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NBME 22 Answers

nbme22/Block 3/Question#32

A 25-year-old woman comes to the physician because ...

Fasting insulin: increased;
Testosterone: increased;
Luteinizing hormone: increased

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submitted by mcl(378),

Patient likely has PCOS. PCOS is associated with elevated levels of LH from the pituitary, which stimulates ovaries to produce increased amounts of sex steroids (including androgens --> hirsutisim). Androstenedione is converted to estrone in adipocytes, which results in still further increased release of LH. Obesity and insulin resistance is associated with PCOS.