncr a enw tesi: the irspcle ucts tinwhi eht ntonri sdia(net fo at the vrye dg,ee as ti hd.olu)s o,S we get nistoehmg that osklo klie si:ht
—tonri1e—oexn2nx
h’tTas a ytllaot nierftdfe ARmN celuo,eml adn tis' gigon ot meak uor glioβb-n orntpei loko nd(a avb)ehe lwlfyua nsgetr.a
$279$49