Why no sweating? I mean I get Ecstasy is probably the drug of choice before an all night dance party (lol) but don't understand why there would be cold extremities and no sweating when is FA it says hyperthermia and rhabdo????
sympathetikeyFA says, "euphoria, disinhibition, hyperactivity, distorted sensory and time perception, bruxism.
Lifethreatening effects include hypertension, tachycardia, hyperthermia, hyponatremia, serotonin syndrome."
So I think they wanted you to see Sinus Tachy and jump for MDMA. Idk why Ketamine couldn't also potentially be correct though.+22019-06-04T22:59:47Z
amorahI picked ketamine because it said no diaphoresis. But if you need to find a reason, I guess the half life of ketamine might rule it out. Remember from sketchy, ketamine is used for anaesthesia induction, so probably won't keep the HR and BP high for 8 hrs. In fact, its action is ~10-15 mins-ish iv. +52019-06-07T23:20:51Z
yotsubatoBecause the NBME is full of fuckers. The guy is probably dehydrated so he cant sweat anymore? +92019-06-16T12:30:36Z
fulminant_lifeyou wouldnt see tachycardia with ketamine. It causes cardiovascular depression but honestly i saw " all-night dance party" picked the mdma answer and moved on lol+62019-06-16T22:41:01Z
monkdKetamine acts as a sympathomimetic but oh well. NBME hasn't caught on to ketamine as a drug of recreation :)+2019-06-23T21:03:22Z
dashou19Take a look at why the patient has pale and cold extremities.
"Mechanistic clinical studies indicate that the MDMA-induced elevations in body temperature in humans partially depend on the MDMA-induced release of norepinephrine and involve enhanced metabolic heat generation and cutaneous vasoconstriction, resulting in impaired heat dissipation."
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008716/+22019-09-23T03:17:45Z
drzed@sbryant6 you're both saying the same thing. Ketamine has a direct negative inotropic effect on the heart, but it is also a sympathomimetic. You are both correct. +2020-02-06T17:59:40Z
paperbackwriter@drzed Can you please site that? As far as I understand ketamine has a sympathomimetic effect on the CV system --> increased chronotropy and BP. I also don't see how they're saying the same thing. One person said "stimulation" and the other said "depression"+2020-02-17T03:42:53Z
to snoo-finity ... and beyond!
submitted by mousie(127), 2019-06-04T17:27:01Z
Why no sweating? I mean I get Ecstasy is probably the drug of choice before an all night dance party (lol) but don't understand why there would be cold extremities and no sweating when is FA it says hyperthermia and rhabdo????