Translocation may result in failure to transcribe RNA because of disruption of a regulatory element (eg, promoter) within a gene.
The affected gene will not be expressed or will be expressed in a dysregulated manner compared to the normal phenotype
sThi sha to od itwh onrtin .lsicipng reeRmmeb .TAGG Tihs intuamto deiudcn na AG cesorl herwe it was ppeosuds ot be, os oems fo ttha rinotn ustj embaec na no.ex
I eiptentderr uecsnee"q usgrnindour ifrst owt xoesn fo en"ge - ot aemn etyh muts eb linkatg utboa osn.rnit Trhee of eht aswrne hsoceic 'dnto heva uhcm to do thiw ninrots.
atth yma otn eb ira ,ihgtt tub phlse wrorna .owdn Aslo nowgikn emos alismtBsaea-h is ude ot aviartns ni mnolraab igniclsp lhe.ps (AF 1290 pg )43
oasl meermebr ahtt amasehlti-aBs si ude ot onitp isotamnut ni pseicl etiss and ooterpmr nqsuceees A1(9F 0)1.g4p fI ouy erceta a numtatoi in a pcleis stie ouy wlil ulsyer msse pu eht tercroc NmRA ddenee to eamk a floncinuta oBbil-ng ieto.npr tTah si owh I aeedwrns the iqose.utn
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$279$49As idbcderse in eht esoqutni m,tse hist uttaomni osrucc tiiwnh an niront a( egen metnegs chhwi si drnerctbisa RANN&tAD-g];[ but not adlttn.eas)r NAR spinlcig mzey)e(ns brag RNA and po“ol ;”it na rntion si uct uto nda hte xseon no teihre ised of hte ntoinr rea inoead,dj ilek :hits
eto——onnr2non1xxie t&;=g xe1on2n—xeo
lpyicaylT, shit gnpciils cocrsu at the yvre egdse fo eth rninto w(hat I dedtneo thiw hte ”“— h.a)aetccrr tBu ni our ,seac a tnauotim inwtih eht tnrion si nsciagu ARN cpgilisn ezemyn ot eognecriz a wen t:eis eht psircel stuc inwthi het intnro esdia(tn of ta het yver dgee, sa ti lhodus.) ,oS ew get noihemgst ttah olkso leki :hist
oex1x2n—r—tonine
’sahtT a ttlaloy defenrfit NmAR ocmue,lel and tis' onigg ot amek rou liβb-ogn pietron lkoo a(nd hbeaev) yalwluf ga.sentr
$279$49