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NBME 27 Answers

respiratory_alkalosis



pharyngeal_arches pierre_robin_sequence
Question#5 (reveal difficulty score)
A 4-day-old male who was born at home is ...
First ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–



tuberculosis
Question#8 (reveal difficulty score)
A 56-year-old man with a history of alcohol ...
Cord factor ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–

Kaposi_sarcoma

survival_curves
Hurler_syndrome
Question#12 (reveal difficulty score)
A 1-year-old girl is brought to the physician ...
alpha-Iduronidase ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–



Question#15 (reveal difficulty score)
A 28-year-old man comes to the physician for ...
Pale, small, normal ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–

Question#16 (reveal difficulty score)
A 60-year-old woman comes to the physician ...
Estrogen therapy ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–



Question#19 (reveal difficulty score)
A 33-year-old African American woman comes to ...
Granuloma formation ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–




Question#23 (reveal difficulty score)
During an experiment, investigators use an in ...
Phagocytosis ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–


Question#25 (reveal difficulty score)
A 7-year-old girl is brought to the physician ...
Septic arthritis ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–


Question#28 (reveal difficulty score)
An investigator is testing the hypothesis ...
Fibronectin ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–

Question#29 (reveal difficulty score)
An autopsy is done on a 50-year-old man who ...
Gait ataxia ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–


Question#31 (reveal difficulty score)
A study is conducted to assess the effects of ...
Self-selection ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–






Yersinia_pestis
Question#37 (reveal difficulty score)
A 19-year-old woman comes to the physician ...
Yersina pestis ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–

rotator_cuff
Question#38 (reveal difficulty score)
A 40-year-old woman who is a construction ...
Infraspinatus ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–



Question#41 (reveal difficulty score)
A 16-year-old girl with cystic fibrosis is ...
Vitamin E ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–



repeat
Question#45 (reveal difficulty score)
An investigator is studying a new hormone, ...
Prolactin ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–


repro
Question#48 (reveal difficulty score)
A 48-year old man with renal artery stenosis ...
Testicular artery ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–



Question#1 (reveal difficulty score)
A 55-year-old woman with a history of alcohol ...
Left gastric ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–


angiogram
imprinting uniparental_disomy


bursitis
Question#7 (reveal difficulty score)
A 60-year-old man comes to the emergency ...
Bursa ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–

homocystinuria


Question#11 (reveal difficulty score)
An 82-year-old woman with type 2 diabetes ...
Substance P ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–


Question#13 (reveal difficulty score)
A 1-year-old girl is admitted to the hospital ...
Enteropeptidase ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–



chronic_myelogenous_leukemia
biostatistics biostats
Question#17 (reveal difficulty score)
A 65-year-old man comes to the physician ...
65% ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–

antibiotics
Question#19 (reveal difficulty score)
A 45-year-old woman is brought to the ...
Struvite ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–





Question#24 (reveal difficulty score)
An investigator creates Drug Z that ...
AUG ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–

scabies


Question#28 (reveal difficulty score)
A 30-year-old woman comes to the physician ...
Kidney ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–


Question#30 (reveal difficulty score)
A 3-year-old boy id brought to the physician ...
Alcohol ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–

Question#31 (reveal difficulty score)
A 48-year-old man comes to the emergency ...
Ciprofloxacin ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–

Question#32 (reveal difficulty score)
A study is conducted to assess body mass ...
Two ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–

personality_disorders
Question#34 (reveal difficulty score)
A female newborn delivered at 26 weeks' ...
Retina ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–





Question#39 (reveal difficulty score)
A 64-year-old homeless man with alcoholism is ...
Folic acid ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–


Question#41 (reveal difficulty score)
A 1-year-old boy is admitted to the hospital ...
รŸ_2 Integrin ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–


shock
neostigmine
Question#44 (reveal difficulty score)
An investigator is studying the effects of ...
Neostigmine ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–



Question#47 (reveal difficulty score)
A 24-year-old woman at 28 weeks' gestation is ...
Tremor ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–

anatomy
Question#48 (reveal difficulty score)
A 7-year-old boy is brought to the physician ...
Atlantoaxial joint ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–


Question#50 (reveal difficulty score)
A 70 year-old-man comes to the office because ...
Cytochrome c ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–




Question#4 (reveal difficulty score)
In some inherited disorders of collagen, ...
Lysine ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–

Question#5 (reveal difficulty score)
An investigator wants to determine if coffee ...
Case-control study ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–

heroin
Question#6 (reveal difficulty score)
A 23-year-old woman is brought to the ...
Heroin ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–


Question#8 (reveal difficulty score)
A 47-year-old woman comes to the emergency ...
Carcinoid tumor ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–

Question#9 (reveal difficulty score)
An investigator is recording the amplitude of ...
Mode < median < mean ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–

diuretics


Question#13 (reveal difficulty score)
A 57-year-old man with a 4-year history of ...
Iron ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–

Question#14 (reveal difficulty score)
An investigator studying the energy ...
One ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–

Question#15 (reveal difficulty score)
The graph shows the plasma concentration of ...
15 ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–

PCOS
Question#16 (reveal difficulty score)
An obese 39-year-old woman with hirsutism and ...
Estrone ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–

Question#17 (reveal difficulty score)
During an experiment, a strain of knockout ...
Cl- ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–


Question#19 (reveal difficulty score)
An 18-year-old woman comes to the physician ...
APOB ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–

Question#20 (reveal difficulty score)
A 16-year-old boy comes to the physician ...
Testosterone ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–

Question#21 (reveal difficulty score)
The graphs depict experiments in which cells ...
Natural killer cell ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–





Question#26 (reveal difficulty score)
A 66-year-old man is brought to the emergency ...
Cigarette smoking ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–


Question#28 (reveal difficulty score)
A 25-year-old woman comes to the physician ...
21-Hydroxylase ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–


Question#30 (reveal difficulty score)
A 45-year-old man receives the diagnosis of ...
Levofloxacin ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–


Question#32 (reveal difficulty score)
In a historical study, 4753 nulliparous women ...
100 ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–

Question#33 (reveal difficulty score)
A 2-month old boy is brought to the physician ...
Peroxisomes ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–



toxoplasmosis toxoplasma_gondii
Question#36 (reveal difficulty score)
A 35-year-old woman with HIV infection has a ...
Ingestion ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–


arrow









Question#48 (reveal difficulty score)
An investigator is studying the selective ...
Astrocytes ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–



Question#1 (reveal difficulty score)
The neoplasm indicated by X in the MRI of the ...
Visual field deficit ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–

Question#2 (reveal difficulty score)
A 70-year-old man has angiodysplasia of the ...
Hemorrhage ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–


Question#49 (reveal difficulty score)
A 71-year-old man comes to the physician ...
Cilostazol ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–



Question#46 (reveal difficulty score)
A 25-year-old woman is brought to the ...
C5-7 ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–

Question#45 (reveal difficulty score)
A 25-year-old man sustains perforation of the ...
Superior mesenteric ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–





ethics communication

Question#38 (reveal difficulty score)
A 2-month old boy is brought to the physician ...
Autosomal recessive ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–






Question#32 (reveal difficulty score)
A 40-year-old woman comes to the physician ...
Heteroplasmy ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–


Question#30 (reveal difficulty score)
A 48-year-old man is brought to the emergency ...
Goodpasture syndrome ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–

NRTIs NNRTIs
Question#28 (reveal difficulty score)
To assess antigen-presenting cell function in ...
B7 ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–

Question#27 (reveal difficulty score)
A 12-year-old boy is brought to the physician ...
Prostaglandin ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–


Question#25 (reveal difficulty score)
A 3-year-old girl is brought to the physician ...
Ferrochelatase ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–

Question#24 (reveal difficulty score)
A 28-year-old nulligravid woman who has been ...
Secretory ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–

Question#23 (reveal difficulty score)
A 55-year-old man comes to the physician ...
Type II ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–


Question#21 (reveal difficulty score)
A 65-year-old man develops his third episode ...
Bronchoscopy ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–


Question#19 (reveal difficulty score)
A previously healthy 54-year-old man comes to ...
Hypovolemia ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–

Question#18 (reveal difficulty score)
A 47-year-old man is admitted to the hospital ...
Increased urine flow ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–



Question#15 (reveal difficulty score)
A 4-year-old boy is brought to the physician ...
Fragile X syndrome ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–

Question#14 (reveal difficulty score)
A 9-year-old girl is brought to the emergency ...
Periosteum ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–

Question#13 (reveal difficulty score)
A screening program is instituted for ...
10% ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–



giardia
gout


Question#6 (reveal difficulty score)
A 27-year-old woman has had severe lower left ...
Uterine tube ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–

hardy_weinberg
Question#5 (reveal difficulty score)
In an isolated population, a single mutation ...
0.2 ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–


Recent comments ...

... โˆ—namesthegame22 made a comment (nbme27)
 +2  submitted by namesthegame22(13)

5a-Reductase catalyzes the metabolism of testosterone to DHT.

Individuals with 5a-reductase deficiency exhibit decreased concentrations of DHT and impaired virilization of the male urogenital tract.

Individuals with 5a-reductase deficiency appear phenotypically female externally or may have ambiguous external genitalia, with normal male internal genitalia.

csalib2  thanks +
... โˆ—shak360 made a comment (nbme27)
 +1  submitted by shak360(19)

(E) alpha-Iduronidase (correct)

The only lysosomal storage disease that presents with corneal clouding (as far as I know) is Hurler's syndrome, which is one of two mucopolysaccharidoses, the other being Hunter syndrome. Hunter syndrome can be distinguished from Hurler syndrome in that Hunter syndrome does not present with corneal clouding (Hunters see clearly [no corneal clouding] and aggressively aim for the X [X-linked recessive]). Hurler's syndrome is due to a deficiency in alpha-L-Iduronidase, and Hunter syndrome is due to a deficiency in Iduronate-2-sulfatase. Both diseases lead to an accumulation of heparan and dermatan sulfate.

... โˆ—shak360 made a comment (nbme27)
 +1  submitted by shak360(19)

(C) Cryptosporidium parvum (correct) vs (E) Giardia lamblia (incorrect)

There are three main protozoa that cause GI infections:

  • Giardia lamblia - which causes fatty, foul-smelling stools, is transmitted via cysts in water (usually unfiltered river or lake water), and on histology, shows a flagellated, pear-shaped trophozoite with two large, central nuclei
  • Entamoeba histolytica - which causes bloody diarrhea or dysentery, liver abscesses, RUQ pain, and presents with flask-shaped ulcers on colon biopsy
  • Cryptosporidium - which causes watery diarrhea in immunocompetent hosts and severe diarrhea in AIDS patients, transmits via oocysts in water, and is an AIDS-defining illness (happens at CD4+ < 100/mm3)
... โˆ—shak360 made a comment (nbme27)
 +1  submitted by shak360(19)

(F) Pleural effusion (correct)

Pleural effusion presents with

  • decreased breath sounds (fluid in the pleural cavity dampens the transmission of sound and mechanical waves)
  • dullness to percussion
  • decreased tactile fremitus

Note that in pleural effusion, these tests are all "dulled" or are all "decreased".

Pneumothorax presents with

  • decreased breath sounds
  • hyperresonance to percussion
  • decreased tactile fremitus

all on the affected side.

Lobar pneumonia (or a consolidated lung) presents with

  • decreased breath sounds
  • dullness to percussion
  • increased tactile fremitus because the consolidated lung is adjacent to the body wall
drdoom  very nice! +1


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