Kim! Hi! It’s your dad!👋 ▪ Khalilah, I’m proud of you for taking a risk for your dream.Everyone’s explanations tend to be so on-point, and the commiseration makes me feel better, too—thanks for the support & good luck studying!                       want to add a message here? just email us!
share email twitter ⋅ join discord whatsapp(2ck)
Free 120  NBME 24  NBME 23  NBME 22  NBME 21  NBME 20  NBME 19  NBME 18  NBME 17  NBME 16  NBME 15  NBME 13 
search for anything NEW!
NBME 21 Answers

nbme21/Block 1/Question#48 (36.5 difficulty score)
A 44-year-old man is admitted to the hospital ...
Increasing cGMP🔍,📺

Login to comment/vote.

Tutor box

Members from the Leaderboard offering 1-on-1 help: Want to be listed here? Email us!

submitted by divya(63),
unscramble the site ⋅ remove ads ⋅ become a member ($39/month)

ineearsc ni MPcA ()sG - bat2e - dnlovaiiosta

csadeere in cAPM Gi() - 2lahap - otsavtrocincnios

creaenis in 3PI GAD )Gq( - hlpa1a - itrvoioncncsasot

sniraeec in GcMP - 3M - NO ceniddu inoalsdtvioa

cytotoxict  Alpha 2 agonists do not cause vasoconstriction b/c they lead to negative feedback of norepi and thus decrease sympathetic response +  
payingforthisisdumb  FA20 p317 α2-agonists increase NO/cGMP and vasodilate +  
sarahs  why is decreasing cAMP wrong? +  
hiroshimi  @sarahs: you want to increase cAMP because it would lead to vasodilation and help to decrease his blood pressure. Decreasing cAMP would make his BP worse. +  

submitted by vi_capsule(14),
unscramble the site ⋅ remove ads ⋅ become a member ($39/month)

HTN ,eegnmycer mSoudi u.Nitoedprsris Uilken zyerlaiadnh a alebndac odasairolvt ine(v = at)ierlro

sympathetikey  Well then, I guess we should just forget about our old pals the Alpha-2 agonists. Good call. I didn't even see that this was hypertensive emergency. Dumb on my part. +  
zup  so yea clonidine would be used for hypertensive urgency, but this guy is over 180 (210) so they have to use something like hydralazine or nitroprusside both will increase cGMP +  
whoissaad  Drugs used to treat HTN emergency: Nitroprusside Labetolol Nicardipine Clevidpine Fenoldapam Clonidine +16  
lola915  Hydralazine actually vasodilates arteries>veins and Nitroprusside vasodilates arteries = veins. Both increase cGMP. +10