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NBME 22 Answers

nbme22/Block 4/Question#3 (27.8 difficulty score)
A 60-year-old man comes to the physician ...
Alveolar macrophageπŸ”
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 +11 
submitted by welpdedelp(225),
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tI wsa a negisruurFo -d;&bteoi-sg ets.oissbsa urFironuesg bdesio are deeeibvl ot eb eomrfd yb sapgrheomca htat haev coopdaetsghy dan pteatdetm to gidtes het .fesrbi

almondbreeze  info about ferruginous bodies being mf can't be found on FA/UW :'( they just say it's 'material' +  
taediggity  FA 2020 677, FA 2019 659... mf?? mofos?? +3  
69_nbme_420  Just to add: The question asks what cell type initiated the Fibrosis β†’ Alveolar macrophages engulf the particles and induce fibrosis (same pathophys for all Pneumoconiosis). Pathoma 2019 Pg 92 +7  



 +0 
submitted by syoung07(27),

Pneumoconioses get allllll the way down to our alveoli to cause fibrosis and thus restrictive lung dz. Alveoli dont have the mucociliary elevator to clear shit so they depend on macrophages to get rid of substances.