This patient presents with a mitochondrial myopathy since the disorder is inherited from the mother. Mitochondrial myopathies show “ragged red fibers” on muscle biopsy due to the accumulation of diseased mitochondria in the subsarcolemma of the muscle fiber.
katsuMitochondrial myopathies—rare disorders; often present with myopathy, lactic acidosis, and CNS disease, eg, MELAS syndrome (mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes). 2° to failure in oxidative phosphorylation. Muscle biopsy often shows “ragged red fibers” (due to accumulation of diseased mitochondria).+2019-07-14T01:23:22Z
does anyone know what the structure E is pointing to?
thomasburtonNot sure looks like it might be free ribosomes or other such small cytosolic structure (I picked E too, thought B looked way too big!)+2019-08-15T19:03:47Z
targetusmlesame here!! marked e thinking of it as a mitochondria+12019-08-18T05:57:30Z
msyrettGlycogen Granules! They are not membrane bound and float freely in the cytoplasm.+2019-11-09T19:28:37Z
to snoo-finity ... and beyond!
submitted by lianallado(2), 2019-06-16T19:21:38Z
This patient presents with a mitochondrial myopathy since the disorder is inherited from the mother. Mitochondrial myopathies show “ragged red fibers” on muscle biopsy due to the accumulation of diseased mitochondria in the subsarcolemma of the muscle fiber.