support the site ⋅ become a member ⋅ unscramble the egg
free120  nbme24  nbme23  nbme22  nbme21  nbme20  nbme19  nbme18  nbme17  nbme16  nbme15  nbme13 

NBME 22 Answers

nbme22/Block 4/Question#25 (22.5 difficulty score)
A healthy 25-year-old man eats a meal ...
Fusion of an intracellular vesicle with the plasma membrane🔍

Login to comment/vote.

In a pancreatic B cell glucose enters via GLUT 2 and enters glycolysis. This causes the increased concentration of ATP in the cell causes the closure of ATP sensitive K+ channels. When this happens the cells becomes depolarized allowing Voltage gated Ca2+ channels to be open. The Ca2+ allows for exocytosis of insulin into the blood vessel.

Hence the answer here... Fusion of an intracellular vesicle with the plasma membrane.

pg 324 FA 2019 has the image

brotherimodu  Woah. Who knew the body was so complicated? +  

unscramble the site ⋅ become a member ($36/month)

clylasaib gouslec tueasimtls atBe clesl to sctxyeooe .isunlin Any rsposec lnnvgvoii soctsoxeiy isevonvl sofuin of na nurlactelirla evlcise ihtw the lasapm ran.mmbee

unscramble the site ⋅ become a member ($36/month)

aailsylbc clseguo tlamsueits tBea elslc to otoycxse An sceorps vvlniniog oetiosycxs lneiosvv niusof do an culltialnerar seilecv tihw eth lapsma n.ermebam

 -11  upvote downvote
submitted by dr.xx(125),
unscramble the site ⋅ become a member ($36/month)

ehT l-csleβ ahve velvoed a asemicnhm ot ttdcee eht naomut of iiunsnl odtser adn ertecsde and tjudas iuinsnl iyhesnsts drcal.cnygio A naugerl resmabarentnm inpteor ladlce ilets ellc etaintgauon 125 5)C,12AI( is a acrilcu tapr of tsih bafecekd lorn.oct Ilsiunn auneslgr rveatl a nolg iedstcna on iubutln skract oberfe irngvira at teh rpaelehpri ciant nrekwot [1.]52 Breeof enmocigb ekidnl to hte c,tyltoneeoks unilsin eusnrlga era adrnohce ot icnat oetrcx iva 152ACI adn h-pyio2hnrtsnβ. Uopn tanacvtoii, eth urlaeng neabmmre fessu litannytres ot eth lcel reemabmn ot alerees nsl.iiun aEtleevd C+a2 elvsle in het aiemenmt ctatevai hte tseorpae laa-inpμc ot elveac awya a cclyisoto rmegtfna rmfo .51AIC2 eTh efre A1I5C2 oisylocct rtfnaegm neth omvse to eht ucuelns nda nsdib ot het i-ostetpaprloydroehsnyh nnptastiirlaorc ofacrt STAT5 to nerevtp TTSA 5 ormf lhaodisootp,hepnry ihhwc in untr leteagupsru ulinins ncatptsioirnr 12]7.[ Nrueacl refe IC5A21 lyccotios gnaermsft olsa idnb to snoiyugaltm eznyme AγPSI. The soyiaonultm fo 1C2A5I by IAPS γ rsvsreee het idnngbi fo A1IC52 to SAT5T [.12]7 n,eHce hte arleees of insinlu rmof crtoyseer luaregns si emdtimcnuoca to hte cu,lensu whhic serves sa a ovseiipt cedekfab michsamne ot eiintati lnuinsi lrtistannao orf gmnnaitniia na euqatade moantu of trosde slnu.nii


anjum  Bro wat r u doin with this explanation +1