NBME 22 O, Rh-negative (NBME Answers)

Retired NBME 22 Answers

nbme22/Block 1/Question#16 (reveal difficulty score)
An Rh-negative woman, gravida 3, para 2, has ...
O, Rh-negative 🔍 / 📺 / 🌳 / 📖
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+11 upvote downvote
submitted by ∗usmleuser007(464)

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Mother is Rh-neg --> she will generate RH-antibodies 1) fetus affected by Anti-Rh if it is Rh-positive 2) even if O-Rh-Positive is given, then still mother's Rh-antibodies will attack transfused blood due to its cells containing Rh+ 3) therefore, O-Rh-negative is best

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makinallkindzofgainz you're not wrong, but I think it's better to have put O-negative because that's the preferred type of RBC for transfusion unless you've type and crossed your patient +2

mtkilimanjaro I think fetus is O+ but if you give them that the RBCs will still be destroyed. You want to give O- as it wont get destroyed and wont affect the fetus in any way. Similar mechanism to giving platelets to someone with TTP, HUS, etc. they just get destroyed so its useless +1

tylerwill33 In utero, should give O- to avoid mom attacking again. After birth, O+ probably better. +1

+5 upvote downvote
submitted by ∗keycompany(351)

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O, Rh-negative blood is the universal donor for blood plasma.

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keycompany Edit:: Blood RBCs*** +5

peteralamir I thought the O, Rh-negative blood was universal for Blood Cell transfuion, while AB, Rh-Positive was the universal for blood plasma (Since it lacks Ab to A,B, and Rh+ cells) +

-1 upvote downvote
submitted by ∗humble_station(85)

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The mother is Rh - & fetus is Rh +

pg 397 FA 2019 Administration of anti-D IgG to Rh - pregnant mother during 3rd trimester & early postpartum period (if fetus Rh+)

Prevents maternal anti-D IgG production

anti-D IgG = O, Rh -

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snripper Not sure why you're getting downvoted, but this makes sense to me. Maybe because you're claiming that the fetus is Rh+ when it's not clearly stated? But take that away and your explanation still makes sense. +2

j000 the question is not asking what to give to the mother. it's asking what to give to the fetus. +3

kani is the baby not having hemolytic reaction. thats what i thought was happining. and you give a blood type the same as the baby. +

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