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Retired NBME 27 Answers

nbme27/Block 1/Question#16 (reveal difficulty score)
A 60-year-old woman comes to the physician ...
Estrogen therapy ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
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submitted by โˆ—shak360(19)
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(C) Early menarche (incorrect)

Early menarche is a risk factor for endometrial carcinoma because it is directly related to the number of ovulatory cycles and endometrial estrogen exposure, but this person has been taking additional estrogen for an additional 10 years after menopause. Estrogen excess without adequate opposition by progestin is a strong risk factor for atypical endometrial hyperplasia and endometrial carcinoma.

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