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NBME 22 Answers

nbme22/Block 4/Question#17 (17.4 difficulty score)
A 62-year-old man with dyslipidemia is ...
Gemfibrozil🔍,📺
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 +2 
submitted by castlblack(59),

Highest yield drug combo to avoid on NBME, Kaplan, and UWorld.

skonys  I see it so much I dont even know why it's a thing. I just choose it everytime. +  



 +0 
submitted by luckeroo(10),
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yhw aws itsh gbzlefriiom nda tno i?nncia I aws uckyl nad eegdu,ss btu I gthohut caiinn obmencid dluoc saol ergrigt hympao?ty

.ooo.   Gemfibrozil is a CYP450 inhibitor causing an increase drug concentration of statin which would lead to the adverse side effect of myopathy. Not sure about niacin in combination with statin but believe this would be more likely to occur. Hope this helps! +1  
yb_26  yes, it can be seen with niacin and esetemibe as well, according to UWorld. But first choice in such questions is always fibrates. +  
nor16  number one no-go combi is statin+fibrate here +3