APO E - mediates remnant uptake (Everything Except LDL) [defective in Familial dyslipidemia type III or dysbetalipoproteinemia - premature atherosclerosis, tuberoeruptive and palmar xanthomas]
APO E2 decreases the risk of the sporadic form of Alzheimer's disease
APO E4 increases the risk of the sporadic form of Alzheimer's disease
APO AI - Found only on Alpha-lipoproteins (HDL), Activates LCAT
APO CII - Lipoprotein lipase Cofactor that Catalyzes Cleavage [defective in Familial dyslipidemia type I or hyperchylomicronemia - increased chylomicrons and increased risk of pancreatitis, hepatosplenomegaly, and eruptive/pruritic xanthomas]
APO B48 - mediates chylomicron secretion into lymphatics and is found only on particles originating from the intestines
APO B100 - Binds LDL receptors and is found only on particles originating from the liver [defective in Familial dyslipidemia type II or familial hypercholesterolemia - tendon (Achilles) xanthomas and corneal arcus]
submitted by โshak360(19)
APO E - mediates remnant uptake (Everything Except LDL) [defective in Familial dyslipidemia type III or dysbetalipoproteinemia - premature atherosclerosis, tuberoeruptive and palmar xanthomas]
APO AI - Found only on Alpha-lipoproteins (HDL), Activates LCAT
APO CII - Lipoprotein lipase Cofactor that Catalyzes Cleavage [defective in Familial dyslipidemia type I or hyperchylomicronemia - increased chylomicrons and increased risk of pancreatitis, hepatosplenomegaly, and eruptive/pruritic xanthomas]
APO B48 - mediates chylomicron secretion into lymphatics and is found only on particles originating from the intestines
APO B100 - Binds LDL receptors and is found only on particles originating from the liver [defective in Familial dyslipidemia type II or familial hypercholesterolemia - tendon (Achilles) xanthomas and corneal arcus]