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NBME 22 Answers

nbme22/Block 4/Question#34 (15.9 difficulty score)
A 17-year-old boy comes to the physician ...
B lymphocyte🔍

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submitted by dr.xx(129),
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ern-BratEips ruivs )BV(E is rraceid by osmt It cna cseau arevles syept fo nracc.e nI atleyhh iefctend ,lpepeo VEB tpiesrss rof flie ni a lt""neta etsta in B lc.les


uw: EBV commonly infects B cells, stimulating them to enter the cell cycle and proliferate continuously ("transformation or "immortalization"). this is accomplished when EBV-encoded activate proliferative and anti-apoptotic signaling pathways w/i the infected B cell. ... the immortalized B cells maintain the ability to secrete Ig and B-cell activation products (eg. CD23), with very few of them releasing virus particles at any one time.