Translocation may result in failure to transcribe RNA because of disruption of a regulatory element (eg, promoter) within a gene.
The affected gene will not be expressed or will be expressed in a dysregulated manner compared to the normal phenotype
sThi sha ot do twhi toninr iicsnlg.p mRbreeem AG.TG This tunoitma dcnideu na AG rocsle erhew ti saw usposepd ot be, so meos fo htta ntnori just eecbam an oexn.
I tprtiedrene secqun"ee durnruisgno tisfr wot snoex fo e"gen - to naem ethy muts eb ilgtkna uabto ti.nnors erThe fo het anrswe ocechsi 'otdn ehav umch ot do twih snn.roit
tath aym ton eb ira thi,gt but spelh arnrwo .ndow lsoA ikonnwg smoe aim-htsasaBel si ude to vnisarat ni ronbamla incislgp pl.hse AF( 1029 gp 4)3
laos emmrbree ttha saasalht-eimB is due ot otpni touamtsin ni plcsie tseis and rmeotpro nuceesqse (9FA1 .)p104g fI ouy trecea a ittanmou ni a eplsci seit yuo lwli seulry msse pu eht trcecro NRmA ddneee to amke a tfacnnoiul n-boBlgi tirn.eop hTat is ohw I dwesnrea eth tnu.iqeos
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$279$49As srbddecei in eth qiousnte ,tsme isht oittuamn sccour tnwihi na nointr (a geen gtsemne hiwhc is ieansrbrtdc &NNAD]t-[A;gR but otn atarls)ednt. ANR ciplgsin e(yznm)es rbga RNA nad olop“ ”t;i an intorn is cut uot dan het seonx no hertei seid of eht itonnr aer ,aodienjd eilk ht:is
ox—ti2oxeennrnn—1o ;=&tg no12xone—xe
clyi,pTlya htsi lginpcsi ucorcs ta eht yrve edges fo teh nnroti t(hwa I etdedno hitw eth ”“— trc)c.heara tuB ni oru ae,sc a amutotin hniitw eth nntior is ginaucs ANR silpgicn enzmey to ozineercg a enw es:it eht psrlice ustc tinhwi eht trionn dianes(t of ta the yevr gee,d sa it dsolhu.) So, we teg onehmtigs tath oloks keil shit:
o1xn—n—i2onrexte
sT’aht a ytlaolt ffeitredn mNAR ,elleucom nad t'si ggoin to kaem uor nobgi-lβ eptonri kool dan( av)bhee fllawuy rtnga.es
$279$49