how to remember its lamber eaton and not MG: it doesn't matter how much you move your muscle the ach receptor is blocked the same amount and ach release will by repetitive movement is not gonna change the number of available receptors in Lambert the more you move the muscle the more calcium is released to fuse the vesicle with the plasma membrane and if finally you get enough concentration of calcium in the cell, you will merge the vesicle with the plasma membrane and enough a normal amount of ach is in the synapse.
antibodies form against the presynaptive Ca2+ channels at the NMJ-most commonly seen in patients with small cell lung cancer
antibodies form against the presynaptive Ca2+ channels at the NMJ-most commonly seen in patients with small cell lung cancer
This question is pretty bad because down regulation of calcium channels in PREsynaptic neurons would result in LESS ACh release onto the motor-end plate, which would cause down signaling and impaired excitation-extraction coupling of muscle. This is because that mechanism needs depolarization and release of calcium to work.
I guess you just can't overthink it lol.
submitted by โwelpdedelp(270)
This is Lambert-Eaton, which improves with movement as compared to Myesthenia gracias whichh worsens with movement