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NBME 22 Answers

nbme22/Block 3/Question#17

A 50-year-old man with chronic gastritis is ...

Helicobacter pylori

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1) EBV = Burkitt lymphoma, Hodgkin lymphoma, nasopharyngeal carcinoma, 1° CNS lymphoma (in immunocompromised patients)

2) HBV & HCV = Hepatocellular carcinoma

3)HHV-8 = Kaposi sarcoma

4) HPV= Cervical and penile/anal carcinoma (types 16, 18), head and neck cancer

5) H. pylori = Gastric adenocarcinoma and MALT lymphoma

6) HTLV-1 = Adult T-cell leukemia/lymphoma

7) Liver fluke (Clonorchis sinensis) = Cholangiocarcinoma

8) Schistosoma haematobium = Bladder cancer (squamous cell)

some0217710  Aren’t both H.pylori and EBV associated with gastric lymphoma? +1  

FA 2017: H pylori is associated with gastric adenocarcinoma and MALT lymphoma

seagull  I might be mistaken but I also thought Epstein Bar Virus was also implicated in gastric lymphomas? +  

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submitted by link981(35),

Marginal zone lymphoma is caused by CHRONIC INFLAMMATION. H-Pylori can cause chronic inflammation in the stomach.

Epstein barr virus is associated with BURKITT lymphoma, the JAW lesion in Africa.

Got it wrong because I thought H-Pylori only caused gastric cancer.