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NBME 22 Answers

nbme22/Block 2/Question#44 (19.1 difficulty score)
A 3-day-old full-term male newborn is brought ...
Hepatic UDP-glucuronosyltransferase activity🔍,📺
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 +4 
submitted by ilikecheese(47),
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eehrT si a gihh eincdrit iilirnubb otrinaocectnn 8( mdlg/ out fo eth lotta 01 ld/)mg os trhee sutm eb a emboplr ithw tgnjinucoa.o hte eemnyz denede ofr iocajuotngn si reeln-sfuoP.tDgsUlnoarryas

In itsh e,asc hsit is poscaiyilholg naolneat aucdneji. eud to iemtrmau enymez that ssleoerv iwhtuot atemttren ni -21 spek. egw 738 AF 9102




 +2 
submitted by waterloo(89),

I was between hepatic excretion of bilirubin and Hepatic UDP-gluco.... (Rotor syndrome and gilbert/physiologic neonatal jaundice respectively).

FA 387 (2019) helps where they say

  • high UCB (indirect) --> Crigler Najjar or Gilbert syndrome, or physiologic neonatal jaundice.
  • high CB (direct): think excretion defect for this type of vignette (Rotor Syndrome). Had the question said "with a direct component of 8" I think I would have chosen Hepatic Excretion of bilirubin.



 +1 
submitted by dantescuttlefish(5),
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Bbeias tnod' heva armtue attviyci of tish nmeeyz nhwe ftisr b..r.oxnT ithw otp.ttoohhe.rnay.p asme ammiencsh sa eemzny tub aeskm bnbilriui eomr leusobl