It appears that although NRTIs are phosphorylated by thymidine kinase, resistance is actually due to mutations in the actual reverse transcriptase rather than thymidine kinase itself.
foreroforemutations in thymine kinase are more frequent in herpes drugs+2019-07-20T17:50:43Z
mtfpNRTI need to be phosphorylated by HOST CELL thymidine kinase, mutation in viral kinase has no role in NRTI resistance+2019-11-14T13:26:36Z
to snoo-finity ... and beyond!
submitted by lamhtu(31), 2019-06-09T23:46:03Z
It appears that although NRTIs are phosphorylated by thymidine kinase, resistance is actually due to mutations in the actual reverse transcriptase rather than thymidine kinase itself.