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NBME 20 Answers

nbme20/Block 3/Question#15 (37.3 difficulty score)
A 23-year-old woman, who was diagnosed with ...
Substance P🔍,📺

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submitted by poisonivy(33),
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Pre Wro;Uld iaascinpc uondf ni ichil pprpsee sacues vxsseceei aiavictont of P1VRT esmrnmnbreat(a n)nacl,eh hcwih esaienscr rruealliatncl mluccai htta seurstl in natlgl-ginos ndfyouintsc fo ticiepnecov nerev irbsfe .idonaucnzf(te)iitnaol It olsa aescsu aelsree adn oleentipd of Sueascntb ,P scuagin at rftis gribunn dna hetmyear ubt veor tmie eucssa esceaeddr inpa .tnasoenis

submitted by hayayah(1101),
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cbusStean P P()S is an pieecuaptnedd sepnter in the SCN and het ppileaherr rveunso esy.stm A conpumdo ttghhou ot eb dvlivnoe in teh npisctya sasnnormtiis fo pnai dan rhoet renev e.iulssmp

mambaforstep  also, apparently enkephalins attenuate substance p... so it would be dec her pain. +1  

submitted by ssc30(4),

Per FA2020 pg 551.

Substance P release is inhibited with opioid analgesics. Therefor connecting the relationship between Substance P and pain. Enkephalin is a type of opioid receptor which is involved in this pathway but is not a neurotransmitter as the question asked for.

submitted by poisonivy(33),
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Pre ;WrdUol acinapcis donuf in lihic ppespre suesac escevxsie aaconttivi fo PR1TV eanertrmsmn(ab cn,hn)lae whihc scenraies lraeacrnutlli icamucl hatt stselur in i-ltgnalosgn innsyufdoct fo ccviietpnoe veern bersfi n) tI salo usaces eelraes nad eliedntop of Sbsenuact P, nasgicu at sfrit binungr nad hrmeyate tub ovre imet casuse sdecdaere apni si.etsnano

chandlerbas  also topical Rx for post herpetic neuralgia +  

submitted by step1soon(46),
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inscCpiaa nisdcue teh eeeslar fo asnuetbcs P, one fo eht iprclpani drmceosoi-etmha of pnia ieslumps rfmo the eyrrhipep ot hte tnralce srnuveo tymses NS(.)C erftA peeadret oianitp,alpc acspacini dpseetle the nnruoe fo uesctanbs P dna reepvnst tsi cncr.almuuatieo