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Retired NBME 27 Answers

nbme27/Block 1/Question#20 (reveal difficulty score)
A 24-year-old man with AIDS comes to the ...
*Cryptosporidium parvum* ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
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submitted by โˆ—shak360(19)
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(C) Cryptosporidium parvum (correct) vs (E) Giardia lamblia (incorrect)

There are three main protozoa that cause GI infections:

  • Giardia lamblia - which causes fatty, foul-smelling stools, is transmitted via cysts in water (usually unfiltered river or lake water), and on histology, shows a flagellated, pear-shaped trophozoite with two large, central nuclei
  • Entamoeba histolytica - which causes bloody diarrhea or dysentery, liver abscesses, RUQ pain, and presents with flask-shaped ulcers on colon biopsy
  • Cryptosporidium - which causes watery diarrhea in immunocompetent hosts and severe diarrhea in AIDS patients, transmits via oocysts in water, and is an AIDS-defining illness (happens at CD4+ < 100/mm3)
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