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NBME 22 Answers

nbme22/Block 2/Question#25

A 37-year-old woman undergoes excision of a 1-cm, ...


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 +4  upvote downvote
submitted by armymed88(29),

Wound healing inflammatory for up til 3 days (clots, PMNs, macros) Proliferative 3days til weeks- granulation tissue, new vessels, new epithelium, contraction (repair and regeneration) Remodel 1wk til 6m- replace collagen III with I, increase strength (up to 60-70% original strength possible)

john055  it looks like the patient has new onset erythema which points to infection and I think neutrophils make sense. I myself have marked angiogenesis but I did it offline. Is angiogenesis the right answer ? +  
almondbreeze  yup +  
almondbreeze  according to FA 2019 pg217, neutrophil is present during inflammatory phase- i.e. only up to 3d after the wound. After that we have the proliferative phase with granulation tiss. and angiogenesis, epithelial cell proliferation, dissolution of clot, and wound contraction (involved cells: fibroblasts, myofibroblasts, endothelial cells, keratinocytes, mf) +  
mitchell_to_lakers  why not fibrosis? +  

 +1  upvote downvote
submitted by btl_nyc(24),

Proliferative phase of wound healing. FA 2019 pg 217

 +0  upvote downvote
submitted by asharm10(0),

It,s not an infection, it's basically a healing process, angiogenesis leads to warmth and erythema,